Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Benjamin J. Hindson"'
Autor:
Grace X. Y. Zheng, Jessica M. Terry, Phillip Belgrader, Paul Ryvkin, Zachary W. Bent, Ryan Wilson, Solongo B. Ziraldo, Tobias D. Wheeler, Geoff P. McDermott, Junjie Zhu, Mark T. Gregory, Joe Shuga, Luz Montesclaros, Jason G. Underwood, Donald A. Masquelier, Stefanie Y. Nishimura, Michael Schnall-Levin, Paul W. Wyatt, Christopher M. Hindson, Rajiv Bharadwaj, Alexander Wong, Kevin D. Ness, Lan W. Beppu, H. Joachim Deeg, Christopher McFarland, Keith R. Loeb, William J. Valente, Nolan G. Ericson, Emily A. Stevens, Jerald P. Radich, Tarjei S. Mikkelsen, Benjamin J. Hindson, Jason H. Bielas
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Single-cell gene expression analysis is challenging. This work describes a new droplet-based single cell RNA-seq platform capable of processing tens of thousands of cells across 8 independent samples in minutes, and demonstrates cellular subtypes and
Externí odkaz:
https://doaj.org/article/9c33171e807745c7908a1e1e9a3712e3
Autor:
Rajiv Bharadwaj, Paul Wyatt, Joe Shuga, Donald A. Masquelier, Tarjei S. Mikkelsen, Mark T. Gregory, Junjie Zhu, Jerald P. Radich, Emily A. Stevens, Solongo B. Ziraldo, Christopher McFarland, Luz Montesclaros, Nolan G. Ericson, Alexander Wong, William J. Valente, Benjamin J. Hindson, Tobias Daniel Wheeler, Jason G. Underwood, H. Joachim Deeg, Jessica M. Terry, Kevin D. Ness, Phillip Belgrader, Stefanie Y. Nishimura, Geoffrey P. McDermott, Michael Schnall-Levin, Jason H. Bielas, Zachary Bent, Lan Beppu, Paul Ryvkin, Christopher Hindson, Grace X.Y. Zheng, Keith R. Loeb, Ryan Wilson
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Nature Communications
Nature Communications
Characterizing the transcriptome of individual cells is fundamental to understanding complex biological systems. We describe a droplet-based system that enables 3′ mRNA counting of tens of thousands of single cells per sample. Cell encapsulation, o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c253cde04091540cdaa92d1bfadff133
https://doi.org/10.1038/ncomms14049
https://doi.org/10.1038/ncomms14049
Autor:
Claudia Litterst, Adam Lowe, Geoffrey P. McDermott, Yann Jouvenot, Pramod Walse, Pallavi Shah, Leanne Javier, Benjamin J. Hindson, Shenglong Wang, Thomas H. Cauly, Eli Hefner, John F. Regan, Svilen Tzonev, Luc J. Bousse, David P. Stumbo, Keith Hamby, Paul Wyatt, Timothy P. Brackbill, Tina C. Legler, Jennifer R. Berman, Yunfeng Ling, Amy L. Hiddessen, Chunxiao Han, Josephine Wong, Niels Klitgord, Samuel H. Marrs, Adam Bemis, George Karlin-Neumann, Viresh P. Patel, Ryan T. Koehler, Erin R. Steenblock, Dianna Maar, David Sally, Duc Do, Theresa Dinio, Christopher Hindson, Shawn Hodges, George Carman
Publikováno v:
Analytical Chemistry. 85:11619-11627
Two years ago, we described the first droplet digital PCR (ddPCR) system aimed at empowering all researchers with a tool that removes the substantial uncertainties associated with using the analogue standard, quantitative real-time PCR (qPCR). This s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::029e8a582b6689d56d0e6e1c46964120
https://doi.org/10.1021/ac403061n
https://doi.org/10.1021/ac403061n
Autor:
Benjamin J. Hindson, Ryan T. Koehler, John F. Regan, Alexandra Brown, Stephanie C. Tanner, Phillip Belgrader
Publikováno v:
Clinical Chemistry. 59:991-994
BACKGROUND Human epidermal growth factor receptor 2 (HER2) testing is routinely performed by immunohistochemistry (IHC) and/or fluorescence in situ hybridization (FISH) analyses for all new cases of invasive breast carcinoma. IHC is easier to perform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0500c86dc32374fb18740cda61ccc46b
https://doi.org/10.1373/clinchem.2012.197855
https://doi.org/10.1373/clinchem.2012.197855
Autor:
Nolan G. Ericson, Alexander Wong, Keith R. Loeb, Ryan Wilson, Zachary Bent, Emily A. Stevens, Tobias Daniel Wheeler, Rajiv Bharadwaj, H. Joachim Deeg, Jessica M. Terry, William J. Valente, Jason H. Bielas, Kevin D. Ness, Phillip Belgrader, Lan Beppu, Paul Ryvkin, Tarjei S. Mikkelsen, Geoffrey P. McDermott, Jerald P. Radich, Donald A. Masquelier, Solongo B. Ziraldo, Mark T. Gregory, Luz Montesclaros, Grace X.Y. Zheng, Christopher McFarland, Paul Wyatt, Christopher Hindson, Joe Shuga, Stefanie Y. Nishimura, Benjamin J. Hindson, Michael Schnall-Levin, Junjie Zhu
Characterizing the transcriptome of individual cells is fundamental to understanding complex biological systems. We describe a droplet-based system that enables 3′ mRNA counting of up to tens of thousands of single cells per sample. Cell encapsulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7bb5ac0446559ec783467c8c0c59dd7
https://doi.org/10.1101/065912
https://doi.org/10.1101/065912
Autor:
Rajiv Bharadwaj, Hanlee P. Ji, Serge Saxonov, Alex Kindwall, Melissa Luo, Patrick Marks, Clara Bermejo, Landon Merrill, Francesca Meschi, Jessica M. Terry, Adrian Fehr, John Bell, Gerard M Vurens, Kristina Giorda, Adam Lowe, Heather Ordonez, Michael Schnall-Levin, Jorge Bernate, Josephine Y Lee, Phillip Belgrader, Glenn K. Lockwood, Steven W Short, Sukhvinder Kaur, Shawn Gauby, Lawrence Greenfield, Geoffrey P. McDermott, Stephanie Greer, Pranav Patel, Andrew D. Price, Benjamin J. Hindson, Nikola O Kondov, Grace X.Y. Zheng, Sofia Kyriazopoulou-Panagiotopoulou, David E Birch, Luz Montesclaros, Alexander Wong, Kamila Belhocine, Susan M. Grimes, Ryan Wilson, Donald A. Masquelier, Patrice A Mudivarti, Kevin D. Ness, Mirna Jarosz, Adrian Chan, Indira Wu, Erik S. Hopmans, Paul Wyatt, David Stafford, Paul Hardenbol, Anthony J. Makarewicz, Joshua Delaney, Yuan Li, Zachary Bent, Christopher Hindson, Christina Wood, Keith Bjornson, Billy T. Lau, William Haynes Heaton
Publikováno v:
Nature biotechnology, vol 34, iss 3
Haplotyping of human chromosomes is a prerequisite for cataloguing the full repertoire of genetic variation. We present a microfluidics-based, linked-read sequencing technology that can phase and haplotype germline and cancer genomes using nanograms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61cceca38f7f8889494f6c31fa5fc631
https://escholarship.org/uc/item/0z84g4gh
https://escholarship.org/uc/item/0z84g4gh
Autor:
Leonardo B. Pinheiro, Christopher Hindson, Benjamin J. Hindson, Kerry R. Emslie, Victoria A. Coleman, Somanath Bhat, Jan Herrmann
Publikováno v:
Analytical Chemistry
Droplet digital polymerase chain reaction (ddPCR) is a new technology that was recently commercialized to enable the precise quantification of target nucleic acids in a sample. ddPCR measures absolute quantities by counting nucleic acid molecules enc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98c6f59d3230a6e182a1813b0aadeb90
http://europepmc.org/articles/PMC3260738
http://europepmc.org/articles/PMC3260738
Autor:
Nicholas G. Erndt, Christopher Hindson, Shenglong Wang, Isaac J. Bright, Dean K. Wittmann, Pallavi Shah, Tyler K. Kitano, Serge Saxonov, Jonathan Petersen, Fred P. Milanovich, Steven Romine, Luz Montesclaros, Phillip Belgrader, Paul Wyatt, John F. Regan, Thomas H. Cauley, Kevin D. Ness, Michael R. Hodel, Luc J. Bousse, Tina C. Legler, Donald A. Masquelier, George Karlin-Neumann, Ryan T. Koehler, Benjamin J. Hindson, Amy L. Hiddessen, Helen E. White, David P. Stumbo, Camille B. Troup, Simant Dube, Michael Y. Lucero, Shawn Hodges, Austin P. So, Erin R. Steenblock, Nicholas J. Heredia, Anthony J. Makarewicz, Bill W. Colston, Jeffrey Clark Mellen, Klint Rose
Publikováno v:
Analytical Chemistry
Digital PCR enables the absolute quantitation of nucleic acids in a sample. The lack of scalable and practical technologies for digital PCR implementation has hampered the widespread adoption of this inherently powerful technique. Here we describe a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c756d564e2be69fb020e17310af955a8
http://europepmc.org/articles/PMC3216358
http://europepmc.org/articles/PMC3216358
Autor:
Paul S. Francis, Thomas R. Metz, William B. Benett, Ujwal S. Setlur, John M. Dzenitis, J.M. Loge, Neil W. Barnett, Anthony J. Makarewicz, Dora M. Gutierrez, Kevin D. Ness, Bill W. Colston, Benjamin J. Hindson
Publikováno v:
The Analyst. 133:248-255
We present a fully automated DNA purification module comprised of a micro-fabricated chip and sequential injection analysis system that is designed for use within autonomous instruments that continuously monitor the environment for the presence of bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c19a5bcd20e50bf9b38a1d6a08ba4c43
https://doi.org/10.1039/b713332d
https://doi.org/10.1039/b713332d
Autor:
Josue I. Ortiz, Hilary Holland, Benjamin J. Hindson, Mary T. McBride, Timothy J. Salo, Julie Perkins, Alfonso Clavijo
Publikováno v:
Journal of Veterinary Diagnostic Investigation. 19:180-184
Initial results demonstrating the feasibility of a multiplexed liquid array immunoassay for foot-and-mouth disease viral antigen detection and simultaneous serotype differentiation are presented. Serotype-specific antibodies from rabbit and guinea pi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7ef1a19bff80c18493989ccd1718575
https://doi.org/10.1177/104063870701900207
https://doi.org/10.1177/104063870701900207