Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Benjamin J. Frisch"'
Autor:
Azmeer Sharipol, Benjamin J. Frisch
Publikováno v:
Frontiers in Hematology, Vol 3 (2024)
Acute myeloid leukemia (AML) is the most aggressive adult leukemia and results in a dismal 5-year survival rate of less than 30%. While research has primarily focused on identifying intrinsic mutations driving leukemogenesis, the role of the bone mar
Externí odkaz:
https://doaj.org/article/050739882ff24b749f1271580b49731d
Publikováno v:
Journal of Bone Oncology, Vol 45, Iss , Pp 100575- (2024)
Externí odkaz:
https://doaj.org/article/6e7e7c9e513e4ba8bea6c54c1d675c92
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Hematopoiesis takes place in the bone marrow and is supported by a complex cellular and molecular network in the bone marrow microenvironment. Commonly used models of the human bone marrow microenvironment include murine models and two-dimensional an
Externí odkaz:
https://doaj.org/article/3fd0f8822d7c4deb8f1832dd678e652f
Publikováno v:
JBMR Plus, Vol 5, Iss 10, Pp n/a-n/a (2021)
Abstract The bone marrow microenvironment (BMME) regulates hematopoiesis through a complex network of cellular and molecular components. Hematologic malignancies reside within, and extensively interact with, the same BMME. These interactions conseque
Externí odkaz:
https://doaj.org/article/2987e1e0c2ff4eb2b3ae6c26cf05eb69
Autor:
Edward Ayoub, Michael P. Wilson, Kathleen E. McGrath, Allison J. Li, Benjamin J. Frisch, James Palis, Laura M. Calvi, Yi Zhang, Archibald S. Perkins
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-12 (2018)
Chr3q26 rearrangements cause overexpression of EVI1 and associate with myeloid neoplasms, but the mechanism behind this association is unclear. Here, using a novel mouse model they show that EVI1 causes premalignant myeloid expansion with suppression
Externí odkaz:
https://doaj.org/article/7ab778ef571e43deb286e077ef67c640
Autor:
Jozal W. Moore, Jason H. Mendler, Kah Poh (melissa) Loh, Mitra Azadniv, Kristen M. O'Dwyer, Eric J. Huselton, Frank Akwaa, Benjamin J. Frisch, Myla Strawderman, Mark W. LaMere, Daniel K. Byun, Alyssa C. Jasper, Michael W. Becker, Jane L. Liesveld, Laura M. Calvi
Publikováno v:
Blood. 140:4050-4052
Autor:
Yuko Kawano, Hiroki Kawano, Dalia Ghoneim, Thomas J. Fountaine, Daniel K Byun, Mark W. LaMere, Jason H. Mendler, Tzu-Chieh Ho, Noah A. Salama, Benjamin J. Frisch, Jason R. Myers, Siba El Hussein, John M. Ashton, Mitra Azadniv, Jane L. Liesveld, Youmna Kfoury, David T. Scadden, Michael W. Becker, Laura M. Calvi
SUMMARYMesenchymal stem/stromal cells (MSCs) within the bone marrow microenvironment (BMME) support normal hematopoietic stem and progenitor cells (HSPCs). However, the heterogeneity of human MSCs has limited the understanding of their contribution t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1620cde45bc77078164157cecacc53e6
https://doi.org/10.1101/2023.04.09.536176
https://doi.org/10.1101/2023.04.09.536176
Publikováno v:
Blood. 140:8620-8621
Autor:
Benjamin J. Frisch, Laura M. Calvi, James Palis, Tanzy Love, Paul D. Kingsley, Anne D. Koniski, Jacqueline P. Williams
Publikováno v:
International Journal of Radiation Biology. 95:1447-1461
Purpose: Incidents, such as nuclear facility accidents and the release of a ‘dirty bomb’, might result in not only external irradiation of personnel, but additional internal exposures through conco...