Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Benjamin J. Deadman"'
Autor:
Olga C. Dennehy, Valérie M. Y. Cacheux, Benjamin J. Deadman, Denis Lynch, Stuart G. Collins, Humphrey A. Moynihan, Anita R. Maguire
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 2511-2522 (2016)
A continuous process strategy has been developed for the preparation of α-thio-β-chloroacrylamides, a class of highly versatile synthetic intermediates. Flow platforms to generate the α-chloroamide and α-thioamide precursors were successfully ado
Externí odkaz:
https://doaj.org/article/bfd668290bbe4f4d845686eaa020ed8e
Autor:
Benjamin J. Deadman, Sarah Gian, Violet Eng Yee Lee, Luis A. Adrio, Klaus Hellgardt, King Kuok (Mimi) Hii
Publikováno v:
Green Chemistry. 24:5570-5578
Using the dihydroxylation of alkenes as a benchmark, the reactivities of fresh and aged solutions of (NH4)2S2O8 (electrochemically generated) were compared to commercially-procured peroxydisulfate and Oxone®. The study revealed that peroxymonosulfat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5c2ba8234c80906d1eb263bce46e938
https://doi.org/10.1039/d2gc00671e
https://doi.org/10.1039/d2gc00671e
Autor:
Roderick T. Stark, Dominic R. Pye, Wenyi Chen, Oliver J. Newton, Benjamin J. Deadman, Philip W. Miller, Jenny-Lee Panayides, Darren L. Riley, Klaus Hellgardt, King Kuok (Mimi) Hii
A synthetic route to an anti-cancer drug, lapatinib, was devised to support the development of a sustainable manufacturing process in South Africa. Quantitative metrics were employed to evaluate the sustainability of the key steps of the reaction.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf9f055551c476d4e44a59076bcd63bd
http://hdl.handle.net/10044/1/99067
http://hdl.handle.net/10044/1/99067
Publikováno v:
Reaction Chemistry & Engineering. 2:462-466
Redox colorimetric tests have been devised for the rapid analysis of the individual components of aqueous mixtures of peroxodisulfate, peroxomonosulfate and hydrogen peroxide; providing a convenient and selective method for the determination of these
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2fe52f909eec4f25282d528896a3b86
https://doi.org/10.1039/c7re00050b
https://doi.org/10.1039/c7re00050b
Autor:
Florence O. McCarthy, Nicholas D. Mullins, Jonathan Thompson, Benjamin J. Deadman, Simon E. Lawrence, Anita R. Maguire, Humphrey A. Moynihan
Publikováno v:
Journal of Pharmaceutical Analysis
A systematic approach was developed to investigate the stability of gentamicin sulfate (GS) and GS/poly (lactic-co-glycolic acid) (PLGA) coatings on hydroxyapatite surfaces. The influence of environmental factors (light, humidity, oxidation and heat)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90d6e6d22a76dba973681736d2b78ddd
https://doi.org/10.1016/j.jpha.2016.05.002
https://doi.org/10.1016/j.jpha.2016.05.002
Autor:
Benjamin J. Deadman, Rosella M. O'Mahony, Stuart G. Collins, Daniel C. Crowley, Denis Lynch, Anita R. Maguire
Publikováno v:
Organic & Biomolecular Chemistry. 14:3423-3431
Heat and shock sensitive tosyl azide was generated and used on demand in a telescoped diazo transfer process. Small quantities of tosyl azide were accessed in a 'one pot' batch procedure using shelf stable, readily available reagents. For large scale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369e7848f1eec40357e7dfc7ec0fd522
https://doi.org/10.1039/c6ob00246c
https://doi.org/10.1039/c6ob00246c
Autor:
Claudio Battilocchio, Benjamin N. Bhawal, Steven V. Ley, Joel M. Hawkins, Rajeev Chorghade, Benjamin J. Deadman
Publikováno v:
Israel Journal of Chemistry. 54:371-380
A flow chemistry procedure for Sonogashira and Heck cross-coupling reactions using a low-level palladium perovskite catalyst (LaFe0.95Pd0.05O3) deposited on cerium oxide is reported. The catalyst was generated in situ at high temperature using a flow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ff524c6823a146271c3899112c0e3476
https://doi.org/10.1002/ijch.201300049
https://doi.org/10.1002/ijch.201300049
Autor:
Valérie M Y Cacheux, Denis Lynch, Anita R. Maguire, Olga C. Dennehy, Benjamin J. Deadman, Stuart G. Collins, Humphrey A. Moynihan
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 12, Iss 1, Pp 2511-2522 (2016)
Beilstein Journal of Organic Chemistry
Beilstein Journal of Organic Chemistry
A continuous process strategy has been developed for the preparation of α-thio-β-chloroacrylamides, a class of highly versatile synthetic intermediates. Flow platforms to generate the α-chloroamide and α-thioamide precursors were successfully ado
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6d3243dc8182443d6d8d2aaafaa65d8
http://hdl.handle.net/10044/1/42730
http://hdl.handle.net/10044/1/42730
Continuous-flow generation of α-diazosulfoxides results in a two- to three-fold increase in yields and decreased reaction times compared to standard batch synthesis methods. These high yielding reactions are enabled by flowing through a bed of polys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::325852f785d392790d8466086d7864c3
http://hdl.handle.net/10044/1/37069
http://hdl.handle.net/10044/1/37069
Autor:
Benjamin J. Deadman, Ian R. Baxendale, Duncan L. Browne, Steven V. Ley, Samantha Dunnage, Steven Wright, Richard M. Turner
Publikováno v:
Rapid Communications in Mass Spectrometry. 26:1999-2010
RATIONALE A recently developed miniature electrospray ionisation mass spectrometer has been coupled to a preparative flow chemistry system in order to monitor reactive intermediates and competing reaction paths, screen starting materials, and optimis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0b6209d5447a1279f6c1ff54daed3ab1
https://doi.org/10.1002/rcm.6312
https://doi.org/10.1002/rcm.6312