Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Benjamin J McLean"'
Autor:
Phoebe A. Phillips, Yordanos F. Setargew, Benjamin J. McLean, Jorjina Kasparian, Koroush S. Haghighi, Jennifer P. Morton, Thomas P. Davis, Minoti V. Apte, Nigel Turner, Marina Pajic, Yi Fang Guan, Val Gebski, Estrella Gonzales-Aloy, Anthony J. Gill, Amber Johns, Angela Chou, Julia Lee, Nelson Russia, Jie Liu, Stephanie Naim, Rosa Mistica C. Ignacio, Owen J. Sansom, Andrew D. Campbell, Arafath K. Najumudeen, Sigrid K. Fey, Jessica L. Chitty, Brooke A. Pereira, Thomas R. Cox, Paul Timpson, David Goldstein, Mert Erkan, Cyrille Boyer, Jeff Holst, John Kokkinos, Janet Youkhana, Chantal Kopecky, Anouschka Akerman, Joshua A. McCarroll, George Sharbeen
Cancer-associated fibroblasts (CAF) are major contributors to pancreatic ductal adenocarcinoma (PDAC) progression through protumor signaling and the generation of fibrosis, the latter of which creates a physical barrier to drugs. CAF inhibition is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::86d65521fa58365f055bbf9ff1e8f1ff
https://doi.org/10.1158/0008-5472.c.6512931.v1
https://doi.org/10.1158/0008-5472.c.6512931.v1
Autor:
Phoebe A. Phillips, Yordanos F. Setargew, Benjamin J. McLean, Jorjina Kasparian, Koroush S. Haghighi, Jennifer P. Morton, Thomas P. Davis, Minoti V. Apte, Nigel Turner, Marina Pajic, Yi Fang Guan, Val Gebski, Estrella Gonzales-Aloy, Anthony J. Gill, Amber Johns, Angela Chou, Julia Lee, Nelson Russia, Jie Liu, Stephanie Naim, Rosa Mistica C. Ignacio, Owen J. Sansom, Andrew D. Campbell, Arafath K. Najumudeen, Sigrid K. Fey, Jessica L. Chitty, Brooke A. Pereira, Thomas R. Cox, Paul Timpson, David Goldstein, Mert Erkan, Cyrille Boyer, Jeff Holst, John Kokkinos, Janet Youkhana, Chantal Kopecky, Anouschka Akerman, Joshua A. McCarroll, George Sharbeen
SLC7A11 knockdown in PDAC CAFs does not affect glutamate secretion and is maintained in the presence of oxidative stress.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6392a8bb5adc4a0965731494b29c63cd
https://doi.org/10.1158/0008-5472.22428168
https://doi.org/10.1158/0008-5472.22428168
Autor:
Phoebe A. Phillips, Yordanos F. Setargew, Benjamin J. McLean, Jorjina Kasparian, Koroush S. Haghighi, Jennifer P. Morton, Thomas P. Davis, Minoti V. Apte, Nigel Turner, Marina Pajic, Yi Fang Guan, Val Gebski, Estrella Gonzales-Aloy, Anthony J. Gill, Amber Johns, Angela Chou, Julia Lee, Nelson Russia, Jie Liu, Stephanie Naim, Rosa Mistica C. Ignacio, Owen J. Sansom, Andrew D. Campbell, Arafath K. Najumudeen, Sigrid K. Fey, Jessica L. Chitty, Brooke A. Pereira, Thomas R. Cox, Paul Timpson, David Goldstein, Mert Erkan, Cyrille Boyer, Jeff Holst, John Kokkinos, Janet Youkhana, Chantal Kopecky, Anouschka Akerman, Joshua A. McCarroll, George Sharbeen
Australian Pancreatic Cancer Genome Initiative International Cancer Genome Cohort patient cohort characteristics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::07924398ea68cfd9441878bf940f9c25
https://doi.org/10.1158/0008-5472.22428159.v1
https://doi.org/10.1158/0008-5472.22428159.v1
Autor:
Phoebe A. Phillips, Yordanos F. Setargew, Benjamin J. McLean, Jorjina Kasparian, Koroush S. Haghighi, Jennifer P. Morton, Thomas P. Davis, Minoti V. Apte, Nigel Turner, Marina Pajic, Yi Fang Guan, Val Gebski, Estrella Gonzales-Aloy, Anthony J. Gill, Amber Johns, Angela Chou, Julia Lee, Nelson Russia, Jie Liu, Stephanie Naim, Rosa Mistica C. Ignacio, Owen J. Sansom, Andrew D. Campbell, Arafath K. Najumudeen, Sigrid K. Fey, Jessica L. Chitty, Brooke A. Pereira, Thomas R. Cox, Paul Timpson, David Goldstein, Mert Erkan, Cyrille Boyer, Jeff Holst, John Kokkinos, Janet Youkhana, Chantal Kopecky, Anouschka Akerman, Joshua A. McCarroll, George Sharbeen
Validation of SLC7A11 antibodies and SLC7A11 knockdown in CAFs and PDAC cells in vitro.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72013e9e007e3b98eaf2dff92c16d58a
https://doi.org/10.1158/0008-5472.22428180.v1
https://doi.org/10.1158/0008-5472.22428180.v1
Autor:
Phoebe A. Phillips, Yordanos F. Setargew, Benjamin J. McLean, Jorjina Kasparian, Koroush S. Haghighi, Jennifer P. Morton, Thomas P. Davis, Minoti V. Apte, Nigel Turner, Marina Pajic, Yi Fang Guan, Val Gebski, Estrella Gonzales-Aloy, Anthony J. Gill, Amber Johns, Angela Chou, Julia Lee, Nelson Russia, Jie Liu, Stephanie Naim, Rosa Mistica C. Ignacio, Owen J. Sansom, Andrew D. Campbell, Arafath K. Najumudeen, Sigrid K. Fey, Jessica L. Chitty, Brooke A. Pereira, Thomas R. Cox, Paul Timpson, David Goldstein, Mert Erkan, Cyrille Boyer, Jeff Holst, John Kokkinos, Janet Youkhana, Chantal Kopecky, Anouschka Akerman, Joshua A. McCarroll, George Sharbeen
Confirmation of SLC7A11 knockdown in KPC tumour cells and CAFs and collagen fibril analysis in tumour sections at therapeutic model endpoint.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::847a842fa9498592d91de7ad3a77d89a
https://doi.org/10.1158/0008-5472.22428165
https://doi.org/10.1158/0008-5472.22428165
Autor:
Phoebe A. Phillips, Yordanos F. Setargew, Benjamin J. McLean, Jorjina Kasparian, Koroush S. Haghighi, Jennifer P. Morton, Thomas P. Davis, Minoti V. Apte, Nigel Turner, Marina Pajic, Yi Fang Guan, Val Gebski, Estrella Gonzales-Aloy, Anthony J. Gill, Amber Johns, Angela Chou, Julia Lee, Nelson Russia, Jie Liu, Stephanie Naim, Rosa Mistica C. Ignacio, Owen J. Sansom, Andrew D. Campbell, Arafath K. Najumudeen, Sigrid K. Fey, Jessica L. Chitty, Brooke A. Pereira, Thomas R. Cox, Paul Timpson, David Goldstein, Mert Erkan, Cyrille Boyer, Jeff Holst, John Kokkinos, Janet Youkhana, Chantal Kopecky, Anouschka Akerman, Joshua A. McCarroll, George Sharbeen
Anti-proliferative effect of SLC7A11 knockdown in CAFs and the effect of SLC7A11 inhibition in MiaPaCa-2 PDAC cells and normal human pancreatic ductal epithelial (HPDE) cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34674c8b07429434bb3f0b74d2121e97
https://doi.org/10.1158/0008-5472.22428177.v1
https://doi.org/10.1158/0008-5472.22428177.v1
Autor:
Phoebe A. Phillips, Yordanos F. Setargew, Benjamin J. McLean, Jorjina Kasparian, Koroush S. Haghighi, Jennifer P. Morton, Thomas P. Davis, Minoti V. Apte, Nigel Turner, Marina Pajic, Yi Fang Guan, Val Gebski, Estrella Gonzales-Aloy, Anthony J. Gill, Amber Johns, Angela Chou, Julia Lee, Nelson Russia, Jie Liu, Stephanie Naim, Rosa Mistica C. Ignacio, Owen J. Sansom, Andrew D. Campbell, Arafath K. Najumudeen, Sigrid K. Fey, Jessica L. Chitty, Brooke A. Pereira, Thomas R. Cox, Paul Timpson, David Goldstein, Mert Erkan, Cyrille Boyer, Jeff Holst, John Kokkinos, Janet Youkhana, Chantal Kopecky, Anouschka Akerman, Joshua A. McCarroll, George Sharbeen
SLC7A11 multivariate survival analysis parameters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::904ffe21be5abe42d7185d5ba7397801
https://doi.org/10.1158/0008-5472.22428153
https://doi.org/10.1158/0008-5472.22428153
Autor:
Phoebe A. Phillips, Yordanos F. Setargew, Benjamin J. McLean, Jorjina Kasparian, Koroush S. Haghighi, Jennifer P. Morton, Thomas P. Davis, Minoti V. Apte, Nigel Turner, Marina Pajic, Yi Fang Guan, Val Gebski, Estrella Gonzales-Aloy, Anthony J. Gill, Amber Johns, Angela Chou, Julia Lee, Nelson Russia, Jie Liu, Stephanie Naim, Rosa Mistica C. Ignacio, Owen J. Sansom, Andrew D. Campbell, Arafath K. Najumudeen, Sigrid K. Fey, Jessica L. Chitty, Brooke A. Pereira, Thomas R. Cox, Paul Timpson, David Goldstein, Mert Erkan, Cyrille Boyer, Jeff Holst, John Kokkinos, Janet Youkhana, Chantal Kopecky, Anouschka Akerman, Joshua A. McCarroll, George Sharbeen
SLC7A11 expression in iCAFs, myCAFs and quiescent PSCs.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::808ef4660452ab93221aac03e1411470
https://doi.org/10.1158/0008-5472.22428156.v1
https://doi.org/10.1158/0008-5472.22428156.v1
Autor:
Phoebe A. Phillips, Yordanos F. Setargew, Benjamin J. McLean, Jorjina Kasparian, Koroush S. Haghighi, Jennifer P. Morton, Thomas P. Davis, Minoti V. Apte, Nigel Turner, Marina Pajic, Yi Fang Guan, Val Gebski, Estrella Gonzales-Aloy, Anthony J. Gill, Amber Johns, Angela Chou, Julia Lee, Nelson Russia, Jie Liu, Stephanie Naim, Rosa Mistica C. Ignacio, Owen J. Sansom, Andrew D. Campbell, Arafath K. Najumudeen, Sigrid K. Fey, Jessica L. Chitty, Brooke A. Pereira, Thomas R. Cox, Paul Timpson, David Goldstein, Mert Erkan, Cyrille Boyer, Jeff Holst, John Kokkinos, Janet Youkhana, Chantal Kopecky, Anouschka Akerman, Joshua A. McCarroll, George Sharbeen
List of antibodies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79790572ce906bedc370e2151b3fa4b4
https://doi.org/10.1158/0008-5472.22428162
https://doi.org/10.1158/0008-5472.22428162
Autor:
Mert Erkan, Julia Lee, Marina Pajic, Janet Youkhana, Anouschka Akerman, Nelson Russia, Amber L. Johns, Thomas P. Davis, Thomas R. Cox, Jie Liu, Jessica L. Chitty, Rosa Mistica C. Ignacio, Angela Chou, George Sharbeen, Yordanos F I Setargew, Yi Fang Guan, Andrew D. Campbell, Joshua A. McCarroll, Jeff Holst, Jennifer P. Morton, Nigel Turner, Arafath Kaja Najumudeen, Koroush S. Haghighi, Estrella Gonzales-Aloy, Phoebe A. Phillips, Owen J. Sansom, Paul Timpson, Val Gebski, Chantal Kopecky, Sigrid K. Fey, Minoti V. Apte, Cyrille Boyer, Brooke A. Pereira, David Goldstein, Stephanie Naim, John Kokkinos, Anthony J. Gill, Jorjina Kasparian, Benjamin J McLean
Publikováno v:
Cancer Research
Cancer-associated fibroblasts (CAF) are major contributors to pancreatic ductal adenocarcinoma (PDAC) progression through protumor signaling and the generation of fibrosis, the latter of which creates a physical barrier to drugs. CAF inhibition is th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ef2f04e3bd86332b0646ae479e3af1f
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/10025
http://cdm21054.contentdm.oclc.org/cdm/ref/collection/IR/id/10025