Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Benjamin J, Yungher"'
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/3332515a4d1b4249bc3fba882965296d
Autor:
Xueting Luo, Marcio Ribeiro, Eric R. Bray, Do-Hun Lee, Benjamin J. Yungher, Saloni T. Mehta, Kinjal A. Thakor, Francisca Diaz, Jae K. Lee, Carlos T. Moraes, John L. Bixby, Vance P. Lemmon, Kevin K. Park
Publikováno v:
Cell Reports, Vol 15, Iss 2, Pp 398-410 (2016)
Signal transducer and activator of transcription 3 (STAT3) is a transcription factor central to axon regrowth with an enigmatic ability to act in different subcellular regions independently of its transcriptional roles. However, its roles in mature C
Externí odkaz:
https://doaj.org/article/b2e6c11a964241089ed85d9b5858d3c9
Autor:
Márcio Ribeiro, Samer Hattar, Gennady Dvoryanchikov, Konstantin Levay, Eric R. Bray, Kevin K. Park, Matt C. Danzi, Nirupa Chaudhari, Victoria S. Marks, Michael Randolph, Vance Lemmon, Ana C. Ayupe, Benjamin J. Yungher, Kinjal Thakor, Tiffany M. Schmidt
Publikováno v:
Neuron
Neuronal subtypes show diverse injury responses, but the molecular underpinnings remain elusive. Using transgenic mice that allow reliable visualization of axonal fate, we demonstrate that intrinsically photosensitive retinal ganglion cells (ipRGCs)
Publikováno v:
Gene therapy
Lack of axon growth ability in the central nervous system poses a major barrier to achieving functional connectivity after injury. Thus, a non-transgenic regenerative approach to reinnervating targets has important implications in clinical and resear
Publikováno v:
Investigative Ophthalmology & Visual Science
Purpose Enhanced regeneration of retinal ganglion cell (RGC) axons can be achieved by modification of numerous neuronal-intrinsic factors. However, axon growth initiation and the pathfinding behavior of these axons after traumatic injury remain poorl
Autor:
Kevin K, Park, Xueting, Luo, Skyler J, Mooney, Benjamin J, Yungher, Stephane, Belin, Chen, Wang, Melissa M, Holmes, Zhigang, He
Publikováno v:
The Journal of comparative neurology. 525(2)
In the adult mammalian central nervous system (CNS), axonal damage often triggers neuronal cell death and glial activation, with very limited spontaneous axon regeneration. In this study, we performed optic nerve injury in adult naked mole-rats, the
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 34(46)
Mammalian target of rapamycin (mTOR) functions as a master sensor of nutrients and energy, and controls protein translation and cell growth. Deletion of phosphatase and tensin homolog (PTEN) in adult CNS neurons promotes regeneration of injured axons