Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Benjamin J, Metcalf"'
Autor:
Cebile Lekhuleni, Kedibone Ndlangisa, Rebecca A. Gladstone, Sopio Chochua, Benjamin J. Metcalf, Yuan Li, Jackie Kleynhans, Linda de Gouveia, Scott Hazelhurst, Ana D. S. Ferreira, Happy Skosana, Sibongile Walaza, Vanessa Quan, Susan Meiring, Paulina A. Hawkins, Lesley McGee, Stephen D. Bentley, Cheryl Cohen, Stephanie W. Lo, Anne von Gottberg, Mignon du Plessis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Invasive pneumococcal disease (IPD) due to non-vaccine serotypes after the introduction of pneumococcal conjugate vaccines (PCV) remains a global concern. This study used pathogen genomics to evaluate changes in invasive pneumococcal lineage
Externí odkaz:
https://doaj.org/article/428323113fd04185bfd8dcf4843186a7
Autor:
Yvette Unoarumhi, Morgan L. Davis, Lori A. Rowe, Saundra Mathis, Zhongya Li, Sopio Chochua, Yuan Li, Lesley McGee, Benjamin J. Metcalf, Justin S. Lee, Bernard Beall
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Group A streptococcal strains potentially acquire new M protein gene types through genetic recombination (emm switching). To detect such variants, we screened 12,596 invasive GAS genomes for strains of differing emm types that shared the sam
Externí odkaz:
https://doaj.org/article/7970d727ab21431580305f89bac2fe3e
Autor:
Yuan Li, Joy Rivers, Saundra Mathis, Zhongya Li, Sopio Chochua, Benjamin J. Metcalf, Bernard Beall, Jennifer Onukwube, Christopher J. Gregory, Lesley McGee
Publikováno v:
Emerging Infectious Diseases, Vol 29, Iss 10, Pp 2116-2120 (2023)
From 2015–2018 to 2019‒2021, hypertoxigenic M1UK lineage among invasive group A Streptococcus increased in the United States (1.7%, 21/1,230 to 11%, 65/603; p
Externí odkaz:
https://doaj.org/article/13098321002042c1aa98d5325af4de76
Publikováno v:
Epidemics, Vol 45, Iss , Pp 100731- (2023)
Streptococcus pneumoniae is an opportunistic pathogen that, while usually carried asymptomatically, can cause severe invasive diseases like meningitis and bacteremic pneumonia. A central goal in S. pneumoniae public health management is to identify w
Externí odkaz:
https://doaj.org/article/dacb1dd08b9742848b9b50adb8d89104
Autor:
Lingzi Xiaoli, Jill V. Hagey, Daniel J. Park, Christopher A. Gulvik, Erin L. Young, Nabil-Fareed Alikhan, Adrian Lawsin, Norman Hassell, Kristen Knipe, Kelly F. Oakeson, Adam C. Retchless, Migun Shakya, Chien-Chi Lo, Patrick Chain, Andrew J. Page, Benjamin J. Metcalf, Michelle Su, Jessica Rowell, Eshaw Vidyaprakash, Clinton R. Paden, Andrew D. Huang, Dawn Roellig, Ketan Patel, Kathryn Winglee, Michael R. Weigand, Lee S. Katz
Publikováno v:
PeerJ, Vol 10, p e13821 (2022)
Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of coronavirus disease 2019 (COVID-19), has spread globally and is being surveilled with an international genome sequencing effort. Surveillance consists of sample acq
Externí odkaz:
https://doaj.org/article/033c7731831d472d8e1b1f2ae506a9c5
Autor:
Sopio Chochua, Joy Rivers, Saundra Mathis, Zhongya Li, Srinivasan Velusamy, Lesley McGee, Chris Van Beneden, Yuan Li, Benjamin J. Metcalf, Bernard Beall
Publikováno v:
Emerging Infectious Diseases, Vol 25, Iss 8, Pp 1543-1547 (2019)
The term group A Streptococcus is considered synonymous for the species Streptococcus pyogenes. We describe an emergent invasive S. dysgalactiae subspecies equisimilis lineage that obtained the group A antigen through a single ancestral recombination
Externí odkaz:
https://doaj.org/article/75eba97c08344d50b46bd566ef422bcc
Autor:
Yuan Li, Benjamin J. Metcalf, Sopio Chochua, Zhongya Li, Hollis Walker, Theresa Tran, Paulina A. Hawkins, Ryan Gierke, Tamara Pilishvili, Lesley McGee, Bernard W. Beall
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Meningitis is a severe form of invasive pneumococcal disease (IPD). To study the contribution of bacterial genomic variation, here Li et al. perform whole genome sequencing of pneumococcal isolates from IPD patients and identify an association for hi
Externí odkaz:
https://doaj.org/article/3981a36b97a44b1f8420f9609ccbf4bd
Autor:
Yuan Li, Joy Rivers, Saundra Mathis, Zhongya Li, Srinivasan Velusamy, Srinivas A. Nanduri, Chris A. Van Beneden, Paula Snippes-Vagnone, Ruth Lynfield, Lesley McGee, Sopio Chochua, Benjamin J. Metcalf, Bernard Beall
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
BackgroundStreptococcus pyogenes is a major cause of severe, invasive infections in humans. The bacterial pathogen harbors a wide array of virulence factors and exhibits high genomic diversity. Rapid changes of circulating strains in a community are
Externí odkaz:
https://doaj.org/article/d56fa7885eea4217a293e541a7c775ee
Autor:
Yuan Li, Benjamin J. Metcalf, Sopio Chochua, Zhongya Li, Robert E. Gertz, Hollis Walker, Paulina A. Hawkins, Theresa Tran, Lesley McGee, Bernard W. Beall, on behalf of the Active Bacterial Core surveillance team
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-10 (2017)
Abstract Background Genomic sequence-based deduction of antibiotic minimum inhibitory concentration (MIC) has great potential to enhance the speed and sensitivity of antimicrobial susceptibility testing. We previously developed a penicillin-binding p
Externí odkaz:
https://doaj.org/article/9bcdc519306643b7b010d7a0e734e2e3
Autor:
Sopio Chochua, Benjamin J. Metcalf, Zhongya Li, Hollis Walker, Theresa Tran, Lesley McGee, Bernard Beall
Publikováno v:
Emerging Infectious Diseases, Vol 23, Iss 6, Pp 922-930 (2017)
We used whole-genome sequencing to characterize 199 nonvaccine serotype 35B pneumococcal strains that caused invasive pneumococcal disease (IPD) in the United States during 2015–2016 and related these findings to previous serotype 35B IPD data obta
Externí odkaz:
https://doaj.org/article/dbb9eed66fcf4b5f90098c40debeeb30