Zobrazeno 1 - 10
of 1 737
pro vyhledávání: '"Benjamin J, Cowling"'
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Forecasting influenza activity in tropical and subtropical regions, such as Hong Kong, is challenging due to irregular seasonality and high variability. We develop a diverse set of statistical, machine learning, and deep learning approaches
Externí odkaz:
https://doaj.org/article/7941c47197a14ecfaf61d53c72fc6518
Autor:
Tim K. Tsang, Sheena G. Sullivan, Yu Meng, Francisco Tsz Tsun Lai, Min Fan, Xiaotong Huang, Yun Lin, Liping Peng, Chengyao Zhang, Bingyi Yang, Kylie E. C. Ainslie, Benjamin J. Cowling
Publikováno v:
BMC Medicine, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Extending the dosing interval of a primary series of mRNA COVID-19 vaccination has been employed to reduce myocarditis risk in adolescents, but previous evaluation of impact on vaccine effectiveness (VE) is limited to risk after s
Externí odkaz:
https://doaj.org/article/a05b63bd76964e7bab4b1c7702bde9bf
Autor:
Carolyn A. Cohen, Nancy H. L. Leung, Prathanporn Kaewpreedee, Kelly W. K. Lee, Janice Zhirong Jia, Alan W. L. Cheung, Samuel M. S. Cheng, Masashi Mori, Dennis K. M. Ip, Leo L. M. Poon, J. S. Malik Peiris, Benjamin J. Cowling, Sophie A. Valkenburg
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Whole virion inactivated vaccine CoronaVac (C) and Spike (S) mRNA BNT162b2 (B) vaccines differ greatly in their ability to elicit neutralizing antibodies but have somewhat comparable effectiveness in protecting from severe COVID-19. We condu
Externí odkaz:
https://doaj.org/article/43c352f9d77447a8b416c96995ea3831
Autor:
Zaolan Liang, Xia Lin, Lihong Sun, Kimberly M. Edwards, Wenjun Song, Hailiang Sun, Yanmin Xie, Fangmei Lin, Shiman Ling, Tingting Liang, Biying Xiao, Jiaqi Wang, Min Li, Chin-Yu Leung, Huachen Zhu, Nisha Bhandari, Raghavan Varadarajan, Min Z. Levine, Malik Peiris, Robert Webster, Vijaykrishna Dhanasekaran, Nancy H. L. Leung, Benjamin J. Cowling, Richard J. Webby, Mariette Ducatez, Mark Zanin, Sook-San Wong
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Human cases of avian influenza virus (AIV) infections are associated with an age-specific disease burden. As the influenza virus N2 neuraminidase (NA) gene was introduced from avian sources during the 1957 pandemic, we investigate the reacti
Externí odkaz:
https://doaj.org/article/222177c2a96944b098415e28af694ad7
Autor:
Carlos K. H. Wong, Kristy T. K. Lau, Ivan C. H. Au, Sophelia H. S. Chan, Eric H. Y. Lau, Benjamin J. Cowling, Gabriel M. Leung
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-7 (2024)
Abstract Currently there is a lack of randomized trial data examining the use of the antiviral nirmatrelvir/ritonavir in paediatric patients with SARS-CoV-2 infection. This target trial emulation study aims to address this gap by evaluating the use o
Externí odkaz:
https://doaj.org/article/231ad1a19f524d35b5f0b8d19196631d
Publikováno v:
Journal of Infection and Public Health, Vol 17, Iss 9, Pp 102515- (2024)
Background: Guided by the data from the surveillance system, public health efforts have contributed to reducing the burden of influenza in many countries. During the COVID-19 pandemic, many surveillance resources were directed at tracking the severe
Externí odkaz:
https://doaj.org/article/221799eebcef4dc089241c045b47e9cb
Autor:
Janice Z. Jia, Carolyn A. Cohen, Haogao Gu, Milla R. McLean, Raghavan Varadarajan, Nisha Bhandari, Malik Peiris, Gabriel M. Leung, Leo L. M. Poon, Tim Tsang, Amy W. Chung, Benjamin J. Cowling, Nancy H. L. Leung, Sophie A. Valkenburg
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Cross-reactive antibodies with Fc receptor (FcR) effector functions may mitigate pandemic virus impact in the absence of neutralizing antibodies. In this exploratory study, we use serum from a randomized placebo-controlled trial of seasonal
Externí odkaz:
https://doaj.org/article/c15b260c86f84dffa03009a6bb0b59de
Autor:
Samuel M.S. Cheng, Chris K.P. Mok, John K.C. Li, Ken K.P. Chan, Kristine S. Luk, Ben H.W. Lee, Haogao Gu, Karl C.K. Chan, Leo C.H. Tsang, Karen Y.S. Yiu, Ken K.C. Ling, Yun Sang Tang, Leo L.H. Luk, Jennifer K.M. Yu, Andrew Pekosz, Richard J. Webby, Benjamin J. Cowling, David S.C. Hui, Malik Peiris
Publikováno v:
Virology Journal, Vol 21, Iss 1, Pp 1-7 (2024)
Abstract Since the emergence of SARS-CoV-2, different variants and subvariants successively emerged to dominate global virus circulation as a result of immune evasion, replication fitness or both. COVID-19 vaccines continue to be updated in response
Externí odkaz:
https://doaj.org/article/cae027fed4c2433e84e3eea247f4eedb
Autor:
Oliver Eales, Michael J. Plank, Benjamin J. Cowling, Benjamin P. Howden, Adam J. Kucharski, Sheena G. Sullivan, Katelijn Vandemaele, Cecile Viboud, Steven Riley, James M. McCaw, Freya M. Shearer
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 2, Pp 1-9 (2024)
To support the ongoing management of viral respiratory diseases while transitioning out of the acute phase of the COVID-19 pandemic, many countries are moving toward an integrated model of surveillance for SARS-CoV-2, influenza virus, and other respi
Externí odkaz:
https://doaj.org/article/319a30ee0b1248fd8ac88bcf0d7a88ba
Autor:
Yuan Bai, Zhanwei Du, Lin Wang, Eric H.Y. Lau, Isaac Chun-Hai Fung, Petter Holme, Benjamin J. Cowling, Alison P. Galvani, Robert M. Krug, Lauren Ancel Meyers
Publikováno v:
Emerging Infectious Diseases, Vol 30, Iss 2, Pp 262-269 (2024)
We evaluated the population-level benefits of expanding treatment with the antiviral drug Paxlovid (nirmatrelvir/ritonavir) in the United States for SARS-CoV-2 Omicron variant infections. Using a multiscale mathematical model, we found that treating
Externí odkaz:
https://doaj.org/article/4653e5e2b94b43c391f1da180f05c86f