Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Benjamin J, Blyth"'
Autor:
Takafumi Nakayama, Masaaki Sunaoshi, Yi Shang, Mizuki Takahashi, Takato Saito, Benjamin J Blyth, Yoshiko Amasaki, Kazuhiro Daino, Yoshiya Shimada, Akira Tachibana, Shizuko Kakinuma
Publikováno v:
PLoS ONE, Vol 18, Iss 1, p e0280560 (2023)
Calorie restriction (CR) suppresses not only spontaneous but also chemical- and radiation-induced carcinogenesis. Our previous study revealed that the cancer-preventive effect of CR is tissue dependent and that CR does not effectively prevent the dev
Externí odkaz:
https://doaj.org/article/d593dc7b262f475e8791f1b1924e1242
Autor:
Kaushalya C. Amarasinghe, Jamie Lopes, Julian Beraldo, Nicole Kiss, Nicholas Bucknell, Sarah Everitt, Price Jackson, Cassandra Litchfield, Linda Denehy, Benjamin J. Blyth, Shankar Siva, Michael MacManus, David Ball, Jason Li, Nicholas Hardcastle
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundMuscle wasting (Sarcopenia) is associated with poor outcomes in cancer patients. Early identification of sarcopenia can facilitate nutritional and exercise intervention. Cross-sectional skeletal muscle (SM) area at the third lumbar vertebra
Externí odkaz:
https://doaj.org/article/ad2705d0aea644a8a844c6fa9ec72609
Autor:
Truc T. Huynh, Ellen M. van Dam, Sreeja Sreekumar, Cedric Mpoy, Benjamin J. Blyth, Fenella Muntz, Matthew J. Harris, Buck E. Rogers
Publikováno v:
Pharmaceuticals, Vol 15, Iss 6, p 728 (2022)
The gastrin-releasing peptide receptor (GRPR) is a promising molecular target for imaging and therapy of prostate cancer using bombesin peptides that bind to the receptor with high affinity. Targeted copper theranostics (TCTs) using copper radionucli
Externí odkaz:
https://doaj.org/article/6b47add857c6406db5f89e77d7494c0d
Autor:
Masaaki Sunaoshi, Benjamin J. Blyth, Yi Shang, Chizuru Tsuruoka, Takamitsu Morioka, Mayumi Shinagawa, Mari Ogawa, Yoshiya Shimada, Akira Tachibana, Daisuke Iizuka, Shizuko Kakinuma
Publikováno v:
Biology, Vol 11, Iss 3, p 449 (2022)
The risk of radiation-induced carcinogenesis depends on age at exposure. We previously reported principal causative genes in lymphomas arising after infant or adult exposure to 4-fractionated irradiation as Pten or Ikzf1, respectively, suggesting tha
Externí odkaz:
https://doaj.org/article/34d20e1ece824a28b25eaefa2a5f640a
Autor:
Masaru Takabatake, Benjamin J Blyth, Kazuhiro Daino, Tatsuhiko Imaoka, Mayumi Nishimura, Masahiro Fukushi, Yoshiya Shimada
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164194 (2016)
Several lines of evidence indicate one's age at exposure to radiation strongly modifies the risk of radiation-induced breast cancer. We previously reported that rat mammary carcinomas induced by pre- and post-pubertal irradiation have distinct gene e
Externí odkaz:
https://doaj.org/article/e16ff4143a364e40b9e5fdeb7b040cab
Autor:
Benjamin J Blyth, Shizuko Kakinuma, Masaaki Sunaoshi, Yoshiko Amasaki, Shinobu Hirano-Sakairi, Kanae Ogawa, Ayana Shirakami, Yi Shang, Chizuru Tsuruoka, Mayumi Nishimura, Yoshiya Shimada
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0130666 (2015)
Monitoring mice exposed to carbon ion radiotherapy provides an indirect method to evaluate the potential for second cancer induction in normal tissues outside the radiotherapy target volume, since such estimates are not yet possible from historical p
Externí odkaz:
https://doaj.org/article/e95c58c780cf4c2fb5189b0c3629c6e8
Autor:
Paul N. Schofield, Atsuro Ishida, Bernd Grosche, Yutaka Yamada, Takeo Shimomura, Takamitsu Morioka, Benjamin J. Blyth, Jun Ohtake, Tatsuhiko Imaoka, Shizuko Kakinuma, Yoshiya Shimada, Mayumi Nishimura, Ulrike Kulka, Hiroshi Takeshita
Publikováno v:
International Journal of Radiation Biology. 95:1372-1377
Purpose: Projects evaluating the effects of radiation, within the National Institutes of Quantum and Radiological Science and Technology (QST), National Institute of Radiological Sciences (...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4de1a43c410155549e8607650350aa32
https://doi.org/10.1080/09553002.2019.1625458
https://doi.org/10.1080/09553002.2019.1625458
The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
Autor:
Magnus Zethoven, Conor J. Kearney, Matteo Costacurta, Izabela Todorovski, Alessandro Gardini, Michael Ohlmeyer, Stefan Bjelosevic, Gareth P. Gregory, Deborah A. Knight, Nathanael S. Gray, Jarrod J. Sandow, Sarah A. Welsh, Elisa Barbieri, Andrea Newbold, Madison J. Kelly, Otto Kauko, Sarah Offley, Joseph H.A. Vissers, Benjamin J. Blyth, Stephin J. Vervoort, Kaylene J. Simpson, Ben P. Martin, Ricky W. Johnstone, Jukka Westermarck, Jennifer R. Devlin, Kieran F. Harvey, Karolina Pavic, Edwin D. Hawkins, Elena Demosthenous, Isabella Y. Kong, Zheng Fan, Victoria McLeod, Simon J. Hogg
Publikováno v:
Cell
Gene expression by RNA polymerase II (RNAPII) is tightly controlled by cyclin-dependent kinases (CDKs) at discrete checkpoints during the transcription cycle. The pausing checkpoint following transcription initiation is primarily controlled by CDK9.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f96a12e3df6259f7ff40c0a9115141a
https://europepmc.org/articles/PMC8567840/
https://europepmc.org/articles/PMC8567840/
Autor:
Michelle R Newman, Pamela J Sykes, Benjamin J Blyth, Eva Bezak, Mark D Lawrence, Katherine L Morel, Rebecca J Ormsby
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e93016 (2014)
The low dose radioadaptive response has been shown to be protective against high doses of radiation as well as aging-induced genomic instability. We hypothesised that a single whole-body exposure of low dose radiation would induce a radioadaptive res
Externí odkaz:
https://doaj.org/article/10f73dd7fbf6424fbe5b968e2d02ddb6
Autor:
Lachlan E, McInnes, Carleen, Cullinane, Peter D, Roselt, Susan, Jackson, Benjamin J, Blyth, Ellen M, van Dam, Nicholas A, Zia, Matthew J, Harris, Rodney J, Hicks, Paul S, Donnelly
Publikováno v:
J Nucl Med
Radionuclide therapy targeting prostate-specific membrane antigen (PSMA) is promising for prostate cancer. We previously reported a ligand, (64)Cu-CuSarbisPSMA, featuring 2 lysine-ureido-glutamate groups. Here, we report the therapeutic potential of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::e08fa07b08a6a14f0fe44bd798aba0ae
https://pubmed.ncbi.nlm.nih.gov/33067341
https://pubmed.ncbi.nlm.nih.gov/33067341