Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Benjamin I Baarda"'
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007385 (2019)
The six-component maintenance of lipid asymmetry (Mla) system is responsible for retrograde transport of phospholipids, ensuring the barrier function of the Gram-negative cell envelope. Located within the outer membrane, MlaA (VacJ) acts as a channel
Externí odkaz:
https://doaj.org/article/14c1fa4f9bab45fc98d6a245e542a0c8
Autor:
Ryszard A Zielke, Adriana Le Van, Benjamin I Baarda, Marco F Herrera, Christopher J Acosta, Ann E Jerse, Aleksandra E Sikora
Publikováno v:
PLoS Pathogens, Vol 14, Iss 7, p e1007081 (2018)
Lysozymes are nearly omnipresent as the first line of immune defense against microbes in animals. They exert bactericidal action through antimicrobial peptide activity and peptidoglycan hydrolysis. Gram-negative bacteria developed several weapons to
Externí odkaz:
https://doaj.org/article/ac19f9d4042448a5b91e286e362a1563
Publikováno v:
Frontiers in Microbiology, Vol 6 (2015)
Neisseria gonorrhoeae is an exquisitely adapted, strictly human pathogen and the causative agent of the sexually transmitted infection gonorrhea. This ancient human disease remains a serious problem, occurring at high incidence globally and having a
Externí odkaz:
https://doaj.org/article/00489fb22f564a27971619ba82a99ee4
Publikováno v:
mSphere, Vol 6, Iss 1 (2021)
Neisseria gonorrhoeaeN. gonorrhoeaeN. gonorrhoeae
Externí odkaz:
https://doaj.org/article/ea0991a52a074f10ad55b87d80f171f7
Publikováno v:
Frontiers in Microbiology, Vol 9 (2018)
Lipid-modified cupredoxin azurin (Laz) is involved in electron transport in Neisseria and proposed to act as an electron donor to the surface-displayed nitrite reductase AniA. We identified Laz in Neisseria gonorrhoeae cell envelopes and naturally el
Externí odkaz:
https://doaj.org/article/2666fd5fd9e340b59db1f73888b72900
Publikováno v:
mSphere, Vol 6, Iss 1 (2021)
mSphere
mSphere
Neisseria gonorrhoeae, the Gram-negative bacterium responsible for the sexually transmitted infection gonorrhea, is categorized as a high-priority pathogen for research and development efforts. N. gonorrhoeae’s “superbug” status, its high morbi
Autor:
Adriana Le Van, Benjamin I. Baarda, Stephen C. Darnell, Fabian G. Martinez, Ryszard A. Zielke, Carolina Gomez, Josephine A. Bonventre, Aleksandra E. Sikora, Ann E. Jerse
Publikováno v:
Vaccine
Bacterial surface lipoproteins are emerging as attractive vaccine candidates due to their biological importance and the feasibility of their large-scale production for vaccine manufacturing. The global prevalence of gonorrhea, resistance to antibioti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a3e3c062a70b7eae3aba526b189d881
https://doi.org/10.1101/2020.06.19.161646
https://doi.org/10.1101/2020.06.19.161646
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 1997
Phenotype MicroArrays (PMs) provide a considerable benefit to the evaluation of potential vaccine/drug targets and the assessment of hypothetical protein function. Nearly 2000 conditions can be screened relatively quickly either to search for phenoty
Publikováno v:
Neisseria gonorrhoeae ISBN: 9781493994953
Phenotype MicroArrays (PMs) provide a considerable benefit to the evaluation of potential vaccine/drug targets and the assessment of hypothetical protein function. Nearly 2000 conditions can be screened relatively quickly either to search for phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aceae5c1bb746d9e9bdb69187757a4a3
https://doi.org/10.1007/978-1-4939-9496-0_13
https://doi.org/10.1007/978-1-4939-9496-0_13
Autor:
Benjamin I. Baarda, King K. Holmes, Ryszard A. Zielke, Aleksandra E. Sikora, Magnus Unemo, Igor H. Wierzbicki, Olusegun O. Soge, Ann E. Jerse, Philip R. Gafken
Publikováno v:
Molecular & Cellular Proteomics. 15:2338-2355
Expanding efforts to develop preventive gonorrhea vaccines is critical because of the dire possibility of untreatable gonococcal infections. Reverse vaccinology, which includes genome and proteome mining, has proven very successful in the discovery o