Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Benjamin I . Laufer"'
Autor:
Annie Vogel Ciernia, Benjamin I . Laufer, Keith W. Dunaway, Charles E. Mordaunt, Rochelle L. Coulson, Theresa S. Totah, Danielle S. Stolzenberg, Jaime C. Frahm, Akanksha Singh-Taylor, Tallie Z. Baram, Janine M. LaSalle, Dag H. Yasui
Publikováno v:
Epigenetics, Vol 13, Iss 3, Pp 318-330 (2018)
Augmented maternal care during the first postnatal week promotes life-long stress resilience and improved memory compared with the outcome of routine rearing conditions. Recent evidence suggests that this programming commences with altered synaptic c
Externí odkaz:
https://doaj.org/article/227c1ee5f52246338f871058fd440733
Autor:
Yihui Zhu, J. Antonio Gomez, Benjamin I. Laufer, Charles E. Mordaunt, Julia S. Mouat, Daniela C. Soto, Megan Y. Dennis, Kelly S. Benke, Kelly M. Bakulski, John Dou, Ria Marathe, Julia M. Jianu, Logan A. Williams, Orangel J. Gutierrez Fugón, Cheryl K. Walker, Sally Ozonoff, Jason Daniels, Luke P. Grosvenor, Heather E. Volk, Jason I. Feinberg, M. Daniele Fallin, Irva Hertz-Picciotto, Rebecca J. Schmidt, Dag H. Yasui, Janine M. LaSalle
Publikováno v:
Genome Biology, Vol 23, Iss 1, Pp 1-32 (2022)
Abstract Background Autism spectrum disorder (ASD) involves complex genetics interacting with the perinatal environment, complicating the discovery of common genetic risk. The epigenetic layer of DNA methylation shows dynamic developmental changes an
Externí odkaz:
https://doaj.org/article/f6d35ff30916481bbb358c37ec11e956
Autor:
Angela G. Maggio, Henry T. Shu, Benjamin I. Laufer, Chongfeng Bi, Yinglei Lai, Janine M. LaSalle, Valerie W. Hu
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Environmental exposures to endocrine disrupting compounds (EDCs) such as the organochlorines have been linked with various diseases including neurodevelopmental disorders. Autism spectrum disorder (ASD) is a highly complex neurodevelopmental disorder
Externí odkaz:
https://doaj.org/article/4049fdc39ba74dbcb2ae582372ba4402
Autor:
Charles E. Mordaunt, Julia M. Jianu, Benjamin I. Laufer, Yihui Zhu, Hyeyeon Hwang, Keith W. Dunaway, Kelly M. Bakulski, Jason I. Feinberg, Heather E. Volk, Kristen Lyall, Lisa A. Croen, Craig J. Newschaffer, Sally Ozonoff, Irva Hertz-Picciotto, M. Daniele Fallin, Rebecca J. Schmidt, Janine M. LaSalle
Publikováno v:
Genome Medicine, Vol 12, Iss 1, Pp 1-25 (2020)
Abstract Background Autism spectrum disorder (ASD) is a neurodevelopmental disorder with complex heritability and higher prevalence in males. The neonatal epigenome has the potential to reflect past interactions between genetic and environmental fact
Externí odkaz:
https://doaj.org/article/5daab9d3cbe4415ca5f185f325d2a213
Publikováno v:
Environment International, Vol 158, Iss , Pp 106993- (2022)
Background: Wildfire smoke is responsible for around 20% of all particulate emissions in the U.S. and affects millions of people worldwide. Children are especially vulnerable, as ambient air pollution exposure during early childhood is associated wit
Externí odkaz:
https://doaj.org/article/77cc765134bf4124830d3738f9a98a99
Autor:
Amy E. Byrnes, Sara L. Dominguez, Chun-Wan Yen, Benjamin I. Laufer, Oded Foreman, Mike Reichelt, Han Lin, Meredith Sagolla, Kathy Hötzel, Hai Ngu, Christoffer Soendergaard, Alberto Estevez, Hsiu-Chao Lin, Alexandre Goyon, Juan Bian, Jessica Lin, Flora I. Hinz, Brad A. Friedman, Amy Easton, Casper C. Hoogenraad
Publikováno v:
Molecular Therapy - Nucleic Acids. 32:773-793
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c8a70dd7c7923981b42d6554597a87f6
https://doi.org/10.1016/j.omtn.2023.05.005
https://doi.org/10.1016/j.omtn.2023.05.005
Autor:
Rochelle L. Coulson, Dag H. Yasui, Keith W. Dunaway, Benjamin I. Laufer, Annie Vogel Ciernia, Yihui Zhu, Charles E. Mordaunt, Theresa S. Totah, Janine M. LaSalle
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-11 (2018)
Many genes have oscillating gene expression pattern in circadian centers of the brain. This study shows cortical diurnal DNA methylation oscillation in a mouse model of Prader-Willi syndrome, and describes corresponding changes in gene expression and
Externí odkaz:
https://doaj.org/article/d481882ef53445478adf7400b2b40b3f
Autor:
Julia S. Mouat, Shaobo Li, Swe Swe Myint, Benjamin I. Laufer, Philip J. Lupo, Jeremy M. Schraw, John P. Woodhouse, Adam J. de Smith, Janine M. LaSalle
Publikováno v:
medRxiv
BackgroundCongenital heart defects(CHDs)affect approximately half of individuals with Down syndrome(DS)but the molecular reasons for incomplete penetrance are unknown. Previous studies have largely focused on identifying genetic risk factors associat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef3bee197c7f5d3cf8f95d5be4bab06c
https://europepmc.org/articles/PMC10187438/
https://europepmc.org/articles/PMC10187438/
Autor:
Min Jung, Michelle Dourado, James Maksymetz, Amanda Jacobson, Benjamin I. Laufer, Miriam Baca, Oded Foreman, David H. Hackos, Lorena Riol-Blanco, Joshua S. Kaminker
Publikováno v:
Nature Communications. 14
Sensory neurons of the dorsal root ganglion (DRG) are critical for maintaining tissue homeostasis by sensing and initiating responses to stimuli. While most preclinical studies of DRGs are conducted in rodents, much less is known about the mechanisms
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a375bf6eb52ed5227126ec22edb90c72
https://doi.org/10.1038/s41467-023-36014-0
https://doi.org/10.1038/s41467-023-36014-0
Autor:
Benjamin I. Laufer, Yu Hasegawa, Zhichao Zhang, Casey E. Hogrefe, Laura A. Del Rosso, Lori Haapanen, Hyeyeon Hwang, Melissa D. Bauman, Judy Van de Water, Ameer Y. Taha, Carolyn M. Slupsky, Mari S. Golub, John P. Capitanio, Catherine A. VandeVoort, Cheryl K. Walker, Janine M. LaSalle
Publikováno v:
Nature communications, vol 13, iss 1
Maternal obesity during pregnancy is associated with neurodevelopmental disorder (NDD) risk. We utilized integrative multi-omics to examine maternal obesity effects on offspring neurodevelopment in rhesus macaques by comparison to lean controls and t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd27be798bfefe09491463411a1fabf
https://escholarship.org/uc/item/8sz235rb
https://escholarship.org/uc/item/8sz235rb