Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Benjamin H. Lee"'
Autor:
Nina L. Cluny, Kewir D. Nyuyki, Wagdi Almishri, Lateece Griffin, Benjamin H. Lee, Simon A. Hirota, Quentin J. Pittman, Mark G. Swain, Keith A. Sharkey
Publikováno v:
Journal of Neuroinflammation, Vol 19, Iss 1, Pp 1-17 (2022)
Abstract Background Behavioral comorbidities, such as anxiety and depression, are a prominent feature of IBD. The signals from the inflamed gut that cause changes in the brain leading to these behavioral comorbidities remain to be fully elucidated. W
Externí odkaz:
https://doaj.org/article/ef43bce9d5ca482a970897fdee876d16
Autor:
Shaona Acharjee, Paul M. K. Gordon, Benjamin H. Lee, Justin Read, Matthew L. Workentine, Keith A. Sharkey, Quentin J. Pittman
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Microglia play an important role in the pathogenesis of multiple sclerosis and the mouse model of MS, experimental autoimmune encephalomyelitis (EAE). To more fully understand the role of microglia in EAE we characterized microglial transcri
Externí odkaz:
https://doaj.org/article/3d560b4984894d3a9e47097a0d613700
Autor:
Yu Yang, Ricard Masia, Yue Ren, Benjamin H Lee, Jonathan A Hill, Vito J Palombella, Karin Golan
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/a3a6f23fedec436288bbf68f16c6d31d
Autor:
Michael C. Warren, Stephan Matissek, Matthew Rausch, Marisella Panduro, R. J. Hall, Austin Dulak, David Brennan, Sonia Das Yekkirala, Secil Koseoglu, Ricard Masia, Yu Yang, Navamallika Reddy, Robert Prenovitz, Jamie Strand, Tauqueer Zaidi, Erik Devereaux, Célia Jacoberger Foissac, John Stagg, Benjamin H. Lee, Pamela Holland, Vito J. Palombella, Andrew C. Lake
Publikováno v:
ImmunoHorizons. 7:366-379
CD39 (ENTPD1) is a key enzyme responsible for degradation of extracellular ATP and is upregulated in the tumor microenvironment (TME). Extracellular ATP accumulates in the TME from tissue damage and immunogenic cell death, potentially initiating proi
Autor:
Alan Huang, Robert Schlegel, Andrew X. Zhu, Dalila Sellami, Benjamin H. Lee, Yan Wang, Michael R. Palmer, Marissa N. Balak, Adnan Derti, Manway Liu, David Ruddy, David Yang, Panisa Pochanard, Khee Chee Soo, Richard Ong, David Chen, Stephen L. Chan, Huai-Xiang Hao, Hung Huynh
TSC2 immunohistochemistry assay validation and analysis of HCC xenograft and primary tumors. (A) TSC2 immunohistochemistry (IHC) assay with HCC cell lines. (B) TSC2 IHC assay with HCC xenograft tumors. (C) TSC2 expression by IHC assay in HCC xenograf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aed707968e08cedb046e582fea806972
https://doi.org/10.1158/1535-7163.22501840.v1
https://doi.org/10.1158/1535-7163.22501840.v1
Autor:
Alan Huang, Robert Schlegel, Andrew X. Zhu, Dalila Sellami, Benjamin H. Lee, Yan Wang, Michael R. Palmer, Marissa N. Balak, Adnan Derti, Manway Liu, David Ruddy, David Yang, Panisa Pochanard, Khee Chee Soo, Richard Ong, David Chen, Stephen L. Chan, Huai-Xiang Hao, Hung Huynh
Race distribution of HCC patients in EVOLVE-1 trial. Percentage of Caucasian, Asian and other race in different groups of EVOLVE-1 patients (A) and TSC2 IHC H-score ranges (B).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f2dedd4f7c3ff0dc17d2b0d9e378d03
https://doi.org/10.1158/1535-7163.22501837.v1
https://doi.org/10.1158/1535-7163.22501837.v1
Autor:
Alan Huang, Robert Schlegel, Andrew X. Zhu, Dalila Sellami, Benjamin H. Lee, Yan Wang, Michael R. Palmer, Marissa N. Balak, Adnan Derti, Manway Liu, David Ruddy, David Yang, Panisa Pochanard, Khee Chee Soo, Richard Ong, David Chen, Stephen L. Chan, Huai-Xiang Hao, Hung Huynh
Mechanisms of TSC2 loss in HCC cell lines and xenografts. (A) Taqman RT-PCR analysis of TSC1 and TSC2 mRNA levels in HCC cell lines. (B) Taqman RT-PCR analysis of MZB1, TSC1 and TSC2 mRNA levels in TSC2-null Li-7 cells treated with epigenetic inhibit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::837643276feb900f95b1eb9624af0fc2
https://doi.org/10.1158/1535-7163.22501843
https://doi.org/10.1158/1535-7163.22501843
Autor:
Alan Huang, Robert Schlegel, Andrew X. Zhu, Dalila Sellami, Benjamin H. Lee, Yan Wang, Michael R. Palmer, Marissa N. Balak, Adnan Derti, Manway Liu, David Ruddy, David Yang, Panisa Pochanard, Khee Chee Soo, Richard Ong, David Chen, Stephen L. Chan, Huai-Xiang Hao, Hung Huynh
Genetic characterization of 35 established HCC PTX models by targeted DNA sequencing (Excel file).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cd02edc563b72a5db23f4cdd2e51e9d
https://doi.org/10.1158/1535-7163.22501828.v1
https://doi.org/10.1158/1535-7163.22501828.v1
Autor:
Alan Huang, Robert Schlegel, Andrew X. Zhu, Dalila Sellami, Benjamin H. Lee, Yan Wang, Michael R. Palmer, Marissa N. Balak, Adnan Derti, Manway Liu, David Ruddy, David Yang, Panisa Pochanard, Khee Chee Soo, Richard Ong, David Chen, Stephen L. Chan, Huai-Xiang Hao, Hung Huynh
Supplementary Table 1. Quantification of phospho-protein levels in Figure 1B. Supplementary Table 2. Everolimus IC50 and growth inhibition at 1uM in HCC cell lines. Supplementary Table 3. Quantification of phospho-protein levels in Figure 2A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b17aa04e4ad76b69e1e5cb89fc2c088b
https://doi.org/10.1158/1535-7163.22501831.v1
https://doi.org/10.1158/1535-7163.22501831.v1
Autor:
Alan Huang, Robert Schlegel, Andrew X. Zhu, Dalila Sellami, Benjamin H. Lee, Yan Wang, Michael R. Palmer, Marissa N. Balak, Adnan Derti, Manway Liu, David Ruddy, David Yang, Panisa Pochanard, Khee Chee Soo, Richard Ong, David Chen, Stephen L. Chan, Huai-Xiang Hao, Hung Huynh
TSC2 loss in HCC cell lines leads to mTOR activation. (A) Reverse Phase Protein Array (RPPA) analysis of nine HCC cell lines for TSC2 protein levels and phosphorylation levels of S6K1, 4E-BP1, S6 and AKT. (B) Immunoblot of TSC2 wild-type HuH-7 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b680657ba6cbc6b4ece80d22c0e003f
https://doi.org/10.1158/1535-7163.22501846
https://doi.org/10.1158/1535-7163.22501846