Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Benjamin H. Gern"'
Autor:
Sara B. Cohen, Courtney R. Plumlee, Lindsay Engels, Dat Mai, Tara A. Murray, Ana N. Jahn, Bridget Alexander, Jared L. Delahaye, Lauren M. Cross, Karolina Maciag, Sam Schrader, Kaitlin Durga, Elizabeth S. Gold, Alan Aderem, Michael Y. Gerner, Benjamin H. Gern, Alan H. Diercks, Kevin B. Urdahl
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
To investigate how host and pathogen diversity govern immunity against Mycobacterium tuberculosis (Mtb), we performed a large-scale screen of vaccine-mediated protection against aerosol Mtb infection using three inbred mouse strains [C57BL/6 (B6), C3
Externí odkaz:
https://doaj.org/article/8f1d5d9be6814725a222414224aa913c
Autor:
Caleb R. Stoltzfus, Jakub Filipek, Benjamin H. Gern, Brandy E. Olin, Joseph M. Leal, Yajun Wu, Miranda R. Lyons-Cohen, Jessica Y. Huang, Clarissa L. Paz-Stoltzfus, Courtney R. Plumlee, Thomas Pöschinger, Kevin B. Urdahl, Mario Perro, Michael Y. Gerner
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp - (2020)
Summary: Recently developed approaches for highly multiplexed imaging have revealed complex patterns of cellular positioning and cell-cell interactions with important roles in both cellular- and tissue-level physiology. However, tools to quantitative
Externí odkaz:
https://doaj.org/article/1df5a2d1e3124838b0964fff24a70671
Autor:
Benjamin H. Gern, Alexander L. Greninger, Scott J. Weissman, Jennifer R. Stapp, Yue Tao, Xuan Qin
Publikováno v:
Annals of Clinical Microbiology and Antimicrobials, Vol 17, Iss 1, Pp 1-5 (2018)
Abstract Objectives In vitro trends of cefazolin and ceftriaxone susceptibilities from pediatric clinical isolates of methicillin-susceptible Staphylococcus aureus (MSSA) between 2011 and 2016 were analyzed for surveillance. Methods Our laboratory co
Externí odkaz:
https://doaj.org/article/d48209326f8d487788eb492ff9bcaa4a
Publikováno v:
Annual review of immunology. 40
Pulmonary granulomas are widely considered the epicenters of the immune response to Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB). Recent animal studies have revealed factors that either promote or restrict TB immunity wi
Autor:
Shahin Shafiani, Kevin B. Urdahl, Michael Y. Gerner, Benjamin H. Gern, Jared L. Delahaye, Sara B. Cohen, Courtney R. Plumlee
Publikováno v:
The Journal of Immunology. 203:807-812
Growing evidence suggests the outcome of Mycobacterium tuberculosis infection is established rapidly after exposure, but how the current tuberculosis vaccine, bacillus Calmette–Guérin (BCG), impacts early immunity is poorly understood. In this stu
Autor:
Michael Y. Gerner, Mario Perro, Caleb R. Stoltzfus, Thomas Pöschinger, Brandy E. Olin, Clarissa L. Paz-Stoltzfus, Courtney R. Plumlee, Joseph M. Leal, Yajun Wu, Jakub Filipek, Benjamin H. Gern, Jessica Y. Huang, Miranda R. Lyons-Cohen, Kevin B. Urdahl
Publikováno v:
Cell Reports, Vol 31, Iss 3, Pp-(2020)
Cell reports
Cell reports
SUMMARY Recently developed approaches for highly multiplexed imaging have revealed complex patterns of cellular positioning and cell-cell interactions with important roles in both cellular- and tissue-level physiology. However, tools to quantitativel
Autor:
Kristin N. Adams, Jacob D. Estes, Scott G. Hansen, Laila Shehata, Kathleen Busman-Sahay, Louis J. Picker, Michael K. Axthelm, Courtney R. Plumlee, Kevin B. Urdahl, Benjamin H. Gern, Caleb R. Stoltzfus, Albanus O. Moguche, Michael Y. Gerner
Publikováno v:
Cell Host Microbe
CD4 T cell effector function, including IFNγ production, is required for optimal containment of Mycobacterium tuberculosis (Mtb) infection. Despite this, lung-infiltrating CD4 T cells have a relatively limited ability to produce IFNγ, which plays a
Autor:
Tige R. Rustad, Courtney R. Plumlee, John D. Aitchison, David R. Sherman, Michael K. Axthelm, Vitaly V. Ganusov, Sara B. Cohen, Caleb R. Stoltzfus, Benjamin H. Gern, Michael Y. Gerner, Fergal J. Duffy, Kevin B. Urdahl, Daniel E. Zak, Scott G. Hansen, Jared L. Delahaye, Louis J. Picker
Publikováno v:
SSRN Electronic Journal.
Tuberculosis (TB) is a highly heterogeneous disease that develops in a subset of individuals infected with aerosolized Mycobacterium tuberculosis (Mtb). We sought to develop an improved experimental model by infecting mice with an ultra-low dose (ULD
Autor:
Jacob D. Estes, Laila Shehata, Kathleen Busman-Sahay, Benjamin H. Gern, Kristin N. Adams, Michael Y. Gerner, Scott G. Hansen, Caleb R. Stoltzfus, Albanus O. Moguche, Louis J. Picker, Michael K. Axthelm, Courtney R. Plumlee, Kevin B. Urdahl
Publikováno v:
SSRN Electronic Journal.
Interferon gamma (IFNɣ) produced by CD4 T cells is required for immune containment of Mycobacterium tuberculosis (Mtb) infection. Despite this, IFNɣ plays a minor role in CD4 T cell- mediated immunity within the lung. In this study, we use a recent
Autor:
Michael Y. Gerner, Clarissa L. Paz-Stoltzfus, Miranda R. Lyons-Cohen, Jessica Huang, Thomas Pöschinger, Mario Perro, Benjamin H. Gern, Kevin B. Urdahl, Caleb R. Stoltzfus, Courtney R. Plumlee, Jakub Filipek, Brandy E. Olin, Joseph M. Leal
Recently developed approaches for highly-multiplexed 2-dimensional (2D) and 3D imaging have revealed complex patterns of cellular positioning and cell-cell interactions with important roles in both cellular and tissue level physiology. However, robus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66fab61bf1d328a7b72a72f3b31344a9
https://doi.org/10.1101/769877
https://doi.org/10.1101/769877