Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Benjamin H. Fraser"'
Autor:
Giancarlo Pascali, Lidia Matesic, Bo Zhang, Andrew T. King, Andrea J. Robinson, Alison T. Ung, Benjamin H. Fraser
Publikováno v:
EJNMMI Radiopharmacy and Chemistry, Vol 2, Iss 1, Pp 1-18 (2017)
Abstract The importance of the sulfur-fluorine bond is starting to increase in modern medicinal chemistry literature. This is due to a better understanding of the stability and reactivity of this moiety depending on the various oxidation states of su
Externí odkaz:
https://doaj.org/article/b088fac7e1fb42128c51b0dc02f1700e
Publikováno v:
Nuclear Medicine and Biology. :112-147
The deuterium labelling of pharmaceuticals is a useful strategy for altering pharmacokinetic properties, particularly for improving metabolic resistance. The pharmacological effects of such metabolites are often assumed to be negligible during standa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73530c2a11a90614086e496f2ed53235
https://doi.org/10.1016/j.nucmedbio.2021.03.011
https://doi.org/10.1016/j.nucmedbio.2021.03.011
Publikováno v:
Chemistry – A European Journal. 27:861-876
Positron emission tomography (PET)-fluorescence imaging is an emerging field of multimodality imaging seeking to attain synergy between the two techniques. The probes employed in PET-fluorescence imaging incorporate both a fluorophore and radioisotop
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47094e8297b113a883edb0ee5267cf27
https://doi.org/10.1002/chem.202001402
https://doi.org/10.1002/chem.202001402
Autor:
Giancarlo Pascali, Massimiliano Massi, Benjamin H. Fraser, Vaughan Moon, Mitchell A. Klenner, Brendan J. Evans
Publikováno v:
European Journal of Inorganic Chemistry. 2020:3554-3564
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::381e463c76fcd5ff978754b11a4bab22
https://doi.org/10.1002/ejic.202000433
https://doi.org/10.1002/ejic.202000433
Autor:
Massimiliano Massi, Benjamin H. Fraser, Tamim A. Darwish, Mitchell A. Klenner, Giancarlo Pascali
Publikováno v:
Organometallics. 39:2334-2351
While radiopharmaceuticals incorporating rhenium-188 or rhenium-186 radioisotopes have been well documented in the literature, the labeling of rhenium complexes with alternative isotopes has receiv...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc74cff0334b17520efb1bd14c8875dd
https://doi.org/10.1021/acs.organomet.0c00267
https://doi.org/10.1021/acs.organomet.0c00267
Autor:
David StC. Black, Naresh Kumar, Jeremy C. Dobrowolski, Mohan M. Bhadbhade, Duyen H. T. Nguyen, Benjamin H. Fraser
Publikováno v:
Synlett. 30:2081-2085
A new class of heterocyclic compounds, namely the benzoazepinoindolones, has been synthesised through a base-catalysed cyclisation reaction of 1,4-bis(2-aminophenyl)-2-phenylbutane-1,4-dione derivatives and features the prominent seven-membered azepi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::817bf49cb4f647d052fdbec7d3beaab9
https://doi.org/10.1055/s-0039-1690700
https://doi.org/10.1055/s-0039-1690700
Autor:
Steven H. Liang, Benjamin H. Fraser, Zhen Chen, Massimiliano Massi, Andrea J. Robinson, Bo Zhang, Mitchell A. Klenner, Giancarlo Pascali
Publikováno v:
Chemistry – A European Journal. 25:7613-7617
Fluorine-18 is the most utilized radioisotope in positron emission tomography (PET), but the wide application of fluorine-18 radiopharmaceuticals is hindered by its challenging labelling conditions. As such, many potentially important radiotracers re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb59b7c4fad9ae61d9baee86ba94a11c
https://doi.org/10.1002/chem.201900930
https://doi.org/10.1002/chem.201900930
Autor:
Duyen H. T. Nguyen, Jeremy C. Dobrowolski, Benjamin H. Fraser, Naresh Kumar, Mohan M. Bhadbhade, David StC. Black
Publikováno v:
Synlett. 30:567-572
Complex benzazepinoquinolone scaffolds can be accessed from the reaction of 2-aminoacetophenones and oxindole derivatives and feature the seven-membered azepine ring moiety commonly found in a range of drug molecules. The described reaction is genera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::086e22315bae3de0803470693dccd89b
https://doi.org/10.1055/s-0037-1612106
https://doi.org/10.1055/s-0037-1612106
Autor:
Benjamin H. Fraser, Anwen M. Krause-Heuer, Lynette C. Daws, Mohamed S. Basiouny, Ivan Greguric, Naresh Kumar, Harald H. Sitte, Maxine P. Roberts, Naomi Wyatt, Wouter Koek, Jeremy C. Dobrowolski, Felix P. Mayer, Rheaclare Fraser-Spears, Paul D. Callaghan, Retrouvailles Manishimwe
Publikováno v:
European Journal of Pharmacology. 842:351-364
Growing evidence supports involvement of low-affinity/high-capacity organic cation transporters (OCTs) and plasma membrane monoamine transporter (PMAT) in regulating clearance of monoamines. Currently decynium-22 (D22) is the best pharmacological too
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da7fbf0d4b1e9fc9bd6140790fa7b32
https://doi.org/10.1016/j.ejphar.2018.10.028
https://doi.org/10.1016/j.ejphar.2018.10.028
Publikováno v:
Chemistry – A European Journal. 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73c13a3074defa540bf76ee63b3f8cc4
https://doi.org/10.1002/chem.202180362
https://doi.org/10.1002/chem.202180362