Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Benjamin H, Opot"'
Autor:
Frederik Von Wowern, Geofrey Makenga, Sarah Wellmann Thomsen, Louise Wellmann Thomsen, Emma Filtenborg Hocke, Vito Baraka, Benjamin H. Opot, Daniel T.R. Minja, John P.A. Lusingu, Jean-Pierre Van-geertruyden, Helle Hansson, Michael Alifrangis
Publikováno v:
International Journal of Infectious Diseases, Vol 146, Iss , Pp 107102- (2024)
Objective: Intermittent Preventive Treatment of schoolchildren (IPTsc) is recommended by WHO as a strategy to protect against malaria; to explore whether IPTsc with dihydroartemisinin-piperaquine (DP) or artesunate-amodiaquine (ASAQ) cause a selectio
Externí odkaz:
https://doaj.org/article/abe4b30ff83545ca8a7b4b590155b130
Autor:
Gladys C. Chemwor, Ben M. Andagalu, Irene A. Onyango, Benjamin H. Opot, Raphael O. Okoth, Redemptah A. Yedah, Jackline A. Juma, Edwin W. Mwakio, Dancan M. Wakoli, Joseph G. Amwoma, Agnes C. Cheruiyot, Dennis W. Juma, Bernhards R. Ogutu, Timothy E. Egbo, Eric C. Garges, Amanda L. Roth, Edwin Kamau, Oliver J. Watson, Hoseah M. Akala
Publikováno v:
International Journal of Infectious Diseases, Vol 132, Iss , Pp 17-25 (2023)
Objectives: This study examined the treatment response of mixed vs single-species Plasmodium falciparum infections to artemisinin-based combination therapies (ACTs). Methods: A total of 1211 blood samples collected on days 0, 7, 14, 21, 28, 35, and 4
Externí odkaz:
https://doaj.org/article/d19083ff7cf44a0d9b137282179c1b84
Autor:
Winnie Okore, Collins Ouma, Raphael O Okoth, Redemptah Yeda, Luicer O Ingasia, Edwin W Mwakio, Douglas O Ochora, Duncan M Wakoli, Joseph G Amwoma, Gladys C Chemwor, Jackline A Juma, Charles O Okudo, Agnes C Cheruiyot, Benjamin H Opot, Dennis Juma, Timothy E Egbo, Ben Andagalu, Amanda Roth, Edwin Kamau, Hoseah M Akala
Publikováno v:
PLoS ONE, Vol 19, Iss 6, p e0298585 (2024)
Single nucleotide polymorphisms (SNPs) in the Plasmodium falciparum multi-drug resistance protein 1 (Pfmrp1) gene have previously been reported to confer resistance to Artemisinin-based Combination Therapies (ACTs) in Southeast Asia. A total of 300 s
Externí odkaz:
https://doaj.org/article/3552aaa210124c479cb095b7b88701bf
Autor:
Dancan M. Wakoli, Bartholomew N. Ondigo, Douglas O. Ochora, Joseph G. Amwoma, Winnie Okore, Edwin W. Mwakio, Gladys Chemwor, Jackeline Juma, Raphael Okoth, Charles Okudo, Redemptah Yeda, Benjamin H. Opot, Agnes C. Cheruiyot, Dennis Juma, Amanda Roth, Benhards R. Ogutu, Daniel Boudreaux, Ben Andagalu, Hoseah M. Akala
Publikováno v:
BMC Medicine, Vol 20, Iss 1, Pp 1-15 (2022)
Abstract Background Dihydroartemisinin-piperaquine (DHA-PPQ) is an alternative first-line antimalarial to artemether-lumefantrine in Kenya. However, recent reports on the emergence of PPQ resistance in Southeast Asia threaten its continued use in Ken
Externí odkaz:
https://doaj.org/article/f4342a5daf924e1da218017f3888927d
Autor:
Dennis W. Juma, Benjamin H. Opot, Hosea M. Akala, Amanda L. Roth, Ben M. Andagalu, Jennifer M. Mutisya, Johnson K. Kinyua, Victor A. Mobegi, Raphael O. Okoth, Martha N. Kivecu, Edwin W. Mwakio, Gladys C. Chemwor, Redempta A. Yeda, Agnes C. Cheruiyot, Jackline A. Juma, Charles O. Okello
Publikováno v:
F1000Research, Vol 9 (2022)
Background: The emergence of artemisinin resistance in South East Asia calls for urgent discovery of new drug compounds that have antiplasmodial activity. Unlike the classical compound screening drug discovery methods, the rational approach involving
Externí odkaz:
https://doaj.org/article/3bfdfb6ffe72483bbaeeac0f7421e1cf
Autor:
Angela O. Achieng, Peninah Muiruri, Luicer A. Ingasia, Benjamin H. Opot, Dennis W. Juma, Redemptah Yeda, Bidii S. Ngalah, Bernhards R. Ogutu, Ben Andagalu, Hoseah M. Akala, Edwin Kamau
Publikováno v:
International Journal for Parasitology: Drugs and Drug Resistance, Vol 5, Iss 3, Pp 92-99 (2015)
Artemether–lumefantrine (AL) became the first-line treatment for uncomplicated malaria in Kenya in 2006. Studies have shown AL selects for SNPs in pfcrt and pfmdr1 genes in recurring parasites compared to the baseline infections. The genotypes asso
Externí odkaz:
https://doaj.org/article/abbbeff2eee247d5bab114bd5d409723
Autor:
Gladys C. Chemwor, Ben M. Andagalu, Irene A. Onyango, Benjamin H. Opot, Raphael O. Okoth, Redemptah A. Yedah, Jackline A. Juma, Edwin W. Mwakio, Wakoli M. Duncan, Joseph G. Amwoma, Agnes C. Cheruiyot, Dennis W. Juma, Timothy E. Egbo, Eric C. Garges, Amanda L. Roth, Edwin A. Kamau, Bernhards Ogutu, Oliver J. Watson, Hoseah Akala
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c3dbe13fb086f62de839dd0827bfd534
https://doi.org/10.2139/ssrn.4225657
https://doi.org/10.2139/ssrn.4225657
Autor:
Jennifer M. Mutisya, Victor A. Mobegi, Johnson K. Kinyua, Martha N. Kivecu, Raphael O. Okoth, Gladys C. Chemwor, Edwin W. Mwakio, Agnes C. Cheruiyot, Redempta A. Yeda, Charles O. Okello, Jackline A. Juma, Benjamin H. Opot, Dennis W. Juma, Amanda L. Roth, Hosea M. Akala, Ben M. Andagalu
Publikováno v:
F1000Research. 9:1268
Background: The emergence of artemisinin resistance in South East Asia calls for urgent discovery of new drug compounds that have antiplasmodial activity. Unlike the classical compound screening drug discovery methods, the rational approach involving
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e79c1143f21fb460e85aab5854756b8
https://doi.org/10.12688/f1000research.26756.2
https://doi.org/10.12688/f1000research.26756.2
Autor:
Jennifer M, Mutisya, Victor A, Mobegi, Johnson K, Kinyua, Martha N, Kivecu, Raphael O, Okoth, Gladys C, Chemwor, Edwin W, Mwakio, Agnes C, Cheruiyot, Redempta A, Yeda, Charles O, Okello, Jackline A, Juma, Benjamin H, Opot, Dennis W, Juma, Amanda L, Roth, Hosea M, Akala, Ben M, Andagalu
Publikováno v:
F1000Research. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d24ce5f44bb85121d9b5c3b2b5d0f0a4
https://pubmed.ncbi.nlm.nih.gov/35600144
https://pubmed.ncbi.nlm.nih.gov/35600144
Autor:
Jelagat, Cheruiyot, Luicer A, Ingasia, Angela A, Omondi, Dennis W, Juma, Benjamin H, Opot, Joseph M, Ndegwa, Joan, Mativo, Agnes C, Cheruiyot, Redemptah, Yeda, Charles, Okudo, Peninah, Muiruri, Ngalah S, Bidii, Lorna J, Chebon, Paul O, Angienda, Fredrick L, Eyase, Jacob D, Johnson, Wallace D, Bulimo, Ben, Andagalu, Hoseah M, Akala, Edwin, Kamau
Publikováno v:
Antimicrobial agents and chemotherapy. 58(7)
In combination with antibiotics, quinine is recommended as the second-line treatment for uncomplicated malaria, an alternative first-line treatment for severe malaria, and for treatment of malaria in the first trimester of pregnancy. Quinine has been
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::78684d8d9159e49cb5af5801ac49427d
https://pubmed.ncbi.nlm.nih.gov/24752268
https://pubmed.ncbi.nlm.nih.gov/24752268