Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Benjamin Guiastrennec"'
Autor:
Brian M. Maas, Jos Lommerse, Nele Plock, Radha A. Railkar, S.Y. Amy Cheung, Luzelena Caro, Jingxian Chen, Wen Liu, Ying Zhang, Qinlei Huang, Wei Gao, Li Qin, Jie Meng, Han Witjes, Emilie Schindler, Benjamin Guiastrennec, Francesco Bellanti, Daniel S. Spellman, Brad Roadcap, Mariya Kalinova, Juin Fok-Seang, Andrew P. Catchpole, Amy S. Espeseth, S. Aubrey Stoch, Eseng Lai, Kalpit A. Vora, Antonios O. Aliprantis, Jeffrey R. Sachs
Publikováno v:
EBioMedicine, Vol 73, Iss , Pp 103651- (2021)
Background: Neutralizing mAbs can prevent communicable viral diseases. MK-1654 is a respiratory syncytial virus (RSV) F glycoprotein neutralizing monoclonal antibody (mAb) under development to prevent RSV infection in infants. Development and validat
Externí odkaz:
https://doaj.org/article/29110f874edd46dea00e331b42ac8484
Autor:
Benjamin Guiastrennec, David P. Sonne, Martin Bergstrand, Tina Vilsbøll, Filip K. Knop, Mats O. Karlsson
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 7, Iss 9, Pp 603-612 (2018)
Bile acids released postprandially can modify the rate and extent of lipophilic compounds’ absorption. This study aimed to predict the enterohepatic circulation (EHC) of total bile acids (TBAs) in response to caloric intake from their spillover in
Externí odkaz:
https://doaj.org/article/64b1229fb37e4ce3bcf2476ace11cf46
Autor:
Hwa-Ping Feng, Vincent Duval, Matthew L. Rizk, Dan Li, Carisa De Anda, Margaret Z Chou, Philip Sabato, Aziz Ouerdani, Natalya Broyde, Benjamin Guiastrennec, Pamela Sears, Catherine Hardalo
Publikováno v:
Antimicrobial Agents and Chemotherapy
Tedizolid phosphate is an oxazolidinone antibacterial agent approved for the treatment of Gram-positive acute bacterial skin and skin structure infections (ABSSSIs) in patients aged ≥12 years. To support the use of tedizolid phosphate in adolescent
Autor:
Francesco Bellanti, Antonios O. Aliprantis, Juin Fok-Seang, Wen Liu, Jeffrey R. Sachs, Radha Railkar, Brad Roadcap, Kalpit A. Vora, Qinlei Huang, Li Qin, Nele Plock, W. Gao, Eseng Lai, Daniel S. Spellman, Jingxian Chen, Andrew P. Catchpole, Emilie Schindler, Mariya Kalinova, Amy S. Espeseth, Jie Meng, S. Y. Amy Cheung, Luzelena Caro, S. Aubrey Stoch, Benjamin Guiastrennec, Jos Lommerse, Brian M. Maas, Ying Zhang, Han Witjes
Publikováno v:
EBioMedicine, Vol 73, Iss, Pp 103651-(2021)
EBioMedicine
EBioMedicine
Background Neutralizing mAbs can prevent communicable viral diseases. MK-1654 is a respiratory syncytial virus (RSV) F glycoprotein neutralizing monoclonal antibody (mAb) under development to prevent RSV infection in infants. Development and validati
Autor:
Gustaf J. Wellhagen, Kim Brøsen, Mette Marie Hougaard Christensen, Benjamin Guiastrennec, Maria C. Kjellsson, Tore Bjerregaard Stage
Publikováno v:
Stage, T B, Wellhagen, G, Christensen, M M H, Guiastrennec, B, Brøsen, K & Kjellsson, M C 2019, ' Using a semi-mechanistic model to identify the main sources of variability of metformin pharmacokinetics ', Basic & Clinical Pharmacology & Toxicology, vol. 124, no. 1, pp. 105-114 . https://doi.org/10.1111/bcpt.13139
Metformin pharmacokinetics (PK) is highly variable, and researchers have for years tried to shed light on determinants of inter-individual (IIV) and inter-occasion variability (IOV) of metformin PK. We set out to identify the main sources of PK varia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e34b5c811e89bad20db91948e42c2337
https://findresearcher.sdu.dk:8443/ws/files/146453151/Using_a_semi_mechanistic_model_to_identify_the_main_sources_of_variability_of_metformin_pharmacokinetics.pdf
https://findresearcher.sdu.dk:8443/ws/files/146453151/Using_a_semi_mechanistic_model_to_identify_the_main_sources_of_variability_of_metformin_pharmacokinetics.pdf
Autor:
P. K. Bhavani, Mats O. Karlsson, Radojka M. Savic, Geetha Ramachandran, Soumya Swaminathan, Benjamin Guiastrennec, Amita Gupta, A K Hemanth Kumar, Kelly E. Dooley, N. Poorana Gangadevi
Publikováno v:
Clinical pharmacology and therapeutics, vol 104, iss 4
Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics
This work aimed to evaluate the once-daily antituberculosis treatment as recommended by the new Indian pediatric guidelines. Isoniazid, rifampin, and pyrazinamide concentration-time profiles and treatment outcome were obtained from 161 Indian childre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a0453dbff2b213dcbafdf76ad44974
https://escholarship.org/uc/item/76f394qq
https://escholarship.org/uc/item/76f394qq
Publikováno v:
Pharmaceutical Research
Purpose To develop a model linking in vitro and in vivo erosion of extended release tablets under fasting and postprandial status. Methods A nonlinear mixed-effects model was developed from the in vitro erosion profiles of four hydroxypropyl methylce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea4af8a45f933b59fb7663484c97d0cf
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-321446
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-321446
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology
ADAPT 5 is a powerful modeling software for population pharmacokinetic and pharmacodynamic systems analysis, but provides limited built-in functionality for creating pre- and post-analysis diagnostic plots. ADAPT 5 Model Evaluation Graphical Toolkit