Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Benjamin Georgi"'
Autor:
Spela Kokelj, Jörgen Östling, Benjamin Georgi, Karin Fromell, Kristina Nilsson Ekdahl, Henric K. Olsson, Anna-Carin Olin
Publikováno v:
Respiratory Research, Vol 22, Iss 1, Pp 1-17 (2021)
Abstract Introduction Cigarette smoke triggers many cellular and signaling responses in the lung and the resulting inflammation plays a central role in smoke-related lung diseases, such as COPD. We explored the effects of smoking on the small airway
Externí odkaz:
https://doaj.org/article/5bcca28bdf784098829aa5d98a4e8dc6
Autor:
Benjamin Georgi, David Craig, Rachel L Kember, Wencheng Liu, Ingrid Lindquist, Sara Nasser, Christopher Brown, Janice A Egeland, Steven M Paul, Maja Bućan
Publikováno v:
PLoS Genetics, Vol 10, Iss 3, p e1004229 (2014)
Bipolar disorder is a common, heritable mental illness characterized by recurrent episodes of mania and depression. Despite considerable effort to elucidate the genetic underpinnings of bipolar disorder, causative genetic risk factors remain elusive.
Externí odkaz:
https://doaj.org/article/1345e3e98470465ea318e2173d590b88
Publikováno v:
PLoS Genetics, Vol 9, Iss 5, p e1003484 (2013)
Understanding the core set of genes that are necessary for basic developmental functions is one of the central goals in biology. Studies in model organisms identified a significant fraction of essential genes through the analysis of null-mutations th
Externí odkaz:
https://doaj.org/article/58419f0b9fc74c90b04503a579f891e1
Autor:
Sebastian Haesler, Christelle Rochefort, Benjamin Georgi, Pawel Licznerski, Pavel Osten, Constance Scharff
Publikováno v:
PLoS Biology, Vol 5, Iss 12, p e321 (2007)
The gene encoding the forkhead box transcription factor, FOXP2, is essential for developing the full articulatory power of human language. Mutations of FOXP2 cause developmental verbal dyspraxia (DVD), a speech and language disorder that compromises
Externí odkaz:
https://doaj.org/article/b9060776d29b4da9845373e02fd69674
Autor:
Kristina Nilsson Ekdahl, Jörgen Östling, Spela Kokelj, Karin Fromell, Benjamin Georgi, Henric Olsson, Anna-Carin Olin
Publikováno v:
Respiratory Research
Respiratory Research, Vol 22, Iss 1, Pp 1-17 (2021)
Respiratory Research, Vol 22, Iss 1, Pp 1-17 (2021)
Introduction Cigarette smoke triggers many cellular and signaling responses in the lung and the resulting inflammation plays a central role in smoke-related lung diseases, such as COPD. We explored the effects of smoking on the small airway proteome
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f45ec0ea3d93ca2444d67268bd8e07d
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-452710
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-452710
Late Breaking Abstract - Proteomic changes in respiratory tract lining fluid associated with smoking
Publikováno v:
Molecular pathology and funct. genomics.
Smoking is the main risk factor for chronic obstructive pulmonary disease (COPD). The aim of this study was to identify dysregulation of specific proteins and pathways associated with smoking in samples from small airways obtained non-invasively with
Autor:
Maja Bucan, Dwight Stambolian, Joan E. Bailey-Wilson, Benjamin Georgi, Rachel L. Kember, Steven M. Paul
Publikováno v:
BMC Genetics
Background Bipolar affective disorder (BP) is a common, highly heritable psychiatric disorder characterized by periods of depression and mania. Using dense SNP genotype data, we characterized CNVs in 388 members of an Old Order Amish Pedigree with bi
Autor:
Benjamin Georgi, Alexander Schliep
Publikováno v:
ISMB (Supplement of Bioinformatics)
Motivation: A positional weight matrix (PWM) is a statistical representation of the binding pattern of a transcription factor estimated from known binding site sequences. Previous studies showed that for factors which bind to divergent binding sites,
Autor:
Benjamin Georgi, Erik G. Puffenberger, Wencheng Liu, Yutao Tian, Sander Markx, Steven M. Paul, Aravinda Chakravarti, Michael B. First, Toshinori Hoshi, Kevin A. Strauss, Maja Bucan, Robert N. Jinks, Abigail R. Benkert, Ann McDonald, Adam D. Heaps
Publikováno v:
Human Molecular Genetics
We conducted blinded psychiatric assessments of 26 Amish subjects (52 ± 11 years) from four families with prevalent bipolar spectrum disorder, identified 10 potentially pathogenic alleles by exome sequencing, tested association of these alleles with
Publikováno v:
Knowledge Discovery in Databases: PKDD 2007 ISBN: 9783540749752
PKDD
PKDD
Protein families can be divided into subgroups with functional differences. The analysis of these subgroups and the determination of which residues convey substrate specificity is a central question in the study of these families. We present a cluste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::947d5cb906194b3446e3e281163645e3
https://doi.org/10.1007/978-3-540-74976-9_11
https://doi.org/10.1007/978-3-540-74976-9_11