Nanofocused Scanning X-ray Fluorescence Microscopy Revealing an Effect of Heterozygous Hemoglobin S and C on Biochemical Activities in Plasmodium falciparum-Infected Erythrocytes

Autor: Christine Lansche, Cecilia P. Sanchez, Benjamin Fröhlich, Peter Cloetens, Judith Thoma, Yang Yang, Julian Czajor, Michael Lanzer, Motomu Tanaka

Publikováno v: Analytical Chemistry. 92:5765-5771

While there is ample evidence suggesting that carriers of heterozygous hemoglobin S and C are protected from life-threatening malaria, little is known about the underlying biochemical mechanisms at the single cell level. Using nanofocused scanning X-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::b167d016153cc17a4e933dc2f49812b0
https://doi.org/10.1021/acs.analchem.9b05111

Uncertainty quantification of large-scale dynamical systems using parametric model order reduction

Autor: Benjamin Fröhlich, Dominik Hose, Oliver Dieterich, Michael Hanss, Peter Eberhard

Publikováno v: Mechanical Systems and Signal Processing. 171:108855

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::65f338c9cc099ffa31c756bdcabab611
https://doi.org/10.1016/j.ymssp.2022.108855

The sickle cell trait affects contact dynamics and endothelial cell activation in Plasmodium falciparum-infected erythrocytes

Autor: Dimitris Missirlis, Christine Lansche, Marilou Tétard, Anil K. Dasanna, Benjamin Fröhlich, Benoit Gamain, Ulrich S. Schwarz, Cecilia P. Sanchez, Katharina A. Quadt, Bernd Buchholz, Motomu Tanaka, Michael Lanzer

Publikováno v: Communications Biology, Vol 1, Iss 1, Pp 1-14 (2018)
Communications Biology
Communications Biology, Nature Publishing Group, 2018, 1 (1), ⟨10.1038/s42003-018-0223-3⟩

Sickle cell trait, a common hereditary blood disorder, protects carriers from severe disease in infections with the human malaria parasite Plasmodium falciparum. Protection is associated with a reduced capacity of parasitized erythrocytes to cytoadhe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ae7fdc3d5b32dd1b138b7b292d2de34
http://link.springer.com/article/10.1038/s42003-018-0223-3

Geometric element parameterization and parametric model order reduction in finite element based shape optimization

Autor: Peter Eberhard, Jan Gade, Florian Geiger, Benjamin Fröhlich, Manfred Bischoff

Publikováno v: Computational Mechanics. 63:853-868

This contribution proposes a new approach to derive geometrically parameterized, reduced order finite element models. An element formulation for geometrically parameterized finite elements is suggested. The parameterized elements are used to derive m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90e9975d6a37bd28c9008777d29a66d6
https://doi.org/10.1007/s00466-018-1626-1

Model Order Reduction of Coupled, Parameterized Elastic Bodies for Shape Optimization

Autor: Jan Gade, Benjamin Fröhlich, Florian Geiger, Manfred Bischoff, Peter Eberhard

Publikováno v: IUTAM Symposium on Model Order Reduction of Coupled Systems, Stuttgart, Germany, May 22–25, 2018 ISBN: 9783030210120

In this contribution, coupled, parameterized second order systems are considered where the coupled, parameterized system is derived from the assembly of several parameterized component models. Two approaches for the Parametric Model Order Reduction o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::388b06342c02697ca281155a0b38ea6e
https://doi.org/10.1007/978-3-030-21013-7_11