Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Benjamin F Brinkmann"'
Autor:
Jonas Franz, Benjamin F Brinkmann, Michael König, Jana Hüve, Christian Stock, Klaus Ebnet, Christoph Riethmüller
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146598 (2016)
Endothelial barriers have a central role in inflammation as they allow or deny the passage of leukocytes from the vasculature into the tissue. To bind leukocytes, endothelial cells form adhesive clusters containing tetraspanins and ICAM-1, so-called
Externí odkaz:
https://doaj.org/article/32439498e7e7483c91682c335348a9da
Autor:
Alexander Schwickert, Esther Weghake, Kathrin Brüggemann, Annika Engbers, Benjamin F Brinkmann, Björn Kemper, Jochen Seggewiß, Christian Stock, Klaus Ebnet, Ludwig Kiesel, Christoph Riethmüller, Martin Götte
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0143993 (2015)
MicroRNAs (miRNAs, micro ribonucleic acids) are pivotal post-transcriptional regulators of gene expression. These endogenous small non-coding RNAs play significant roles in tumorigenesis and tumor progression. miR-142-3p expression is dysregulated in
Externí odkaz:
https://doaj.org/article/80b110fb41814150b0849a143158fdcf
Autor:
Gonzalo Rosso, Nicole Heitzig, Victor Shahin, Ursula Rescher, Sophia N. Koerdt, Benjamin F. Brinkmann
Publikováno v:
Cell Adhesion & Migration. 11:275-287
The physiological and pathological process of angiogenesis relies on orchestrated endothelial cell (EC) adhesion, migration and formation of new vessels. Here we report that human umbilical vein endothelial cells (HUVECs) deficient in Annexin A8 (Anx
Autor:
Thomas Weide, Tim Steinbacher, Klaus Ebnet, Denise Pajonczyk, Volker Gerke, Fatemeh Mirzapourshafiyi, Benjamin F. Brinkmann, Daniel Kummer, Christian Hartmann, Masanori Nakayama
Publikováno v:
Molecular Biology of the Cell
Blood vessel tubulogenesis requires the establishment of apicobasal polarity of endothelial cells. A novel interaction is described of the cell adhesion molecule VE-cadherin with the cell polarity protein Pals1. The activity of VE-cadherin in regulat
Publikováno v:
Cell Polarity 1 ISBN: 9783319144627
Epithelial and endothelial cells are embedded in sheets of cells and have a pronounced apicobasal polarity. The development of apicobasal polarity is regulated by a conserved set of cell polarity proteins which regulate different aspects of cellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aedf2cff090a2be8569439f0c9d206a
https://doi.org/10.1007/978-3-319-14463-4_12
https://doi.org/10.1007/978-3-319-14463-4_12
Publikováno v:
Cell Cycle. 14:3773-3774
Epithelial cells form sheets of cells which are connected by intercellular junctions. When epithelial cells divide the mitotic spindle is aligned in the plane of the sheet, which ensures that both daughter cells are retained in the sheet. The planar
Autor:
Daniel Kummer, Hüseyin Tuncay, Masanori Nakayama, Swetha Peddibhotla, Ralf H. Adams, Volker Gerke, Benjamin F. Brinkmann, Klaus Ebnet
Publikováno v:
Molecular Biology of the Cell
This paper describes a ternary protein complex consisting of junctional adhesion molecule-A (JAM-A), tetraspanin CD9, and αvβ3 integrin in endothelial cells. In this complex, CD9 links JAM-A to αvβ3 integrin to regulate basic fibroblast growth fa
Autor:
Daniel Kummer, Steve Misselwitz, Klaus Ebnet, Swetha Peddibhotla, Hüseyin Tuncay, Benjamin F. Brinkmann
Publikováno v:
Cancer Metastasis-Biology and Treatment ISBN: 9789400760271
Tight junctions form a barrier for solutes at cell-cell contacts of epithelial and endothelial cells. Within the vasculature, they are particularly well developed between endothelial cells of the blood brain barrier to protect the brain from potentia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1950507f3d699fdfb187fb554433963a
https://doi.org/10.1007/978-94-007-6028-8_5
https://doi.org/10.1007/978-94-007-6028-8_5
Autor:
Lamia A Bahnassawy, Sandra Stelzer, Eva C. Bunk, Kathrin Hemmer, Jens Christian Schwamborn, Kirite Rugani, Benjamin F. Brinkmann, Anna-Lena Schon, Maik M. A. Worlitzer, Klaus Ebnet, Thomas Palm, Inga Werthschulte
Publikováno v:
Stem cells and development. 21(5)
Junctional adhesion molecule-C (JAM-C) is an adhesive cell surface protein expressed in various cell types. JAM-C localizes to the apically localized tight junctions (TJs) between contacting endothelial and epithelial cells, where it contributes to c
Publikováno v:
Biology of the cell. 103(8)
Background information. ROS (reactive oxygen species) as well as components of the antioxidant redox systems may act as signals. To link acute environmental change with gene expression, changes in ROS and GSH/GSSG (reduced/oxidized glutathione) level