Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Benjamin Ellingson"'
Autor:
Meral A. Tubi, Evan Lutkenhoff, Manuel Buitrago Blanco, David McArthur, Pablo Villablanca, Benjamin Ellingson, Ramon Diaz-Arrastia, Paul Van Ness, Courtney Real, Vikesh Shrestha, Jerome Engel, Jr., Paul M. Vespa
Publikováno v:
Neurobiology of Disease, Vol 123, Iss , Pp 115-121 (2019)
Objective: Injury severity after traumatic brain injury (TBI) is a well-established risk factor for the development of post-traumatic epilepsy (PTE). However, whether lesion location influences the susceptibility of seizures and development of PTE lo
Externí odkaz:
https://doaj.org/article/b806683e22ca4726ab314fcbf945dbe7
Autor:
Eva-Maria Ratai, Zheng Zhang, James Fink, Mark Muzi, Lucy Hanna, Erin Greco, Todd Richards, Daniel Kim, Ovidiu C Andronesi, Akiva Mintz, Lale Kostakoglu, Melissa Prah, Benjamin Ellingson, Kathleen Schmainda, Gregory Sorensen, Daniel Barboriak, David Mankoff, Elizabeth R Gerstner, ACRIN 6684 trial group
Publikováno v:
PLoS ONE, Vol 13, Iss 6, p e0198548 (2018)
A multi-center imaging trial by the American College of Radiology Imaging Network (ACRIN) "A Multicenter, phase II assessment of tumor hypoxia in glioblastoma using 18F Fluoromisonidazole (FMISO) with PET and MRI (ACRIN 6684)", was conducted to asses
Externí odkaz:
https://doaj.org/article/82531403d7ea48b78564101715f30dcd
Autor:
Saman Hazany, Kim-Lien Nguyen, Martin Lee, Andrew Zhang, Parsa Mokhtar, Alexander Crossley, Sakshi Luthra, Pooja Butani, Sunita Dergalust, Benjamin Ellingson, Jason D. Hinman
Publikováno v:
Journal of Clinical Neuroscience. 105:131-136
Current methods for quantitative assessment of cerebral small vessel disease (CSVD) ignore critical aspects of the disease, namely lesion type and regionality. We developed and tested a new scoring system for CSVD, "regional Cerebral Small Vessel Dis
Autor:
Ingo K. Mellinghoff, Brian Alexander, Donald Berry, Nicholas Blondin, Meredith Buxton, Webster Cavenee, Howard Colman, John de Groot, Macarena I. de la Fuente, Benjamin Ellingson, Gary Gordon, Emma M.V. Hyddmark, Mustafa Khasraw, Andrew Lassman, Eudocia Lee, Wenbin Li, Michael Lim, Tom Mikkelsen, Apoorva Nelli, James Perry, Erik Sulman, Kirk Tanner, Michael Weller, Patrick Y. Wen, Timothy Cloughesy
Publikováno v:
Cancer Research. 83:CT062-CT062
Background: GBM AGILE (Glioblastoma Adaptive, Global, Innovative Learning Environment) is a biomarker based, multi-arm, international, seamless Phase 2/3 Response Adaptive Randomization platform trial designed to rapidly identify experimental therapi
Autor:
Nicholas S Cho, Shruti Thakuria, Francesco Sanvito, Akifumi Hagiwara, Chencai Wang, Raksha Nagaraj, Jianwen Lu, Sonoko Oshima, Catalina Raymond, Timothy Cloughesy, Linda M Liau, Richard G Everson, Phioanh L Nghiemphu, Albert Lai, Benjamin Ellingson
Publikováno v:
Neuro-Oncology. 24:vii174-vii175
INTRODUCTION Sodium MRI has been recently explored in brain tumors to potentially reveal complementary information with proton MRI about the tumor microenvironment. However, there remains limited investigation combining sodium and quantitative proton
Autor:
Benjamin Ellingson, Patrick Y Wen, Susan Chang, Martin van den Bent, Michael Vogelbaum, Gang Li, Shanpeng Li, Jiyoon Kim, Gilbert Youssef, Wolfgang Wick, Andrew Lassman, Mark Gilbert, John de Groot, Michael Weller, Evanthia Galanis, Timothy Cloughesy
Publikováno v:
Neuro-Oncology. 24:vii172-vii173
Durable overall response rate (ORR) remains a meaningful endpoint in recurrent GBM; however, the target ORR for single arm recurrent GBM trials has not been based on historic information or tied to patient outcomes. The current study reviewed past tr
Autor:
Benjamin Ellingson, David Nathanson, Jingwen Yao, Akifumi Hagiwara, Catalina Raymond, Noriko Salamon, Whitney Pope, Albert Lai, Phioanh L Nghiemphu, Timothy Cloughesy
Publikováno v:
Neuro-Oncology. 24:vii170-vii171
In recently published work, we demonstrated that acute inhibition of the EGFR – the most frequently altered oncogene in GBM – can rapidly reduce glycolysis in a subset of GBM. To quantify this effect, we propose a new combination metabolic MR-PET
Autor:
Patrick Y Wen, John de Groot, James Battiste, Samuel Goldlust, Denise Damek, Benjamin Ellingson, James Garner, John Friend, Jeremy Simpson, Alan Olivero, Timothy Cloughesy
Publikováno v:
Neuro-Oncology. 24:vii76-vii77
NCT03522298 was an open-label, multi-center, 2-stage trial designed to establish the maximum tolerated dose (MTD) for once-daily (QD) paxalisib dosing (Stage 1), then evaluate pharmacokinetics(PK) and safety and explore efficacy (Stage 2). Eligible p
Autor:
Shivani Baisiwala, Lu Sun, Benjamin Ellingson, Robert Prins, Phioanh L Nghiemphu, Timothy Cloughesy, Richard G Everson
Publikováno v:
Neuro-Oncology. 24:vii61-vii62
Neoadjuvant drug administration provides a window of opportunity for developing novel therapies. Specifically, neoadjuvant pembrolizumab (PD1 checkpoint inhibitor) has the potential for improving understanding of immunomodulatory effects on the tumor