Zobrazeno 1 - 10
of 144
pro vyhledávání: '"Benjamin E. Blass"'
Autor:
Mark D. Namba, Megan N. Phillips, Peng-Jen Chen, Benjamin E. Blass, M. Foster Olive, Janet L. Neisewander
Publikováno v:
Addiction Neuroscience, Vol 5, Iss , Pp 100062- (2023)
Cocaine Use Disorders (CUDs) are associated with an increased risk of human immunodeficiency virus (HIV) infection. Cocaine and the HIV envelope protein gp120 each induce distinct deficits to mesocorticolimbic circuit function and motivated behavior;
Externí odkaz:
https://doaj.org/article/68d33bc6c608440aaf889bc0e99ffd59
Autor:
Samantha N. Scott, Brielle A. Ruscitti, Raul Garcia, Toan T. Nguyen, Kevin M. Blattner, Benjamin E. Blass, Janet L. Neisewander
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Background: Previous research showed that the 5-HT1B receptor agonist CP94253 enhanced cocaine reinforcement rate during maintenance of daily self-administration (SA), but inhibited reinforcement rate after 21 days of abstinence in male rats. Here we
Externí odkaz:
https://doaj.org/article/7ca8aa0c22ac447d84592675391d04dc
Publikováno v:
Molecular Neurodegeneration, Vol 15, Iss 1, Pp 1-11 (2020)
Abstract Background The vacuolar protein sorting 35 (VPS35) is a major component of the retromer complex system, an ubiquitous multiprotein assembly responsible for sorting and trafficking protein cargos out of the endosomes. VPS35 can regulate APP m
Externí odkaz:
https://doaj.org/article/3bd2ff0d998342d19730ea8e87c87f91
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 8, Iss 1, Pp n/a-n/a (2022)
Abstract Introduction Retromer complex proteins are decreased in Down syndrome (DS) brains and correlate inversely with brain amyloidosis. However, whether retromer dysfunction contributes to the amyloid beta (Aβ) and tau neuropathology of DS remain
Externí odkaz:
https://doaj.org/article/762a171bcdf54b88a842a1156a594ce7
Publikováno v:
Molecular Neurodegeneration, Vol 16, Iss 1, Pp 1-2 (2021)
Externí odkaz:
https://doaj.org/article/0885133593dd45429fe0ee1d3c01dcf3
The Long-Acting D3 Partial Agonist MC-25-41 Attenuates Motivation for Cocaine in Sprague-Dawley Rats
Autor:
Gregory L. Powell, Mark D. Namba, Annika Vannan, John Paul Bonadonna, Andrew Carlson, Rachel Mendoza, Peng-Jen Chen, Robert R. Luetdke, Benjamin E. Blass, Janet L. Neisewander
Publikováno v:
Biomolecules, Vol 10, Iss 7, p 1076 (2020)
The dopamine D3 receptor is a prime target for developing treatments for cocaine use disorders (CUDs). In this study, we conducted a pre-clinical investigation of the therapeutic potential of a long-acting, D3 receptor partial agonist, MC-25-41. Male
Externí odkaz:
https://doaj.org/article/0b79670df5dc40418c5b24ac1cf43868
Publikováno v:
Journal of Alzheimer's Disease. 91:463-469
Background: The endosomal retromer complex system is a key controller for trafficking of proteins. Downregulation of its recognition core proteins, such as VPS35, is present in Alzheimer’s disease (AD) brain, whereas its normalization prevents the
Autor:
Xiaoying Jiang, Kaiyu Wu, Xiang‐Yang Ye, Tian Xie, Pengfei Zhang, Benjamin E. Blass, Renren Bai
Publikováno v:
Medicinal Research Reviews.
Autor:
Benjamin E. Blass, Kevin M. Blattner, John C. Gordon, Khaled M. Elokely, Douglas A. Pippin, Daniel J. Canney
Publikováno v:
Medicinal Chemistry Research. 31:1209-1223
Publikováno v:
Medicinal Chemistry Research. 31:735-748