Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Benjamin E Reubinoff"'
Publikováno v:
PLoS Genetics, Vol 17, Iss 3, p e1009445 (2021)
Expansion of the hexanucleotide repeat (HR) in the first intron of the C9orf72 gene is the most common genetic cause of amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) in Caucasians. All C9orf72-ALS/FTD patients share a common r
Externí odkaz:
https://doaj.org/article/be2976136eec4a4eb294ed7d3cbeb49a
Autor:
Shelly E Tannenbaum, Orna Singer, Yaniv Gil, Yael Berman-Zaken, Nili Ilouz, Hanita Khaner, Miriam Haimov, Benjamin E Reubinoff
Publikováno v:
Stem Cell Research, Vol 42, Iss , Pp - (2020)
The Hadassah hESC Research Center's aim is to be a supplier of clinical and research-grade human embryonic stem cell (hESC) lines. In 2012, we derived the first three entirely GMP-compliant and xeno-free, fully-characterised, feeder-dependent (human
Externí odkaz:
https://doaj.org/article/7184e255345d42c3a30d1fed56a27759
Autor:
Shelly E Tannenbaum, Tikva Tako Turetsky, Orna Singer, Einat Aizenman, Sophie Kirshberg, Nili Ilouz, Yaniv Gil, Yael Berman-Zaken, Temima Schnitzer Perlman, Nitshia Geva, Ora Levy, Daniel Arbell, Alex Simon, Assaf Ben-Meir, Yoel Shufaro, Neri Laufer, Benjamin E Reubinoff
Publikováno v:
PLoS ONE, Vol 7, Iss 6, p e35325 (2012)
Clinically compliant human embryonic stem cells (hESCs) should be developed in adherence to ethical standards, without risk of contamination by adventitious agents. Here we developed for the first time animal-component free and good manufacturing pra
Externí odkaz:
https://doaj.org/article/d8c1b5618fee468584f5e8577cfa9b2b
Autor:
Michal Gropp, Vitali Shilo, Gilad Vainer, Miri Gov, Yaniv Gil, Hanita Khaner, Limor Matzrafi, Maria Idelson, Juri Kopolovic, Naomi B Zak, Benjamin E Reubinoff
Publikováno v:
PLoS ONE, Vol 7, Iss 9, p e45532 (2012)
Teratoma tumor formation is an essential criterion in determining the pluripotency of human pluripotent stem cells. However, currently there is no consistent protocol for assessment of teratoma forming ability. Here we present detailed characterizati
Externí odkaz:
https://doaj.org/article/eb264c649af849c4bb4e1a1763cc385c
Autor:
Galit Tzur, Ariel Israel, Asaf Levy, Hila Benjamin, Eti Meiri, Yoel Shufaro, Karen Meir, Elina Khvalevsky, Yael Spector, Nathan Rojansky, Zvi Bentwich, Benjamin E Reubinoff, Eithan Galun
Publikováno v:
PLoS ONE, Vol 4, Iss 10, p e7511 (2009)
BACKGROUND AND AIMS: microRNAs (miRNAs) are small noncoding RNAs that regulate cognate mRNAs post-transcriptionally. miRNAs have been implicated in regulating gene expression in embryonic developmental processes, including proliferation and different
Externí odkaz:
https://doaj.org/article/88cefa5909ca4e21aa39f564124e3bda
Autor:
Galit Tzur, Asaf Levy, Eti Meiri, Omer Barad, Yael Spector, Zvi Bentwich, Lina Mizrahi, Mark Katzenellenbogen, Etti Ben-Shushan, Benjamin E Reubinoff, Eithan Galun
Publikováno v:
PLoS ONE, Vol 3, Iss 11, p e3726 (2008)
BACKGROUND/AIMS: microRNAs (miRNAs) are small noncoding RNAs that regulate cognate mRNAs post-transcriptionally. Human embryonic stem cells (hESC), which exhibit the characteristics of pluripotency and self-renewal, may serve as a model to study the
Externí odkaz:
https://doaj.org/article/1e94d3ecf2f349b4b8cc9b7202a9de76
Autor:
Michal, Gropp, Ithai, Waldhorn, Yaniv, Gil, Debora, Steiner, Tikva Tako, Turetsky, Yoav, Smith, Ofra, Sabag, Tal, Falick-Michaeli, Sharona Even, Ram, Benjamin E, Reubinoff
Publikováno v:
Stem Cell Reports. 17:2643-2660
In the mammalian embryo, a formative pluripotent phase is proposed to exist at the early post-implantation period, during the transition from the pre-implantation naive-to the post-implantation primed-epiblast. By recapitulating a laminin component o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::154b9d60bb5d1842ede1d16c0bf250fb
https://doi.org/10.1016/j.stemcr.2022.10.010
https://doi.org/10.1016/j.stemcr.2022.10.010
Autor:
Emanuel Segal, Jonathan Nissenbaum, Mordecai Peretz, Tamar Golan‐Lev, Rivki Cashman, Hagit Philip, Benjamin E. Reubinoff, Oded Kopper, Nissim Benvenisty
Publikováno v:
Cell Proliferation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e96affe13b5c311c5ad3d2e4f0109738
https://doi.org/10.1111/cpr.13475
https://doi.org/10.1111/cpr.13475
Publikováno v:
Cell Proliferation. 55
For use in regenerative medicine, large-scale manufacturing of human pluripotent stem cells (hPSCs) under current good manufacturing practice (cGMPs) is required. Much progress has been made since culturing under static two-dimensional (2D) condition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2029ae046ebd9e2546e8ac80580cda5f
https://doi.org/10.1111/cpr.13247
https://doi.org/10.1111/cpr.13247
Autor:
Ithai Waldhorn, Tikva Turetsky, Debora Steiner, Yaniv Gil, Hadar Benyamini, Michal Gropp, Benjamin E. Reubinoff
Publikováno v:
Stem cell reports. 17(12)
Biological sex is a fundamental trait influencing development, reproduction, pathogenesis, and medical treatment outcomes. Modeling sex differences is challenging because of the masking effect of genetic variability and the hurdle of differentiating
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17a2aac331de78c348fc28a691ec5383
https://pubmed.ncbi.nlm.nih.gov/36427492
https://pubmed.ncbi.nlm.nih.gov/36427492