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Fibrin(ogen) Promotes Immune Cell Infiltration, Dysbiosis and ROS Production in Experimental Colitis
Autor:
Matthew J. Flick, Lindsey E. Romick-Rosendale, Benjamin E Gourley, Leah Rosenfeldt, Olivia Edwards, Miki Watanabe, Ramesh Kudira, David B. Haslam, Joseph S. Palumbo, Bal Krishan Sharma, Rachel Cantrell
Publikováno v:
Blood. 138:443-443
Elevated stool fibrinogen has recently been shown to predict disease course in ulcerative colitis (UC), suggesting that fibrin(ogen) in the colitis microenvironment promotes UC pathogenesis. This conclusion is consistent with previous studies from ou