Zobrazeno 1 - 10
of 113
pro vyhledávání: '"Benjamin E Gewurz"'
Publikováno v:
PLoS Pathogens, Vol 20, Iss 4, p e1011939 (2024)
Epstein-Barr virus (EBV) persistently infects 95% of adults worldwide and is associated with multiple human lymphomas that express characteristic EBV latency programs used by the virus to navigate the B-cell compartment. Upon primary infection, the E
Externí odkaz:
https://doaj.org/article/26731686f3c145fda023abbea69b282f
Autor:
Eric M Burton, Benjamin E Gewurz
Publikováno v:
PLoS Pathogens, Vol 18, Iss 10, p e1010920 (2022)
[This corrects the article DOI: 10.1371/journal.ppat.1010254.].
Externí odkaz:
https://doaj.org/article/abce49e7a57c493c88362e5a84e1e6a1
Autor:
Lisa Beatrice Caruso, Rui Guo, Kelsey Keith, Jozef Madzo, Davide Maestri, Sarah Boyle, Jason Wasserman, Andrew Kossenkov, Benjamin E Gewurz, Italo Tempera
Publikováno v:
PLoS Pathogens, Vol 18, Iss 4, p e1010400 (2022)
The Epstein Barr virus (EBV) infects almost 95% of the population worldwide. While typically asymptomatic, EBV latent infection is associated with several malignancies of epithelial and lymphoid origin in immunocompromised individuals. In latently in
Externí odkaz:
https://doaj.org/article/871c0c5c914d4e37b3c934b3ff5cf0ad
Autor:
Eric M Burton, Benjamin E Gewurz
Publikováno v:
PLoS Pathogens, Vol 18, Iss 2, p e1010254 (2022)
Externí odkaz:
https://doaj.org/article/89df13ca65a2423d80cd86828434f6df
Autor:
Liang Wei Wang, Zhonghao Wang, Ina Ersing, Luis Nobre, Rui Guo, Sizun Jiang, Stephen Trudeau, Bo Zhao, Michael P Weekes, Benjamin E Gewurz
Publikováno v:
PLoS Pathogens, Vol 15, Iss 9, p e1008030 (2019)
Epstein-Barr virus (EBV) causes infectious mononucleosis and is associated with multiple human malignancies. EBV drives B-cell proliferation, which contributes to the pathogenesis of multiple lymphomas. Yet, knowledge of how EBV subverts host biosynt
Externí odkaz:
https://doaj.org/article/626d3ddf7a0d47f4a3a9b490786615c1
Autor:
Hannah Greenfeld, Kaoru Takasaki, Michael J Walsh, Ina Ersing, Katharina Bernhardt, Yijie Ma, Bishi Fu, Camille W Ashbaugh, Jackson Cabo, Sarah B Mollo, Hufeng Zhou, Shitao Li, Benjamin E Gewurz
Publikováno v:
PLoS Pathogens, Vol 11, Iss 5, p e1004890 (2015)
The Epstein-Barr virus (EBV) encoded oncoprotein Latent Membrane Protein 1 (LMP1) signals through two C-terminal tail domains to drive cell growth, survival and transformation. The LMP1 membrane-proximal TES1/CTAR1 domain recruits TRAFs to activate M
Externí odkaz:
https://doaj.org/article/0d72b21c044a46659a801c8faf642a7b
Regulation of p53 and Rb links the alternative NF-κB pathway to EZH2 expression and cell senescence.
Autor:
Alessio Iannetti, Adeline C Ledoux, Susan J Tudhope, Hélène Sellier, Bo Zhao, Sophia Mowla, Adam Moore, Holger Hummerich, Benjamin E Gewurz, Simon J Cockell, Parmjit S Jat, Elaine Willmore, Neil D Perkins
Publikováno v:
PLoS Genetics, Vol 10, Iss 9, p e1004642 (2014)
There are two major pathways leading to induction of NF-κB subunits. The classical (or canonical) pathway typically leads to the induction of RelA or c-Rel containing complexes, and involves the degradation of IκBα in a manner dependent on IκB ki
Externí odkaz:
https://doaj.org/article/aaddeaccf33b4b40bce0cfbdad0a4454
Autor:
Ina Ersing, Luis Nobre, Liang Wei Wang, Lior Soday, Yijie Ma, Joao A. Paulo, Yohei Narita, Camille W. Ashbaugh, Chang Jiang, Nicholas E. Grayson, Elliott Kieff, Steven P. Gygi, Michael P. Weekes, Benjamin E. Gewurz
Publikováno v:
Cell Reports, Vol 19, Iss 7, Pp 1479-1493 (2017)
Epstein-Barr virus (EBV) replication contributes to multiple human diseases, including infectious mononucleosis, nasopharyngeal carcinoma, B cell lymphomas, and oral hairy leukoplakia. We performed systematic quantitative analyses of temporal changes
Externí odkaz:
https://doaj.org/article/6d63a6d1609541e78227973b624273aa
Autor:
Chang Jiang, Stephen J. Trudeau, Taek-Chin Cheong, Rui Guo, Mingxiang Teng, Liang Wei Wang, Zhonghao Wang, Chiara Pighi, Carole Gautier-Courteille, Yijie Ma, Sizun Jiang, Chong Wang, Bo Zhao, Luc Paillard, John G. Doench, Roberto Chiarle, Benjamin E. Gewurz
Publikováno v:
Cell Reports, Vol 28, Iss 5, Pp 1307-1322.e8 (2019)
Summary: CD40 has major roles in B cell development, activation, and germinal center responses. CD40 hypoactivity causes immunodeficiency whereas its overexpression causes autoimmunity and lymphomagenesis. To systematically identify B cell autonomous
Externí odkaz:
https://doaj.org/article/b74d5505048f47989a48f9086351ba64
The Epstein-Barr virus oncogene latent membrane protein 1 (LMP1) is expressed by multiple EBV-associated malignancies, where it mimics CD40 signaling to activate growth and survival pathways. Two LMP1 cytoplasmic tail domains are essential for EBV-dr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30517f71899f849e76901400e1608b7f
https://doi.org/10.1101/2023.04.10.536234
https://doi.org/10.1101/2023.04.10.536234
