Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Benjamin E, Steinberg"'
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
HMGB1 is an inflammatory mediator released by a variety of cell types. Here, the authors show that unlike IL-1β, HMGB1 is released non-specifically following cell lysis.
Externí odkaz:
https://doaj.org/article/c6a06ee41e8d41538331a89542219cb7
Publikováno v:
Frontiers in Medicine, Vol 8 (2022)
Inflammasomes are multi-protein complexes that sense both infectious and sterile inflammatory stimuli, launching a cascade of responses to propagate danger signaling throughout an affected tissue. Recent studies have implicated inflammasome activatio
Externí odkaz:
https://doaj.org/article/d5803c0635b54f71a2481960516c7a65
Autor:
Jazlyn P. Borges, Katrina Mekhail, Gregory D. Fairn, Costin N. Antonescu, Benjamin E. Steinberg
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Chronic pain has been widely recognized as a major public health problem that impacts multiple aspects of patient quality of life. Unfortunately, chronic pain is often resistant to conventional analgesics, which are further limited by their various s
Externí odkaz:
https://doaj.org/article/30cb61b8aa824cab8b21e0995f05f8e9
Autor:
Nan Gai, Kazuyoshi Aoyama, David Faraoni, Neil M Goldenberg, David N Levin, Jason T Maynes, Mark J McVey, Farrukh Munshey, Asad Siddiqui, Timothy Switzer, Benjamin E Steinberg
Publikováno v:
PLoS ONE, Vol 16, Iss 2, p e0246427 (2021)
BackgroundThe COVID-19 pandemic has yielded an unprecedented quantity of new publications, contributing to an overwhelming quantity of information and leading to the rapid dissemination of less stringently validated information. Yet, a formal analysi
Externí odkaz:
https://doaj.org/article/c17b8df961c04714afab76ec2f822c4c
Autor:
Harold A. Silverman, Andrew Stiegler, Téa Tsaava, Justin Newman, Benjamin E. Steinberg, Emily Battinelli Masi, Sergio Robbiati, Chad Bouton, Patricio T. Huerta, Sangeeta S. Chavan, Kevin J. Tracey
Publikováno v:
Bioelectronic Medicine, Vol 4, Iss 1, Pp 1-13 (2018)
Abstract Background The vagus nerve plays an important role in the regulation of organ function, including reflex pathways that regulate immunity and inflammation. Recent studies using genetically modified mice have improved our understanding of mole
Externí odkaz:
https://doaj.org/article/eff1c9bddb264f14aa5d096d268bfa09
Autor:
Dean A Fergusson, Marc T Avey, Carly C Barron, Mathew Bocock, Kristen E Biefer, Sylvain Boet, Stephane L Bourque, Isidora Conic, Kai Chen, Yuan Yi Dong, Grace M Fox, Ronald B George, Neil M Goldenberg, Ferrante S Gragasin, Prathiba Harsha, Patrick J Hong, Tyler E James, Sarah M Larrigan, Jenna L MacNeil, Courtney A Manuel, Sarah Maximos, David Mazer, Rohan Mittal, Ryan McGinn, Long H Nguyen, Abhilasha Patel, Philippe Richebé, Tarit K Saha, Benjamin E Steinberg, Sonja D Sampson, Duncan J Stewart, Summer Syed, Kimberly Vella, Neil L Wesch, Manoj M Lalu, Canadian Perioperative Anesthesia Clinical Trials Group
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0215221 (2019)
Poor reporting quality may contribute to irreproducibility of results and failed 'bench-to-bedside' translation. Consequently, guidelines have been developed to improve the complete and transparent reporting of in vivo preclinical studies. To examine
Externí odkaz:
https://doaj.org/article/a41cd83c1ab14abfbdd7bdf3fab9263c
Autor:
Benjamin E. Steinberg, Harold A. Silverman, Sergio Robbiati, Manoj K. Gunasekaran, Téa Tsaava, Emily Battinelli, Andrew Stiegler, Chad E. Bouton, Sangeeta S. Chavan, Kevin J. Tracey, Patricio T. Huerta
Publikováno v:
Bioelectronic Medicine, Vol 3, Iss 1, Pp 7-17 (2016)
Abstract The axons of the sensory, or afferent, vagus nerve transmit action potentials to the central nervous system in response to changes in the body’s metabolic and physiological status. Recent advances in identifying neural circuits that regula
Externí odkaz:
https://doaj.org/article/82e7f528c9314d10b323e8a3723b5551
Publikováno v:
Canadian Journal of Anesthesia/Journal canadien d'anesthésie. 69:1025-1032
Legitimate opioid prescriptions can increase the risk of misuse, addiction, and overdose of opioids in children and adolescents. This study aimed to describe the prescribing patterns of discharge opioid analgesics following inpatient visits and to de
Autor:
Yusuke Hirata, Ruiqi Cai, Allen Volchuk, Benjamin E. Steinberg, Atsushi Matsuzawa, Sergio Grinstein, Spencer A. Freeman
The ongoing metabolic and microbicidal pathways that support and protect cellular life generate potentially damaging reactive oxygen species (ROS). To counteract damage, cells express peroxidases, antioxidant enzymes that catalyze the reduction of ox
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c17b94f0cff92e03659da26c76687188
https://doi.org/10.1101/2022.10.31.514557
https://doi.org/10.1101/2022.10.31.514557
Autor:
Yusuke Hirata, Ruiqi Cai, Allen Volchuk, Benjamin E. Steinberg, Yoshiro Saito, Atsushi Matsuzawa, Sergio Grinstein, Spencer A. Freeman
Publikováno v:
Current Biology. 33:1282-1294.e5