Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Benjamin D. Weger"'
Autor:
Oystein Tronstad, Barbara Zangerl, Sue Patterson, Dylan Flaws, Stephanie Yerkovich, Irene Szollosi, Nicole White, Veronica Garcia-Hansen, Francisca Rodriguez Leonard, Benjamin D. Weger, Frédéric Gachon, David Brain, Jayshree Lavana, Carol Hodgson, John F. Fraser
Publikováno v:
Trials, Vol 25, Iss 1, Pp 1-11 (2024)
Abstract Background Intensive care medicine continues to improve, with advances in technology and care provision leading to improved patient survival. However, this has not been matched by similar advances in ICU bedspace design. Environmental factor
Externí odkaz:
https://doaj.org/article/11bde79417264abd8f118de85c0a79d2
Autor:
Lu Ding, Benjamin D. Weger, Jieying Liu, Liyuan Zhou, Yenkai Lim, Dongmei Wang, Ziyan Xie, Jing Liu, Jing Ren, Jia Zheng, Qian Zhang, Miao Yu, Meltem Weger, Mark Morrison, Xinhua Xiao, Frédéric Gachon
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110343- (2024)
Summary: Maternal obesity has long-term effects on offspring metabolic health. Among the potential mechanisms, prior research has indicated potential disruptions in circadian rhythms and gut microbiota in the offspring. To challenge this hypothesis,
Externí odkaz:
https://doaj.org/article/8e36d260e1e04b198d40783de715f116
Autor:
Yohan Bignon, Leonore Wigger, Camille Ansermet, Benjamin D. Weger, Sylviane Lagarrigue, Gabriel Centeno, Fanny Durussel, Lou Götz, Mark Ibberson, Sylvain Pradervand, Manfredo Quadroni, Meltem Weger, Francesca Amati, Frédéric Gachon, Dmitri Firsov
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 8 (2023)
Circadian rhythmicity in renal function suggests rhythmic adaptations in renal metabolism. To decipher the role of the circadian clock in renal metabolism, we studied diurnal changes in renal metabolic pathways using integrated transcriptomic, proteo
Externí odkaz:
https://doaj.org/article/9d19b4af4f6f47d69c7af02c26f827e1
Publikováno v:
Cellular Physiology and Biochemistry, Vol 56, Iss S2, Pp 1-11 (2022)
Externí odkaz:
https://doaj.org/article/a2ccd188b9f844ea975cd79b1dddbb7f
Autor:
Meltem Weger, Benjamin D. Weger, Benjamin Görling, Gernot Poschet, Melek Yildiz, Rüdiger Hell, Burkhard Luy, Teoman Akcay, Tülay Güran, Thomas Dickmeis, Ferenc Müller, Nils Krone
Publikováno v:
EBioMedicine, Vol 36, Iss , Pp 376-389 (2018)
Background: Deficient glucocorticoid biosynthesis leading to adrenal insufficiency is life-threatening and is associated with significant co-morbidities. The affected pathways underlying the pathophysiology of co-morbidities due to glucocorticoid def
Externí odkaz:
https://doaj.org/article/ae10baa3647d4ebc93656935ff620747
Autor:
Anne-Sophie Delbès, Mar Quiñones, Cédric Gobet, Julien Castel, Raphaël G. P. Denis, Jérémy Berthelet, Benjamin D. Weger, Etienne Challet, Aline Charpagne, Sylviane Metairon, Julie Piccand, Marine Kraus, Bettina H. Rohde, John Bial, Elizabeth M. Wilson, Lise-Lotte Vedin, Mirko E. Minniti, Matteo Pedrelli, Paolo Parini, Frédéric Gachon, Serge Luquet
Publikováno v:
Science Advances. 9
The synchronization of circadian clock depends on a central pacemaker located in the suprachiasmatic nuclei. However, the potential feedback of peripheral signals on the central clock remains poorly characterized. To explore whether peripheral organ
Autor:
Sachini Fonseka, Benjamin D. Weger, Meltem Weger, Nick Martel, Thomas E. Hall, Shayli Varasteh Moradi, Christian H. Gabriel, Achim Kramer, Charles Ferguson, Manuel A. Fernández-Rojo, Kirill Alexandrov, Oliver Rawashdeh, Kerrie-Ann McMahon, Frederic Gachon, Robert G Parton
Caveolae are specialized invaginations of the plasma membrane that are formed by the co-assembly of caveolin integral membrane proteins and a cytoplasmic cavin coat complex. Previous work has proposed an interaction of the cavin coat protein, CAVIN3,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c3536061fcaaa34d293da444415f349
https://doi.org/10.1101/2022.10.10.511681
https://doi.org/10.1101/2022.10.10.511681
Autor:
Anne-Sophie Delbès, Mar Quiñones, Cédric Gobet, Julien Castel, Raphaël G. P Denis, Jérémy Berthelet, Benjamin D. Weger, Etienne Challet, Aline Charpagne, Sylviane Metairon, Julie Piccand, Marine Kraus, Bettina H. Rohde, John Bial, Elizabeth M. Wilson, Lise-Lotte Vedin, Mirko E. Minniti, Matteo Pedrelli, Paolo Parini, Frédéric Gachon, Serge Luquet
The circadian clock is an evolutionarily acquired gene network that synchronizes physiological processes to adapt homeostasis to the succession of day and night. While most mammalian cells have a circadian clock, their synchronization at the body-lev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee16c364171cea92c7945d3af4cd90d8
https://doi.org/10.1101/2022.09.08.506890
https://doi.org/10.1101/2022.09.08.506890
Autor:
Céline Jouffe, Benjamin D. Weger, Eva Martin, Florian Atger, Meltem Weger, Cédric Gobet, Divya Ramnath, Aline Charpagne, Delphine Morin-Rivron, Elizabeth E. Powell, Matthew J. Sweet, Mojgan Masoodi, N. Henriette Uhlenhaut, Frédéric Gachon
Publikováno v:
Jouffe, Céline; Weger, Benjamin D; Martin, Eva; Atger, Florian; Weger, Meltem; Gobet, Cédric; Ramnath, Divya; Charpagne, Aline; Morin-Rivron, Delphine; Powell, Elizabeth E; Sweet, Matthew J; Masoodi, Mojgan; Uhlenhaut, N Henriette; Gachon, Frédéric (2022). Disruption of the circadian clock component BMAL1 elicits an endocrine adaption impacting on insulin sensitivity and liver disease. Proceedings of the National Academy of Sciences of the United States of America-PNAS, 119(10), e2200083119. National Academy of Sciences NAS 10.1073/pnas.2200083119
Proc. Natl. Acad. Sci. U.S.A. 119:e2200083119 (2022)
Proc. Natl. Acad. Sci. U.S.A. 119:e2200083119 (2022)
Significance While increasing evidence associates the disruption of circadian rhythms with pathologic conditions, including obesity, type 2 diabetes, and nonalcoholic fatty liver diseases (NAFLD), the involved mechanisms are still poorly described. H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd824578f563e912c709879f9167c0f8
https://boris.unibe.ch/166573/1/pnas.2200083119.pdf
https://boris.unibe.ch/166573/1/pnas.2200083119.pdf
Autor:
Julien Marquis, Felix Naef, Eva Martin, Nagammal Neelagandan, Frédéric Gachon, Cédric Gobet, Benjamin D. Weger
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Protein synthesis is a fundamental and tightly controlled process which allows organisms to respond rapidly to external signals such as nutrient availability or stress conditions. While the initiation step is well studied, the determinan