Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Benjamin D. Cons"'
Autor:
Emiliano Tamanini, Shin Miyamura, Ildiko M. Buck, Benjamin D. Cons, Lee Dawson, Charlotte East, Takashi Futamura, Shintaro Goto, Charlotte Griffiths-Jones, Tetsuya Hashimoto, Tom D. Heightman, Shunpei Ishikawa, Hideki Ito, Yosuke Kaneko, Tatsuya Kawato, Kazumi Kondo, Naoki Kurihara, James M. McCarthy, Yukiko Mori, Tsuyoshi Nagase, Yuichiro Nakaishi, Judith Reeks, Akimasa Sato, Patrick Schöpf, Kuninori Tai, Taichi Tamai, Dominic Tisi, Alison J.-A. Woolford
Publikováno v:
ACS Medicinal Chemistry Letters. 13:1591-1597
Fragment-based ligand discovery was successfully applied to histone deacetylase HDAC2. In addition to the anticipated hydroxamic acid- and benzamide-based fragment screening hits, a low affinity (∼1 mM) α-amino-amide zinc binding fragment was iden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9a51f121f3406b6de752dce46b777833
https://doi.org/10.1021/acsmedchemlett.2c00272
https://doi.org/10.1021/acsmedchemlett.2c00272
Publikováno v:
Journal of Medicinal Chemistry. 65:7476-7488
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dba539a02fb3494e0c41dd1f77740e12
https://doi.org/10.1021/acs.jmedchem.2c00164
https://doi.org/10.1021/acs.jmedchem.2c00164
Publikováno v:
Organic Letters. 15:2046-2049
An efficient strategy for the total synthesis of (-)-blepharocalyxin D and an analogue is described. The key step involves an acid-mediated cascade process in which reaction of methyl 3,3-dimethoxypropanoate with γ,δ-unsaturated alcohols possessing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e9989494902767db4478dbdd4cffc16
https://doi.org/10.1021/ol400736w
https://doi.org/10.1021/ol400736w
Autor:
Christopher D. Bailey, Sophie J. Edwards, Jon D. Elsworth, Tshepo Pheko, Christine L. Willis, Adam J. Bunt, Benjamin D. Cons
Publikováno v:
Angewandte Chemie (International ed. in English). 51(16)
trans-2,8-Dioxabicyclodecanes were prepared in high yield with the creation of up to three stereocenters in a single pot by the acid-mediated reaction of γ,δ-unsaturated alcohols with aldehydes (see scheme, Bn=benzyl). This versatile reaction enabl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9616c9c0e9b965e0e057d0c581a684
https://pubmed.ncbi.nlm.nih.gov/22392806
https://pubmed.ncbi.nlm.nih.gov/22392806
Publikováno v:
Organic Letters; Vol. 15 Issue 8, p2046-2049, 4p