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of 9
pro vyhledávání: '"Benjamin D Harrison"'
Autor:
Benjamin D Harrison, Jordan Hashemi, Maayan Bibi, Rebecca Pulver, Danny Bavli, Yaakov Nahmias, Melanie Wellington, Guillermo Sapiro, Judith Berman
Publikováno v:
PLoS Biology, Vol 12, Iss 3, p e1001815 (2014)
Candida albicans, the most prevalent human fungal pathogen, is generally diploid. However, 50% of isolates that are resistant to fluconazole (FLC), the most widely used antifungal, are aneuploid and some aneuploidies can confer FLC resistance. To ask
Externí odkaz:
https://doaj.org/article/2a1ac39e77b147f2b6b2b890f5c3243d
Autor:
Ching Hua Su, Benjamin D. Harrison, Anja Forche, Meleah A. Hickman, Darren Abbey, Matthew P. Hirakawa, Guisheng Zeng, Yan-Ming Wang, Richard J. Bennett, Yue Wang, Judith Berman
Publikováno v:
Nature. 494:55-59
Candida albicans, the most prevalent human fungal pathogen, is considered to be an obligate diploid that carries recessive lethal mutations throughout the genome. Here we demonstrate that C. albicans has a viable haploid state that can be derived fro
Autor:
Kerry Bloom, Julian Haase, Brittany N. Eldridge, Michael Tsabar, Rebecca M. Hine, James E. Haber, Lila Kaminsky, Chloe E. Snider, Benjamin D. Harrison
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 12, Iss 4, p e1006021 (2016)
PLoS Genetics, Vol 12, Iss 4, p e1006021 (2016)
Transcriptional inactivation of the budding yeast centromere has been a widely used tool in studies of chromosome segregation and aneuploidy. In haploid cells when an essential chromosome contains a single conditionally inactivated centromere (GAL-CE
Autor:
Maayan Bibi, Melanie Wellington, Benjamin D. Harrison, Judith Berman, Danny Bavli, Guillermo Sapiro, Jordan Hashemi, Yaakov Nahmias, Rebecca Pulver
Publikováno v:
PLoS Biology
PLoS Biology, Vol 12, Iss 3, p e1001815 (2014)
PLoS Biology, Vol 12, Iss 3, p e1001815 (2014)
When exposed to the antifungal drug fluconazole, Candida albicans undergoes abnormal growth, forming three-lobed “trimeras.” These aneuploid trimeras turn out genetically variable progeny with varying numbers of chromosomes, increasing the odds o
Autor:
Cory W, Quammen, Alvin C, Richardson, Julian, Haase, Benjamin D, Harrison, Russell M, Taylor, Kerry S, Bloom
Publikováno v:
Eurographics Workshop on Visual Computing for Biomedicine. 2008
Fluorescence microscopy provides a powerful method for localization of structures in biological specimens. However, aspects of the image formation process such as noise and blur from the microscope's point-spread function combine to produce an unintu
The mitotic spindle is a structure that forms during mitosis to help ensure that each daughter cell receives a full complement of genetic material. In metaphase, the spindle contains microtubules that nucleate inward from two opposing poles. Chromoso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc737548555b971d093d5bbb0d72bb7
In budding yeast, we have found that sister rDNA arrays marked with fluorescent probes can be visualized as two distinguishable strands during metaphase. Upon anaphase, these arm loci are drawn into the spindle, where they adopt a cruciform-like stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73c73bb8d6c0712a3bb5b3880311ebd0
https://europepmc.org/articles/PMC2875669/
https://europepmc.org/articles/PMC2875669/
Autor:
Kirk E. Francis, Gregory P. Copenhaver, Sandy Y. Lam, Alexandra L. Bey, Benjamin D. Harrison, Luke E. Berchowitz
Recombination, in the form of cross-overs (COs) and gene conversion (GC), is a highly conserved feature of meiosis from fungi to mammals. Recombination helps ensure chromosome segregation and promotes allelic diversity. Lesions in the recombination m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3141fa0f7db3ec32c0bf094b4d94c48e
https://europepmc.org/articles/PMC1805420/
https://europepmc.org/articles/PMC1805420/
Autor:
Darren Abbey, Richard J. Bennett, Matthew P. Hirakawa, Yue Wang, Judith Berman, Benjamin D. Harrison, Anja Forche, Yan-Ming Wang, Guisheng Zeng, Ching Hua Su, Meleah A. Hickman
Publikováno v:
Nature. 530:242-242
Nature 494, 55–59 (2013); doi: 10.1038/nature11865 In this Article, there were two errors in allele assignments. In the legend and colour key to Fig. 1b, the allele identity (‘a’ and ‘b’) is inadvertently reversed. Figure 1 of this Corrigen