Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Benjamin D A Shennan"'
Autor:
Daniel Rozsar, Alistair J. M. Farley, Iain McLauchlan, Benjamin D. A. Shennan, Ken Yamazaki, Darren J. Dixon
Herein we describe the enantioselective intermolecular conjugate addition of nitroalkanes to unactivated α,β-unsaturated esters, catalyzed by a bifunctional iminophosphorane (BIMP) superbase. The transformation provides the most direct access to ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61c38f2da8629ffca88102755669dd65
https://ora.ox.ac.uk/objects/uuid:edf98957-8434-4fff-9224-98d4cafd385f
https://ora.ox.ac.uk/objects/uuid:edf98957-8434-4fff-9224-98d4cafd385f
Autor:
Benjamin D. A. Shennan, Diana Berheci, Jessica L. Crompton, Timothy A. Davidson, Joshua L. Field, Benedict A. Williams, Darren J. Dixon
Publikováno v:
Chemical Society reviews. 51(14)
Acyclic α-tertiary ethers represent a highly prevalent functionality, common to high-value bioactive molecules, such as pharmaceuticals and natural products, and feature as crucial synthetic handles in their construction. As such their synthesis has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef8d67d4b141e51c076e7a10977ffb0a
https://pubmed.ncbi.nlm.nih.gov/35770619
https://pubmed.ncbi.nlm.nih.gov/35770619
Autor:
Benjamin D A Shennan, Shinya Shiomi, Darren J. Dixon, Dhananjayan Vasu, Ken Yamazaki, Ángel L. Fuentes de Arriba, Trevor A. Hamlin
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, 144(3), 1407-1415. American Chemical Society
Shiomi, S, Shennan, B D A, Yamazaki, K, Fuentes De Arriba, Á L, Vasu, D, Hamlin, T A & Dixon, D J 2022, ' A New Organocatalytic Desymmetrization Reaction Enables the Enantioselective Total Synthesis of Madangamine E ', Journal of the American Chemical Society, vol. 144, no. 3, pp. 1407-1415 . https://doi.org/10.1021/jacs.1c12040
Journal of the American Chemical Society, 144(3), 1407-1415. American Chemical Society
Shiomi, S, Shennan, B D A, Yamazaki, K, Fuentes De Arriba, Á L, Vasu, D, Hamlin, T A & Dixon, D J 2022, ' A New Organocatalytic Desymmetrization Reaction Enables the Enantioselective Total Synthesis of Madangamine E ', Journal of the American Chemical Society, vol. 144, no. 3, pp. 1407-1415 . https://doi.org/10.1021/jacs.1c12040
The enantioselective total synthesis of madangamine E has been completed in 30 steps, enabled by a new catalytic and highly enantioselective desymmetrizing intramolecular Michael addition reaction of a prochiral ketone to a tethered β,β’-disubsti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97e983e92664a19b5bc859b395f9338f
https://doi.org/10.1021/jacs.1c12040
https://doi.org/10.1021/jacs.1c12040
Publikováno v:
Chemical Science
An efficient three-step sequence to afford a valuable class of spirocyclic pyrrolidines is reported. A reductive cleavage/Horner–Wadsworth–Emmons cascade facilitates the spirocyclisation of a range of isoxazolines bearing a distal β-ketophosphon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bb151f9e9dd4483a03c5311265c044f
http://europepmc.org/articles/PMC8162384
http://europepmc.org/articles/PMC8162384
Autor:
Jamie A. Leitch, Darren J. Dixon, Benjamin D A Shennan, Alistair M Boyd, Charmaine Y X Poh, Mia C Callens, Harry B Hicks, Daniya Aynetdinova, Zhong Hui Lim
Publikováno v:
Chemical Society reviews. 50(9)
The selective and efficient C-H methylation of sp2 and sp3 carbon centres has become a powerful transformation in the synthetic toolbox. Due to the potential for profound changes to physicochemical properties attributed to the installation of a "Magi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc425adba21f63fa008f29be982d6ec8
https://pubmed.ncbi.nlm.nih.gov/33690769
https://pubmed.ncbi.nlm.nih.gov/33690769