Zobrazeno 1 - 10
of 228
pro vyhledávání: '"Benjamin D, Simons"'
Autor:
Szu-Hsien Sam Wu, Somi Kim, Heetak Lee, Ji-Hyun Lee, So-Yeon Park, Réka Bakonyi, Isaree Teriyapirom, Natalia Hallay, Sandra Pilat-Carotta, Hans-Christian Theussl, Jihoon Kim, Joo-Hyeon Lee, Benjamin D. Simons, Jong Kyoung Kim, Gabriele Colozza, Bon-Kyoung Koo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Image-based lineage tracing enables tissue turnover kinetics and lineage potentials of different adult cell populations to be investigated. Previously, we reported a genetic mouse model system, Red2Onco, which ectopically expressed mutated o
Externí odkaz:
https://doaj.org/article/74e82422c21f4db19abb68b4b9650f98
Autor:
João Araújo, Benjamin D. Simons, Varghese Peter, Kanad Mandke, Marina Kalashnikova, Annabel Macfarlane, Fiona Gabrielczyk, Angela Wilson, Giovanni M. Di Liberto, Denis Burnham, Usha Goswami
Publikováno v:
Frontiers in Human Neuroscience, Vol 18 (2024)
Slow cortical oscillations play a crucial role in processing the speech amplitude envelope, which is perceived atypically by children with developmental dyslexia. Here we use electroencephalography (EEG) recorded during natural speech listening to id
Externí odkaz:
https://doaj.org/article/50d6e6971cd14291ac5c238152bbe07b
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-11 (2023)
Abstract The mechanisms that regulate the patterning of branched epithelia remain a subject of long-standing debate. Recently, it has been proposed that the statistical organization of multiple ductal tissues can be explained through a local self-org
Externí odkaz:
https://doaj.org/article/f5d2b70b3ad9474baa12e1740a59651f
Autor:
Stephen J. Bush, Rafail Nikola, Seungmin Han, Shinnosuke Suzuki, Shosei Yoshida, Benjamin D. Simons, Anne Goriely
Publikováno v:
Cells, Vol 13, Iss 9, p 742 (2024)
Spermatogenesis involves a complex process of cellular differentiation maintained by spermatogonial stem cells (SSCs). Being critical to male reproduction, it is generally assumed that spermatogenesis starts and ends in equivalent transcriptional sta
Externí odkaz:
https://doaj.org/article/4a8aaecf72c04d5abf6e8bc4b75cf0ee
Autor:
Akram A. Hamed, Daniel J. Kunz, Ibrahim El-Hamamy, Quang M. Trinh, Omar D. Subedar, Laura M. Richards, Warren Foltz, Garrett Bullivant, Matthaeus Ware, Maria C. Vladoiu, Jiao Zhang, Antony M. Raj, Trevor J. Pugh, Michael D. Taylor, Sarah A. Teichmann, Lincoln D. Stein, Benjamin D. Simons, Peter B. Dirks
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
The link between neural development and tumourigenesis in adult glioma remains unclear. Here, the authors monitor the developmental stages of Sox2 + /− stem cells from a mouse model using single-cell RNA sequencing and suggest the acquisition of em
Externí odkaz:
https://doaj.org/article/808d767b32b241cfad002bab2df3ad6b
Autor:
Mareike Damen, Lisa Wirtz, Ekaterina Soroka, Houda Khatif, Christian Kukat, Benjamin D. Simons, Hisham Bazzi
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-16 (2021)
How the developing skin epidermis is transformed from a simple single-layered epithelium to a complex and stratified barrier is still an open question. Here, the authors provide a model based on high proliferation and delamination of the keratinocyte
Externí odkaz:
https://doaj.org/article/a8d8b4dfc80449d585d4094cbc088097
Autor:
Magdalena K. Sznurkowska, Edouard Hannezo, Roberta Azzarelli, Lemonia Chatzeli, Tatsuro Ikeda, Shosei Yoshida, Anna Philpott, Benjamin D. Simons
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
The cellular basis of islet morphogenesis and fate allocation remain unclear. Here, the authors use a R26-CreER-R26R-Confetti mouse line to follow quantitatively the clonal dynamics of islet formation showing how, during the secondary transition, isl
Externí odkaz:
https://doaj.org/article/2516bc6a95c0469cbc1e4e1c8a53f059
Autor:
Toshinori Nakagawa, David J. Jörg, Hitomi Watanabe, Seiya Mizuno, Seungmin Han, Tatsuro Ikeda, Yoshiki Omatsu, Keiko Nishimura, Miyako Fujita, Satoru Takahashi, Gen Kondoh, Benjamin D. Simons, Shosei Yoshida, Takashi Nagasawa
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109875- (2021)
Summary: In mouse testis, a heterogeneous population of undifferentiated spermatogonia (Aundiff) harbors spermatogenic stem cell (SSC) potential. Although GFRα1+ Aundiff maintains the self-renewing pool in homeostasis, the functional basis of hetero
Externí odkaz:
https://doaj.org/article/65978c133f0e40fea4fb9cba4e4d510d
Publikováno v:
Biology Open, Vol 10, Iss 2 (2021)
Emerging three-dimensional (3D) cultures of glioblastoma are becoming powerful models to study glioblastoma stem cell behavior and the impact of cell–cell and cell–microenvironment interactions on tumor growth and invasion. Here we describe a met
Externí odkaz:
https://doaj.org/article/79a7a530a9274bcc9ff57f7b7f97a722
Autor:
Yicheng Wu, Sara Bottes, Roberto Fisch, Cinzia Zehnder, John Darby Cole, Gregor-Alexander Pilz, Fritjof Helmchen, Benjamin D. Simons, Sebastian Jessberger
Publikováno v:
Nature Aging. 3:380-390
Neural stem cells (NSCs) generate new neurons throughout life in the mammalian hippocampus1. Advancing age leads to a decline in neurogenesis, which is associated with impaired cognition2,3. The cellular mechanisms causing reduced neurogenesis with a