Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Benjamin Craske"'
Publikováno v:
Open Biology, Vol 12, Iss 3 (2022)
CENP-E is a large kinesin motor protein which plays pivotal roles in mitosis by facilitating chromosome capture and alignment, and promoting microtubule flux in the spindle. So far, it has not been possible to obtain active human CENP-E to study its
Externí odkaz:
https://doaj.org/article/5c1c30fa157841c3baf37913e8e01ba4
Phosphorylation controls spatial and temporal activities of motor-PRC1 complexes to complete mitosis
During mitosis, spindle architecture alters as chromosomes segregate to daughter cells. The microtubule crosslinker Protein Required for Cytokinesis 1 (PRC1) is essential for spindle stability, chromosome segregation and completion of cytokinesis, bu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2aa563a2db0c766e27b5fba616830beb
https://doi.org/10.1101/2023.03.11.531660
https://doi.org/10.1101/2023.03.11.531660
Autor:
Julie P.I. Welburn, Benjamin Craske
Publikováno v:
Essays in Biochemistry
Craske, B & Welburn, J 2020, ' Leaving no-one behind : How CENP-E facilitates chromosome alignment ', Essays in biochemistry . https://doi.org/10.1042/EBC20190073
Craske, B & Welburn, J 2020, ' Leaving no-one behind : How CENP-E facilitates chromosome alignment ', Essays in biochemistry . https://doi.org/10.1042/EBC20190073
Chromosome alignment and biorientation is essential for mitotic progression and genomic stability. Most chromosomes align at the spindle equator in a motor-independent manner. However, a subset of polar kinetochores fail to bi-orient and require a mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::530fc24c3e5dc657e1f1a91dd2c2dced
https://doi.org/10.1042/ebc20190073
https://doi.org/10.1042/ebc20190073