Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Benjamin Chaik Meng Yeo"'
Autor:
Claire M. Naftalin, Rupangi Verma, Meera Gurumurthy, Kim Hor Hee, Qingshu Lu, Benjamin Chaik Meng Yeo, Kin Hup Tan, Wenwei Lin, Buduo Yu, Kok Yong Seng, Lawrence Soon-U Lee, Nicholas I. Paton
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Abstract COX-2 inhibition may be of benefit in the treatment of tuberculosis (TB) through a number of pathways including efflux pump inhibition (increasing intracellular TB drug levels) and diverse effects on inflammation and the immune response. We
Externí odkaz:
https://doaj.org/article/42cbd61d772947248c58c2e871ff77ab
Autor:
Kim Hor Hee, Kin Hup Tan, Nicholas I. Paton, Lawrence S. Lee, Rupangi Verma, Meera Gurumurthy, Buduo Yu, Wenwei Lin, Qingshu Lu, Kok Yong Seng, Benjamin Chaik Meng Yeo, Claire M. Naftalin
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-8 (2018)
COX-2 inhibition may be of benefit in the treatment of tuberculosis (TB) through a number of pathways including efflux pump inhibition (increasing intracellular TB drug levels) and diverse effects on inflammation and the immune response. We investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b77bbfd183258e6546849b3dd6d690b3
https://pubmed.ncbi.nlm.nih.gov/30202030
https://pubmed.ncbi.nlm.nih.gov/30202030
Autor:
Meera Gurumurthy, Matthew D. Zimmerman, Kin Hup Tan, Buduo Yu, Wenwei Lin, Nicholas I. Paton, Benjamin Chaik Meng Yeo, Qingshu Lu, Rupangi Verma, Claire M. Naftalin, Véronique Dartois
Publikováno v:
Antimicrobial Agents and Chemotherapy. 61
Coadministering pyrazinamide (PZA) with the xanthine oxidase inhibitor allopurinol increases systemic levels of the active metabolite, pyrazinoic acid (POA), but the effects on bactericidal activity against tuberculosis are unknown. We randomized hea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7dfb223103fb3f4b7ba3f18ae260a485
https://doi.org/10.1128/aac.00482-17
https://doi.org/10.1128/aac.00482-17
Autor:
Nicholas I. Paton, Mark Kheng Chuan Tan, Rupangi Verma, Paul Edward Hutchinson, Benjamin Chaik Meng Yeo, Gail B Cross, Qingshu Lu
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216616 (2019)
PLoS ONE
PLoS ONE
We investigated the contribution of host immune cells to bacterial killing in a whole-blood bactericidal activity (WBA) assay, an ex vivo model used to test efficacy of drugs against mycobacterium tuberculosis (Mtb). We performed WBA assays with immu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df070bb5ad27711652ce808758af9a6d
https://doi.org/10.1371/journal.pone.0216616
https://doi.org/10.1371/journal.pone.0216616