Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Benjamin Causton"'
Autor:
Anna Klimovskaia, Beat Thöny, Ralph Fingerhut, Jakub Krijt, Jean-Marc Nuoffer, Gabriella Allegri, Hiu Man Grisch-Chan, Viktor Kožich, Benjamin Causton, Tanja Scherer, Johannes Häberle, Sereina Deplazes, Carmen Diez-Fernandez, Nicole Rimann, Jonathan W. Leff
Publikováno v:
Journal of Inherited Metabolic Disease. 42:1064-1076
The most common ureagenesis defect is X-linked ornithine transcarbamylase (OTC) deficiency which is a main target for novel therapeutic interventions. The spf ash mouse model carries a variant (c.386G>A, p.Arg129His) that is also found in patients. M
Autor:
Gabriella, Allegri, Sereina, Deplazes, Nicole, Rimann, Benjamin, Causton, Tanja, Scherer, Jonathan W, Leff, Carmen, Diez-Fernandez, Anna, Klimovskaia, Ralph, Fingerhut, Jakub, Krijt, Viktor, Kožich, Jean-Marc, Nuoffer, Hiu M, Grisch-Chan, Beat, Thöny, Johannes, Häberle
Publikováno v:
Journal of inherited metabolic diseaseREFERENCES. 42(6)
The most common ureagenesis defect is X-linked ornithine transcarbamylase (OTC) deficiency which is a main target for novel therapeutic interventions. The spf
Autor:
Benjamin Causton, Benjamin D. Medoff, Jayaraj Rajagopal, Ramnik J. Xavier, Katherine Discipio, Josalyn L. Cho, Ana Pardo-Saganta, Tristan Kooistra, Jacob Gillis
Publikováno v:
American journal of respiratory cell and molecular biology. 59(6)
The airway epithelial cell (AEC) response to allergens helps initiate and propagate allergic inflammation in asthma. CARMA3 is a scaffold protein that mediates G protein-coupled receptor-induced NF-κB activation in airway epithelium. In this study,
Autor:
Ana Pardo-Saganta, Jayaraj Rajagopal, Khristianna Jones, Ramnik J. Xavier, Benjamin Causton, Josalyn L. Cho, Benjamin D. Medoff, Ravisankar A. Ramadas
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 195(2)
Innate immune responses to allergens by airway epithelial cells (AECs) help initiate and propagate the adaptive immune response associated with allergic airway inflammation in asthma. Activation of the transcription factor NF-κB in AECs by allergens
Publikováno v:
The Journal of allergy and clinical immunology. 129(4)
Background—IL-9-secreting (TH9) T cells are thought to represent a distinct T-cell subset. However, evidence for their functionality in disease is uncertain. Objective—To define a functional phenotype for TH9-driven pathology in vivo. Methods—W
Autor:
Sara A. Mathie, Clare M. Lloyd, Jenna R. Murdoch, Christopher P. Thomas, Benjamin Causton, Lisa G. Gregory, F. M. Priest, Valerie B. O'Donnell, Diana Quint
Background Inhaled house dust mite (HDM) results in T-helper (TH) 2 type pathology in unsensitized mice, in conjunction with airway hyperreactivity and airway remodelling. However, the pulmonary cytokine and chemokine profile has not been reported. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ed5c110b76e723b32d8ca2facb2efe8
https://europepmc.org/articles/PMC3385347/
https://europepmc.org/articles/PMC3385347/