Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Benjamin C. Milgram"'
Autor:
Konstantinos Afratis, Joseph M. Bateman, Benjamin F. Rahemtulla, Oliver Hughes, Benjamin C. Milgram, Thomas A. Mulhern, Eric P. A. Talbot
Publikováno v:
Organic Letters. 25:461-465
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82706862490ae4b8607a9b06a2739107
https://doi.org/10.1021/acs.orglett.2c03889
https://doi.org/10.1021/acs.orglett.2c03889
Autor:
John R, Butler, Gwenaella, Rescourio, Benjamin C, Milgram, Robert S, Foti, Thomas, Kornecook, Joseph, Ligutti, Bryan D, Moyer, Kristin, Taborn, Beth D, Youngblood, Violeta, Yu, Roman, Shimanovich, Alessandro, Boezio, Matthew, Weiss
Publikováno v:
Bioorganicmedicinal chemistry letters. 73
Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::026ead5bb43373a0b3209260097690d4
https://pubmed.ncbi.nlm.nih.gov/35850422
https://pubmed.ncbi.nlm.nih.gov/35850422
Autor:
Jessica Able, Benjamin C. Milgram, Loren Berry, Melanie Cooke, Liyue Huang, John Butler, Hongbing Huang, Violeta Yu, Kristin Taborn, John D. Roberts, Steven Altmann, Margaret Y. Chu-Moyer, John Yeoman, Jean Wang, Roman Shimanovich, Russell Graceffa, Matthew Weiss, Thomas Kornecook, Christopher P Ilch, Bryan D. Moyer, Christiane Boezio, Isaac E. Marx, Brian A. Sparling, Emily A. Peterson, Gwen Rescourio, Charles Kreiman, Elma Feric Bojic, Karina R. Vaida, Angel Guzman-Perez, Dawn Zhu, Hua Gao, Laurie B. Schenkel, Michael Jarosh, Hanh Nho Nguyen, Joseph Ligutti, Alessandro Boezio, Hakan Gunaydin, Daniel S. La, Thomas Dineen, Robert T. Fremeau, Robert S. Foti, Min-Hwa Jasmine Lin, Erin F. DiMauro, John Stellwagen
Publikováno v:
Journal of Medicinal Chemistry. 60:5990-6017
Because of its strong genetic validation, NaV1.7 has attracted significant interest as a target for the treatment of pain. We have previously reported on a number of structurally distinct bicyclic heteroarylsulfonamides as NaV1.7 inhibitors that demo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb6062704d531ce83c1a6122ecc44600
https://doi.org/10.1021/acs.jmedchem.6b01850
https://doi.org/10.1021/acs.jmedchem.6b01850
Autor:
Laurie B, Schenkel, Erin F, DiMauro, Hanh N, Nguyen, Nagasree, Chakka, Bingfan, Du, Robert S, Foti, Angel, Guzman-Perez, Michael, Jarosh, Daniel S, La, Joseph, Ligutti, Benjamin C, Milgram, Bryan D, Moyer, Emily A, Peterson, John, Roberts, Violeta L, Yu, Matthew M, Weiss
Publikováno v:
Bioorganicmedicinal chemistry letters. 27(16)
The Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::feccab44327957064eb9a4c9ed77e708
https://pubmed.ncbi.nlm.nih.gov/28684121
https://pubmed.ncbi.nlm.nih.gov/28684121
Autor:
Russell F, Graceffa, Alessandro A, Boezio, Jessica, Able, Steven, Altmann, Loren M, Berry, Christiane, Boezio, John R, Butler, Margaret, Chu-Moyer, Melanie, Cooke, Erin F, DiMauro, Thomas A, Dineen, Elma, Feric Bojic, Robert S, Foti, Robert T, Fremeau, Angel, Guzman-Perez, Hua, Gao, Hakan, Gunaydin, Hongbing, Huang, Liyue, Huang, Christopher, Ilch, Michael, Jarosh, Thomas, Kornecook, Charles R, Kreiman, Daniel S, La, Joseph, Ligutti, Benjamin C, Milgram, Min-Hwa Jasmine, Lin, Isaac E, Marx, Hanh N, Nguyen, Emily A, Peterson, Gwen, Rescourio, John, Roberts, Laurie, Schenkel, Roman, Shimanovich, Brian A, Sparling, John, Stellwagen, Kristin, Taborn, Karina R, Vaida, Jean, Wang, John, Yeoman, Violeta, Yu, Dawn, Zhu, Bryan D, Moyer, Matthew M, Weiss
Publikováno v:
Journal of medicinal chemistry. 60(14)
Because of its strong genetic validation, Na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b8ea84d65ab7dd59414c7bfc36426140
https://pubmed.ncbi.nlm.nih.gov/28324649
https://pubmed.ncbi.nlm.nih.gov/28324649
Publikováno v:
Journal of the American Chemical Society. 134:16765-16772
Total syntheses of HMP-Y1, atrop-HMP-Y1, hibarimicinone, atrop-hibarimicinone, and HMP-P1 are described using a two-directional synthesis strategy. A novel benzyl fluoride Michael–Claisen reaction sequence was developed to construct the complete ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab42d04f44fe1c8cf7d36d145fbb2314
https://doi.org/10.1021/ja307207q
https://doi.org/10.1021/ja307207q
Autor:
Karl A. Scheidt, Steven M. Richter, W. Robert Scheidt, Katrine Eskildsen, Benjamin C. Milgram
Publikováno v:
The Journal of Organic Chemistry. 72:3941-3944
The synthesis of N-acyl 3,4-disubstituted pyrroles can be accomplished directly from hydrazine and an aldehyde via a Piloty−Robinson pyrrole synthesis. The use of microwave radiation for the cyclization and pyrrole formation greatly reduces the tim
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::875613081155ed985d92d3142e37fbb7
https://doi.org/10.1021/jo070389+
https://doi.org/10.1021/jo070389+
Publikováno v:
Organic Letters. 6:3977-3980
[reaction: see text] A general synthesis of acylsilanes from the corresponding morpholine amides and silyllithium species is described. The use of morpholine amides is economical and prevents over-addition by the silyl nucleophile. The procedure clea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5aa785b336f6040f905448c250f0c85
https://doi.org/10.1021/ol0483854
https://doi.org/10.1021/ol0483854
Publikováno v:
Organic letters. 13(24)
A gram-scale enantiospecific synthesis of the A'B'-subunit of angelmicin B is reported. The synthesis involves a Lewis acid catalyzed contrasteric Diels-Alder reaction and a tandem silyl zincate 1,6-addition/enolate oxidation sequence.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e9acb7cff51067e018ad011060b1a86
https://pubmed.ncbi.nlm.nih.gov/22084899
https://pubmed.ncbi.nlm.nih.gov/22084899
Publikováno v:
Organic Syntheses
1-Morpholinopropan-1-one Morpholine Propanoyl chloride Chlorodimethylphenylsilane 1-(Dimethyl(phenyl)silyl)propan-1-one Keywords: morpholine amides; acylsilanes; brook rearrangement; annulation reactions; carbonyl carbon-silicon bond; waste disposal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f79bfd0783e27d1cba921103e31a6604
https://doi.org/10.1002/0471264229.os084.03
https://doi.org/10.1002/0471264229.os084.03
