Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Benjamin C. Dibling"'
Autor:
Benjamin C. Dibling, Anning Lin
Publikováno v:
Aging Cell. 1:112-116
Age-associated changes in apoptotic rates have been observed in a number of different tissues. While the implications of these findings remain unclear, a better understanding of how apoptosis is regulated may further our understanding of the aging pr
Publikováno v:
Oncogene. 21:809-824
The mechanism of bFGF-induced cell death in tumours of the Ewing's sarcoma family (ESFT) has been investigated. bFGF-induces phosphorylation of FGFr 1 and activation of Ras/ERK in ESFT cells that die when exposed to bFGF. Induction of cell death was
Definitive erythropoiesis occurs in islands composed of a central macrophage in contact with differentiating erythroblasts. Erythroid maturation including enucleation can also occur in the absence of macrophages both in vivo and in vitro. We reported
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::587ef4768da03d17e6161db2abe6a21f
https://europepmc.org/articles/PMC1976369/
https://europepmc.org/articles/PMC1976369/
Autor:
Benjamin T. Spike, Kay F. Macleod, Paul T. Schumacker, James R. Knabb, Kristin Tracy, Benjamin C. Dibling
Hypoxia and nutrient deprivation are environmental stresses governing the survival and adaptation of tumor cells in vivo. We have identified a novel role for the Rb tumor suppressor in protecting against nonapoptotic cell death in the developing mous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::566d830a882b9bb0b06d01a9247b4b7a
https://europepmc.org/articles/PMC1952167/
https://europepmc.org/articles/PMC1952167/
Autor:
James Marvin, Benjamin T. Spike, Alexandra Dirlam, Tyler Jacks, Benjamin C. Dibling, Kay F. Macleod, Bart O. Williams
The retinoblastoma tumor suppressor gene plays important roles in cell cycle control, differentiation and survival during development and is functionally inactivated in most human cancers. Early studies using gene targeting in mice suggested a critic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0f8aaf951e812f8008108af12bddea
https://europepmc.org/articles/PMC524396/
https://europepmc.org/articles/PMC524396/
Publikováno v:
The Journal of biological chemistry. 279(46)
Basic fibroblast growth factor (bFGF) induces cell death in cells of the Ewing's sarcoma family of tumors in vivo and in vitro. In this study we demonstrate that this is dependent on the rapid and sustained activation of p38(MAPK), in contrast to the
Publikováno v:
Current opinion in geneticsdevelopment. 14(1)
For a gene whose existence was first postulated in 1971, was cloned in 1986 and whose functions have been extensively characterized ever since, you might be inclined to think there was not much new to report regarding the retinoblastoma tumor suppres
Autor:
Nicole H. Purcell, Yuzuru Minemoto, Benjamin C. Dibling, Anning Lin, Guillin Tang, Michael Karin, Zhi-Wei Li
Publikováno v:
Nature. 414(6861)
The proinflammatory cytokine tumour necrosis factor-alpha (TNF-alpha) regulates immune responses, inflammation and programmed cell death (apoptosis). The ultimate fate of a cell exposed to TNF-alpha is determined by signal integration between its dif