Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Benjamin C. Chandler"'
Autor:
Andrea M. Pesch, Nicole H. Hirsh, Anna R. Michmerhuizen, Kassidy M. Jungles, Kari Wilder-Romans, Benjamin C. Chandler, Meilan Liu, Lynn M. Lerner, Charles A. Nino, Connor Ward, Erin F. Cobain, Theodore S. Lawrence, Lori J. Pierce, James M. Rae, Corey W. Speers
Publikováno v:
JCI Insight, Vol 7, Iss 3 (2022)
Standard radiation therapy (RT) does not reliably provide locoregional control for women with multinode-positive breast cancer and triple-negative breast cancer (TNBC). We hypothesized that CDK4/6 inhibition (CDK4/6i) would increase the radiosensitiv
Externí odkaz:
https://doaj.org/article/a01908851a6948f19c0bebb697957f52
Autor:
Benjamin C. Chandler, Corey Speers
Publikováno v:
Molecular & Cellular Oncology, Vol 7, Iss 3 (2020)
Basal-like breast cancers have the highest rates of locoregional recurrence after radiation. By correlating gene expression with early locoregional recurrence, we nominate TTK protein kinase as a mediator of radioresistance. TTK inhibition radiosensi
Externí odkaz:
https://doaj.org/article/be37f1d0b8e146a5b0293a1f33bd6544
Autor:
Corey W. Speers, James M. Rae, Lori J. Pierce, Kassidy M. Jungles, Charles A. Nino, Cassandra L. Ritter, Tanner Ward, Meilan Liu, Kari Wilder-Romans, Nicole H. Hirsh, Hannah M. Carter, Anna R. Michmerhuizen, Benjamin C. Chandler, Andrea M. Pesch
Supplemental Figures (8) and Tables
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66aea7f468b7f4de3d6c90ef69c65486
https://doi.org/10.1158/2767-9764.22545201
https://doi.org/10.1158/2767-9764.22545201
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Higher doses of olaparib are sufficient to inhibit PAR formation in BRCA1-mutant SUM-149 cells. At higher concentrations of olaparib (1μM), combination treatment of PARP1 inhibition and radiation decreases PAR in a comparable manner to lower doses o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::623d55d5dd22fc6feaa49169a3f1f0b6
https://doi.org/10.1158/1535-7163.22518895
https://doi.org/10.1158/1535-7163.22518895
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Extended methods for immunohistochemistry. Antibodies used in immunohistochemistry experiments are listed with each of the corresponding dilutions, retrieval techniques, and positive controls.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1dec1ab52d25aad68186ffb5ea9a1a23
https://doi.org/10.1158/1535-7163.22518883
https://doi.org/10.1158/1535-7163.22518883
Autor:
Corey Speers, Reshma Jagsi, Lori J. Pierce, Shyam Nyati, Meilan Liu, Cassandra L. Ritter, Nicole Hirsh, Amanda Zhang, Dafydd G. Thomas, Eric Olsen, Meleah Cameron, Kari Wilder-Romans, Benjamin C. Chandler, Leah Moubadder, Andrea M. Pesch, Anna R. Michmerhuizen
Sustained locoregional control of disease is a significant issue in patients with inflammatory breast cancer (IBC), with local control rates of 80% or less at 5 years. Given the unsatisfactory outcomes for these patients, there is a clear need for in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08ab813eb94ed0666f01ed7b66b76c82
https://doi.org/10.1158/1535-7163.c.6542167
https://doi.org/10.1158/1535-7163.c.6542167
Autor:
Corey W. Speers, James M. Rae, Lori J. Pierce, José M. Larios, Christina L. Gersch, Meilan Liu, Kari Wilder-Romans, Marlie P. Androsiglio, Cassandra L. Ritter, Anna R. Michmerhuizen, Benjamin C. Chandler, Nicole H. Hirsh, Andrea M. Pesch
Supplementary Materials and Methods Section
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e3ea25ec72c800fc37fd2c1ed36ab9a
https://doi.org/10.1158/1078-0432.22476420
https://doi.org/10.1158/1078-0432.22476420
Autor:
Corey W. Speers, James M. Rae, Lori J. Pierce, José M. Larios, Christina L. Gersch, Meilan Liu, Kari Wilder-Romans, Marlie P. Androsiglio, Cassandra L. Ritter, Anna R. Michmerhuizen, Benjamin C. Chandler, Nicole H. Hirsh, Andrea M. Pesch
Supplementary Figures 1-9 and Supplementary Tables 1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13de2664e8c85393dd935a41d535216a
https://doi.org/10.1158/1078-0432.22476426.v1
https://doi.org/10.1158/1078-0432.22476426.v1
Autor:
Corey W. Speers, James M. Rae, Lori J. Pierce, José M. Larios, Christina L. Gersch, Meilan Liu, Kari Wilder-Romans, Marlie P. Androsiglio, Cassandra L. Ritter, Anna R. Michmerhuizen, Benjamin C. Chandler, Nicole H. Hirsh, Andrea M. Pesch
Purpose:Cyclin-dependent kinase 4/6 (CDK4/6) inhibitors have improved progression-free survival for metastatic, estrogen receptor–positive (ER+) breast cancers, but their role in the nonmetastatic setting remains unclear. We sought to understand th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::352f4e1af5ba38fbb7d886201cb5ba6b
https://doi.org/10.1158/1078-0432.c.6529395.v1
https://doi.org/10.1158/1078-0432.c.6529395.v1
Autor:
Corey W. Speers, James M. Rae, Lori J. Pierce, José M. Larios, Christina L. Gersch, Meilan Liu, Kari Wilder-Romans, Marlie P. Androsiglio, Cassandra L. Ritter, Anna R. Michmerhuizen, Benjamin C. Chandler, Nicole H. Hirsh, Andrea M. Pesch
Captions for Supplementary Figures 1-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::509737f1275b38525ea1b070ea5e1046
https://doi.org/10.1158/1078-0432.22476423.v1
https://doi.org/10.1158/1078-0432.22476423.v1