Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Benjamin C, Cossins"'
Autor:
Helin Tercan, Benjamin C. Cossins, Rosanne C. van Deuren, Joost H. W. Rutten, Leo A. B. Joosten, Mihai G. Netea, Alexander Hoischen, Siroon Bekkering, Niels P. Riksen
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 2 (2024)
Background Obesity is accompanied by dysregulated inflammation, which can contribute to vasculometabolic complications including metabolic syndrome and atherosclerosis. Recently, clonal hematopoiesis of indeterminate potential (CHIP) has emerged as a
Externí odkaz:
https://doaj.org/article/386a3cf3b948494e8e35866013b4781d
Autor:
Jan-Quinten Mol, Julia van Tuijl, Siroon Bekkering, Charlotte D.C.C. van der Heijden, Sander A.J. Damen, Benjamin C. Cossins, Liesbeth van Emst, Tim M. Nielen, Laura Rodwell, Yang Li, Gheorghe A.M. Pop, Mihai G. Netea, Niels van Royen, Niels P. Riksen, Saloua El Messaoudi
Publikováno v:
iScience, Vol 26, Iss 7, Pp 107183- (2023)
Summary: An increasing number of patients develop an atherothrombotic myocardial infarction (MI) in the absence of standard modifiable risk factors (SMuRFs). Monocytes and macrophages regulate the development of atherosclerosis, and monocytes can ado
Externí odkaz:
https://doaj.org/article/fc49a727a85442d1b19e4779f98bee00
Autor:
Usman Khalid, Robert H. Jenkins, Robert Andrews, Gilda Pino-Chavez, Benjamin C. Cossins, Rafael Chavez, Timothy Bowen, Donald J. Fraser
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Ischemic preconditioning (IPC) is effective in limiting subsequent ischemic acute kidney injury in experimental models. MicroRNAs are an important class of post-transcriptional regulator and show promise as biomarkers of kidney injury. We ev
Externí odkaz:
https://doaj.org/article/f300b59f825445b7aca92d3fdb870348
Autor:
Benjamin C Cossins, Inge van den Munckhof, Joost H W Rutten, Marinette van der Graaf, Rinke Stienstra, Leo A B Joosten, Mihai G Netea, Yang Li, Niels P Riksen
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism.
Context Adipose tissue (AT) inflammation predisposes to insulin resistance and metabolic syndrome in obesity. Objective To investigate the association between adipocyte size, AT inflammation, systemic inflammation, and metabolic and atherosclerotic c
Autor:
David Millrine, Ana Cardus Figueras, Javier Uceda Fernandez, Robert Andrews, Barbara Szomolay, Benjamin C Cossins, Christopher M. Rice, Jasmine Li, Victoria J Tyrrell, Louise McLeod, Peter Holmans, Valerie B O’Donnell, Philip R Taylor, Stephen J. Turner, Brendan J. Jenkins, Gareth W Jones, Nicholas Topley, Nigel M Williams, Simon A Jones
Cytokines that signal via STAT1 and STAT3 transcription factors instruct decisions affecting tissue homeostasis, anti-microbial host defense, and inflammation-induced tissue injury. To understand the coordination of these activities, we applied RNA-s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1d5774d6c58ef55a8bb90270e61b8e58
https://doi.org/10.1101/2022.07.18.499157
https://doi.org/10.1101/2022.07.18.499157
Autor:
Gilda Pino-Chavez, Robert Andrews, Rafael Chavez, Timothy Bowen, Donald James Fraser, Benjamin C. Cossins, Usman Khalid, Robert H. Jenkins
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Ischemic preconditioning (IPC) is effective in limiting subsequent ischemic acute kidney injury in experimental models. MicroRNAs are an important class of post-transcriptional regulator and show promise as biomarkers of kidney injury. We evaluated t
Autor:
Simon Arnett Jones, Jasmine Li, Florian Wiede, Michael J. Townsend, Gareth W. Jones, Xiao Liu, Costantino Pitzalis, Robert Andrews, Jason Peter Twohig, Alicia Derrac Soria, Philip R. Taylor, Javier Uceda Fernandez, Tony Tiganis, Barbara Szomolay, David Hill, Myles Lewis, Chris Pepper, Benjamin C. Cossins, Nigel Williams, Ana Cardus Figueras, David Millrine
Publikováno v:
Twohig, J, Figueras, A C, Andrews, R, Wiede, F, Cossins, B, Soria, A D, Lewis, M, Townsend, M, Millrine, D, Hill, D, Fernandez, J U, Liu, X, Szomolay, B, Pepper, C, Taylor, P, Pitzalis, C, Tiganis, T, Williams, N, Jones, G, Jones, S & Li, J 2019, ' Activation of naïve CD4 + T cells re-tunes STAT1 signaling to deliver unique cytokine responses in memory CD4 + T cells ', Nature Immunology, vol. 20, no. 4, pp. 458-470 . https://doi.org/10.1038/s41590-019-0350-0
The cytokine IL-6 controls the survival, proliferation and effector characteristics of lymphocytes through activation of the transcription factors STAT1 and STAT3. While STAT3 activity is an ever-present feature of IL-6 signaling in CD4 + T cells, pr
Autor:
Jason P, Twohig, Ana, Cardus Figueras, Robert, Andrews, Florian, Wiede, Benjamin C, Cossins, Alicia, Derrac Soria, Myles J, Lewis, Michael J, Townsend, David, Millrine, Jasmine, Li, David G, Hill, Javier, Uceda Fernandez, Xiao, Liu, Barbara, Szomolay, Christopher J, Pepper, Philip R, Taylor, Costantino, Pitzalis, Tony, Tiganis, Nigel M, Williams, Gareth W, Jones, Simon A, Jones
Publikováno v:
Nature immunology
The cytokine IL-6 controls the survival, proliferation and effector characteristics of lymphocytes through activation of the transcription factors STAT1 and STAT3. While STAT3 activity is an ever-present feature of IL-6 signaling in CD4+ T cells, pri