Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Benjamin Barsi-Rhyne"'
Publikováno v:
eLife, Vol 11 (2022)
β-Arrestins are master regulators of cellular signaling that operate by desensitizing ligand-activated G-protein-coupled receptors (GPCRs) at the plasma membrane and promoting their subsequent endocytosis. The endocytic activity of β-arrestins is l
Externí odkaz:
https://doaj.org/article/5b527990b279409ebe599b33a0fb0974
Autor:
Daichi Kamiyama, Sayaka Sekine, Benjamin Barsi-Rhyne, Jeffrey Hu, Baohui Chen, Luke A. Gilbert, Hiroaki Ishikawa, Manuel D. Leonetti, Wallace F. Marshall, Jonathan S. Weissman, Bo Huang
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-9 (2016)
Tagging proteins with fluorescent proteins is a powerful method for both imaging and non-imaging applications. Here the authors use the eleventh β-strand of sfGFP and sfCherry as epitope tags for multicolour imaging and amplified signals by tandem a
Externí odkaz:
https://doaj.org/article/1050b0556bdb46ffae8a8e6c60a400b8
Autor:
John Janetzko, Ryoji Kise, Benjamin Barsi‐Rhyne, Dirk H. Siepe, Franziska M. Heydenreich, Matthieu Masureel, Kouki Kawakami, K. C. Garcia, Mark Zastrow, Asuka Inoue, Brian K. Kobilka
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61af36971992f108e0a5ac3ee1f54248
https://doi.org/10.1096/fasebj.2022.36.s1.r6320
https://doi.org/10.1096/fasebj.2022.36.s1.r6320
Autor:
John Janetzko, Ryoji Kise, Benjamin Barsi-Rhyne, Dirk H. Siepe, Franziska M. Heydenreich, Kouki Kawakami, Matthieu Masureel, Shoji Maeda, K. Christopher Garcia, Mark von Zastrow, Asuka Inoue, Brian K. Kobilka
Publikováno v:
Cell
Binding of arrestin to phosphorylated G protein-coupled receptors (GPCRs) is crucial for modulating signaling. Once internalized, some GPCRs remain complexed with β-arrestins, while others interact only transiently; this difference affects GPCR sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b0080dd89b74624622aa3a8a342956a
Autor:
Un Seng Chio, Ming Sun, Adolfo García-Sastre, R.A. Saunders, Niv Dobzinski, Jiahao Liang, Vladislav Belyy, Peter Walter, Caleigh M. Azumaya, Beth S. Zha, Fei Li, Morgane Boone, Kris M. White, Yuwei Liu, Kaitlin Schaefer, Frank R. Moss, Aashish Manglik, Nevan J. Krogan, Michael C. Thompson, Nick Hoppe, Alexandrea N. Rizo, Axel F. Brilot, Danielle L. Swaney, S. Dickinson, Corie Y. Ralston, Bryan Faust, Devan Diwanji, A.W. Barile-Hill, Camille R. Simoneau, Smriti Sangwan, Sayan Gupta, Benjamin Barsi-Rhyne, Mingliang Jin, Veronica V. Rezelj, Huong T. Kratochvil, Silke Nock, David Bulkley, Kristoffer E. Leon, Marco Vignuzzi, Sergei Pourmal, Henry C. Nguyen, Thomas H. Pospiech, Gregory E. Merz, Raphael Trenker, Cynthia M. Chio, Yanxin Liu, Kaihua Zhang, Meghna Gupta, Aditya A. Anand, Cristina Puchades, M. Zimanyi, Amber M. Smith, Michael Schoof, Christian B. Billesbølle, Melanie Ott, Ishan Deshpande
Publikováno v:
Science (New York, N.y.)
Science
Science
Nanobodies that neutralize Monoclonal antibodies that bind to the spike protein of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) show therapeutic promise but must be produced in mammalian cells and need to be delivered intravenously. B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11c74ff65944a0933cee2079cf142211
https://pubmed.ncbi.nlm.nih.gov/32817938
https://pubmed.ncbi.nlm.nih.gov/32817938
Autor:
Henry C. Nguyen, Devan Diwanji, Smriti Sangwan, Sayan Gupta, Niv Dobzinski, Michael C. Thompson, M. Zimanyi, Rezelj, Marco Vignuzzi, Camille R. Simoneau, Corie Y. Ralston, Cristina Puchades, Thomas H. Pospiech, Beth S. Zha, Kaihua Zhang, Jiahao Liang, Sergei Pourmal, Axel F. Brilot, David Bulkley, Fei Li, Danielle L. Swaney, Nick Hoppe, A.W. Barile-Hill, Amber M. Smith, Raphael Trenker, Melanie Ott, Un Seng Chio, Gregory E. Merz, Ishan Deshpande, Alexandrea N. Rizo, Peter Walter, Kris M. White, R.A. Saunders, Ming Sun, Aditya A. Anand, Morgane Boone, Adolfo García-Sastre, Cynthia M. Chio, Yanxin Liu, Kaitlin Schaefer, Aashish Manglik, Nevan J. Krogan, Frank R. Moss, S. Dickinson, Huong T. Kratochvil, Caleigh M. Azumaya, Silke Nock, Mingliang Jin, Kristoffer E. Leon, Belyy, Meghna Gupta, Michael Schoof, Christian B. Billesbølle, Bryan Faust, Benjamin Barsi-Rhyne
Publikováno v:
bioRxiv
Without an effective prophylactic solution, infections from SARS-CoV-2 continue to rise worldwide with devastating health and economic costs. SARS-CoV-2 gains entry into host cells via an interaction between its Spike protein and the host cell recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4f1f208dd04d4d89775155b81ed47fe
https://doi.org/10.1101/2020.08.08.238469
https://doi.org/10.1101/2020.08.08.238469
Autor:
Matthieu Masureel, Jean-Baptiste Sibarita, Damien Jullié, Ron O. Dror, Naomi R. Latorraca, Mark von Zastrow, Benjamin Barsi-Rhyne, Kelsie Eichel
Publikováno v:
Nature
β-arrestins are critical regulator and transducer proteins for G-protein-coupled receptors (GPCRs). β-arrestin is widely believed to be activated by forming a stable and stoichiometric GPCR-β-arrestin scaffold complex, which requires and is driven
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2994063a32f220faa6c514d3fb7623aa
http://europepmc.org/articles/PMC6058965
http://europepmc.org/articles/PMC6058965
Autor:
Nebat Ali, Jordan Mitchell, Joy Li, Yanxun V. Yu, Tyler Hill, Martin W. Schneider, Noelle D. L'Etoile, Wagner Steuer Costa, Benjamin Barsi-Rhyne, Chantal Brueggemann, Kristine Andersen, O. Scott Hamilton, Mary Futey, Raakhee Shankar, Aruna Varshney, Jatin Nagpal, Sarah Woldemariam, Miri K. VanHoven, Alan Tran, Denise M. Ferkey, Alexander Gottschalk, Michelle C. Krzyzanowski, Piali Sengupta
Publikováno v:
Genetics, vol 213, iss 1
Genetics
Genetics
cGMP plays a role in sensory signaling and plasticity by regulating ion channels, phosphodiesterases, and kinases. Studies that primarily used genetic and biochemical tools suggest that cGMP is spatiotemporally regulated in multiple sensory modalitie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa92d76a66a4cbae8b8f9aba86626785
https://escholarship.org/uc/item/7zv0d4qn
https://escholarship.org/uc/item/7zv0d4qn
Autor:
Joori Park, Martina Bremer, Benjamin Barsi-Rhyne, Jessica L Jarecki, Anthony B Thomas, Christopher Vargas, Miri K. VanHoven, Kristine M Miller
Publikováno v:
Genetics. 194:175-187
The organization of neurons and the maintenance of that arrangement are critical to brain function. Failure of these processes in humans can lead to severe birth defects, mental retardation, and epilepsy. Several kinesins have been shown to play impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b24d4de22e6ea1bb37bb5340d1e353b
https://doi.org/10.1534/genetics.113.149310
https://doi.org/10.1534/genetics.113.149310