Zobrazeno 1 - 10
of 223
pro vyhledávání: '"Benjamin B. Williams"'
Autor:
Philip E. Schaner, Ly-Binh-An Tran, Bassem I. Zaki, Harold M. Swartz, Eugene Demidenko, Benjamin B. Williams, Alan Siegel, Periannan Kuppusamy, Ann Barry Flood, Bernard Gallez
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
Abstract During a first-in-humans clinical trial investigating electron paramagnetic resonance tumor oximetry, a patient injected with the particulate oxygen sensor Printex ink was found to have unexpected fluorodeoxyglucose (FDG) uptake in a dermal
Externí odkaz:
https://doaj.org/article/64f07c0a11434748a2d9a0bd74b7764a
Autor:
Philip E. Schaner, Benjamin B. Williams, Eunice Y. Chen, Jason R. Pettus, Wilson A. Schreiber, Maciej M. Kmiec, Lesley A. Jarvis, David A. Pastel, Rebecca A. Zuurbier, Roberta M. DiFlorio-Alexander, Joseph A. Paydarfar, Benoit J. Gosselin, Richard J. Barth, Kari M. Rosenkranz, Sergey V. Petryakov, Huagang Hou, Dan Tse, Alexandre Pletnev, Ann Barry Flood, Victoria A. Wood, Kendra A. Hebert, Robyn E. Mosher, Eugene Demidenko, Harold M. Swartz, Periannan Kuppusamy
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
ObjectiveThe overall objective of this clinical study was to validate an implantable oxygen sensor, called the ‘OxyChip’, as a clinically feasible technology that would allow individualized tumor-oxygen assessments in cancer patients prior to and
Externí odkaz:
https://doaj.org/article/2ffb9d447e744139bf8b14916833cd47
Autor:
Philip E. Schaner, Jason R. Pettus, Ann Barry Flood, Benjamin B. Williams, Lesley A. Jarvis, Eunice Y. Chen, David A. Pastel, Rebecca A. Zuurbier, Roberta M. diFlorio-Alexander, Harold M. Swartz, Periannan Kuppusamy
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Introduction: Tumor hypoxia confers both a poor prognosis and increased resistance to oncologic therapies, and therefore, hypoxia modification with reliable oxygen profiling during anticancer treatment is desirable. The OxyChip is an implantable oxyg
Externí odkaz:
https://doaj.org/article/9e88f8dc836d4c73b0b610ee7ca81ed8
Autor:
Muhammad Ramish Ashraf, Mahbubur Rahman, Rongxiao Zhang, Benjamin B. Williams, David J. Gladstone, Brian W. Pogue, Petr Bruza
Publikováno v:
Frontiers in Physics, Vol 8 (2020)
While spatial dose conformity delivered to a target volume has been pushed to its practical limits with advanced treatment planning and delivery, investigations in novel temporal dose delivery are unfolding new mechanisms. Recent advances in ultra-hi
Externí odkaz:
https://doaj.org/article/5d8b3644061d46729adbd35bea39f0ed
Autor:
Harold M. Swartz, Ann Barry Flood, Philip E. Schaner, Howard Halpern, Benjamin B. Williams, Brian W. Pogue, Bernard Gallez, Peter Vaupel
Publikováno v:
Physiological Reports, Vol 8, Iss 15, Pp n/a-n/a (2020)
Abstract It is well understood that the level of molecular oxygen (O2) in tissue is a very important factor impacting both physiology and pathological processes as well as responsiveness to some treatments. Data on O2 in tissue could be effectively u
Externí odkaz:
https://doaj.org/article/6035f9f4fb374398905bf2125f7fe4df
Autor:
Benjamin B. Williams, Niall C. Tebbutt, Michael Buchert, Tracy L. Putoczki, Karen Doggett, Shisan Bao, Cameron N. Johnstone, Frederick Masson, Frederic Hollande, Antony W. Burgess, Andrew M. Scott, Matthias Ernst, Joan K. Heath
Publikováno v:
Disease Models & Mechanisms, Vol 8, Iss 8, Pp 805-815 (2015)
The cells of the intestinal epithelium provide a selectively permeable barrier between the external environment and internal tissues. The integrity of this barrier is maintained by tight junctions, specialised cell-cell contacts that permit the absor
Externí odkaz:
https://doaj.org/article/532a052a19d24f2b9310bf3bc07af194
Reduction of Image Artifacts in Mice by Bladder Flushing with a Novel Double-Lumen Urethral Catheter
Autor:
Chad R. Haney, Adrian D. Parasca, Kazuhiro Ichikawa, Benjamin B. Williams, Martyna Elas, Charles A. Pelizzari, Howard J. Halpern
Publikováno v:
Molecular Imaging, Vol 5 (2006)
In electron paramagnetic resonance imaging (EPRI), the accumulation of contrast agent in the bladder can create a very large source of signal, often far greater than that of the organ of interest. Mouse model images have become increasingly important
Externí odkaz:
https://doaj.org/article/7cd2e4a1c9ae414da389dda91f7f6727
Autor:
Mahbubur Rahman, Rongxiao Zhang, David J. Gladstone, Benjamin B. Williams, Erli Chen, Chad A. Dexter, Lawrence Thompson, Petr Bruza, Brian W. Pogue
Publikováno v:
Practical Radiation Oncology. 13:153-165
Background: Use of a linear accelerator in ultra-high dose rate (UHDR) mode can provide a conduit for wider access to UHDR FLASH effects, sparing normal tissue, but care needs to be taken in the use of such systems to ensure errors are minimized. Pur
PurposeIn our experience treating locally advanced pancreatic cancer (PC) with magnetic resonance-guided radiation therapy (MRgRT), the true-fast imaging with steady-state free precession (TRUFI) sequences used to generate real-time 2D MRI (2D cine)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e87fa0b2612f0b9f6d5e668e138e4c06
https://doi.org/10.1101/2023.04.07.23288201
https://doi.org/10.1101/2023.04.07.23288201
Autor:
Benjamin B. Williams, Periannan Kuppusamy, Sassan Hodge, Kendra A. Hebert, Philip E. Schaner, Dan Tse, Maciej M. Kmiec
Publikováno v:
Magn Reson Med
PURPOSE Electron paramagnetic resonance oximetry using the OxyChip as an implantable oxygen sensor can directly and repeatedly measure tissue oxygen levels. A phase I, first-in-human clinical study has established the safety and feasibility of using