Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Benjamin Arthur Llewellyn Finnin"'
Autor:
S M Wu, David A. Elliott, Benjamin Arthur Llewellyn Finnin, John M. Haynes, David A. Anderson, Ebba Louise Lagerqvist, Colin W. Pouton
Publikováno v:
Journal of Pharmacological and Toxicological Methods. 74:17-25
Pluripotent stem cells offer an unparalleled opportunity to investigate cardiac physiology, pharmacology, toxicology and pathophysiology. In this paper we describe the use of both mouse (Nkx2-5(eGFP/w)) and human (NKX2-5(eGFP/w)) pluripotent stem cel
Autor:
Elizabeth D. Williams, Linda J. Chan, David J. Owen, Gemma Ryan, Lisa M. Kaminskas, Natalie L. Trevaskis, Christopher J.H. Porter, David B. Ascher, Erica K. Sloan, Brian Kelly, Benjamin Arthur Llewellyn Finnin, Seth Adam Jones, Tony Velkov, John M. Haynes, Mark Williamson, Victoria M. McLeod
Publikováno v:
Molecular Pharmaceutics. 12:432-443
The current study sought to explore whether the subcutaneous administration of lymph targeted dendrimers, conjugated with a model chemotherapeutic (methotrexate, MTX), was able to enhance anticancer activity against lymph node metastases. The lymphat
Autor:
Benjamin Arthur Llewellyn Finnin, Jonnathan Hadgraft, Simon Gaisford, Michael A. A. O'Neill, Anthony E. Beezer, Patrick Sears
Publikováno v:
Journal of Thermal Analysis and Calorimetry. 83:331-334
Isothermal calorimetry is becoming indispensable as a tool for the study of a wide variety of systems. As with all scientific instruments it is essential that robust calibration routines be developed in order to validate the data obtained. Chemical t
Autor:
John M. Haynes, Brigham J. Hartley, Stewart A. Fabb, Colin W. Pouton, Benjamin Arthur Llewellyn Finnin
Publikováno v:
Journal of Visualized Experiments.
One major limitation with current human embryonic stem cell (ESC) differentiation protocols is the generation of heterogeneous cell populations. These cultures contain the cells of interest, but are also contaminated with undifferentiated ESCs, non-n
Autor:
Prudence A. Hill, Jian Li, Kathryn Erin Davis, Tony Velkov, Anima Poudyal, Jinhua Li, Mohammad Abul Kalam Azad, Roger L. Nation, Benjamin Arthur Llewellyn Finnin
The nephrotoxicity of polymyxins is a major dose-limiting factor for treatment of infections caused by multidrug-resistant Gram-negative pathogens. The mechanism(s) of polymyxin-induced nephrotoxicity is not clear. This study aimed to investigate pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfec3b97bb4b0a416dfa682b0dfd89f
https://europepmc.org/articles/PMC3754291/
https://europepmc.org/articles/PMC3754291/
Autor:
David M. Shackleford, Andreas Moeller, Matthew A. Pimentel, Sarah J. Creed, Izhak Haviv, Caroline P. Le, Ming Gene Chai, Erica K. Sloan, J. Robert Lane, Benjamin Arthur Llewellyn Finnin
Publikováno v:
Molecular Cancer Research. 11:B092-B092
Chronic stress accelerates breast cancer metastasis through beta-adrenergic signaling and recent clinical studies found that beta-blockade reduced metastasis in women with breast cancer. However, the specific beta-adrenergic receptor subtype(s) throu
Publikováno v:
Stem Cell Research. (1):23-33
Embryonic stem cell-derived cardiomyocytes (ESC-CMs) have applications in understanding cardiac disease pathophysiology, pharmacology, and toxicology. Comprehensive characterization of their basic physiological and pharmacological properties is criti