Výsledky vyhledávání - "Benjamin Abell"

Akademický článek

Analysis of Toxic Amyloid Fibril Interactions at Natively Derived Membranes by Ellipsometry.

Autor: Rachel A S Smith, Aleksey Nabok, Ben J F Blakeman, Wei-Feng Xue, Benjamin Abell, David P Smith

Publikováno v: PLoS ONE, Vol 10, Iss 7, p e0132309 (2015)

There is an ongoing debate regarding the culprits of cytotoxicity associated with amyloid disorders. Although small pre-fibrillar amyloid oligomers have been implicated as the primary toxic species, the fibrillar amyloid material itself can also indu

Externí odkaz: https://doaj.org/article/277f0b6032ea475b8f65316ac324d9fe

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Akademický článek

Influence of Cooling duration on Efficacy in Cardiac Arrest Patients (ICECAP): study protocol for a multicenter, randomized, adaptive allocation clinical trial to identify the optimal duration of induced hypothermia for neuroprotection in comatose, adult survivors of after out-of-hospital cardiac arrest

Autor: William J. Meurer, Florian F. Schmitzberger, Sharon Yeatts, Viswanathan Ramakrishnan, Benjamin Abella, Tom Aufderheide, William Barsan, Justin Benoit, Scott Berry, Joy Black, Nia Bozeman, Kristine Broglio, Jeremy Brown, Kimberly Brown, Noelle Carlozzi, Angela Caveney, Sung-Min Cho, Hangyul Chung-Esaki, Robert Clevenger, Robin Conwit, Richelle Cooper, Valentina Crudo, Mohamud Daya, Deneil Harney, Cindy Hsu, Nicholas J. Johnson, Imad Khan, Shaveta Khosla, Peyton Kline, Anna Kratz, Peter Kudenchuk, Roger J. Lewis, Chaitra Madiyal, Sara Meyer, Jarrod Mosier, Marwan Mouammar, Matthew Neth, Brian O’Neil, James Paxton, Sofia Perez, Sarah Perman, Cemal Sozener, Mickie Speers, Aimee Spiteri, Valerie Stevenson, Kavita Sunthankar, Joseph Tonna, Scott Youngquist, Romergryko Geocadin, Robert Silbergleit, ICECAP trial investigators

Publikováno v: Trials, Vol 25, Iss 1, Pp 1-23 (2024)

Abstract Background Cardiac arrest is a common and devastating emergency of both the heart and brain. More than 380,000 patients suffer out-of-hospital cardiac arrest annually in the USA. Induced cooling of comatose patients markedly improved neurolo

Externí odkaz: https://doaj.org/article/d175c8409ccf45f19bb469ca803b04d6

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Mutational analysis of the alpha subunit of eIF2B provides insights into the role of eIF2B bodies in translational control and VWM disease

Autor: Tawni Dornelles, Rachel E Hodgson, Mark P. Ashe, Susan G. Campbell, Benjamin Abell, Karl Norris, K Elizabeth Allen

Publikováno v: The Journal of Biological Chemistry
Norris, K, Hodgson, R E, Dornelles, T, Allen, K E, Abell, B M, Ashe, M P & Campbell, S G 2020, ' Mutational analysis of the alpha subunit of eIF2B provides insights into the role of eIF2B bodies in translational control and VWM disease ', The Journal of biological chemistry . https://doi.org/10.1074/jbc.RA120.014956

Eukaryotic initiation factor 2B (eIF2B) serves as a vital control point within protein synthesis and regulates translation initiation in response to cellular stress. Mutations within eIF2B result in the fatal disease, leukoencephalopathy with vanishi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48bbe2734e8e96bd8429c56aebca073a
http://europepmc.org/articles/PMC7948505

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Alternative splicing of the auxin biosynthesis gene YUCCA4 determines its subcellular compartmentation

Autor: Verena Kriechbaumer, Pengwei Wang, Chris Hawes, Benjamin Abell

Publikováno v: The Plant Journal. 70:292-302

Auxin is a major growth hormone in plants, and recent studies have elucidated many of the molecular mechanisms underlying its action, including transport, perception and signal transduction. However, major gaps remain in our knowledge of auxin biosyn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2496bf9c0bb0ca8745a59b952f960b98
https://doi.org/10.1111/j.1365-313x.2011.04866.x

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Study of Receptor-Chaperone Interactions Using the Optical Technique of Spectroscopic Ellipsometry

Autor: David Smith, Mohd Kamarulzaki Mustafa, Alexei Nabok, Joanne Lacey, A. Tsargorodskaya, Tatiana M. Vinogradova, Benjamin Abell, Verena Kriechbaumer

Publikováno v: Biophysical Journal. 101:504-511

This work describes a detailed quantitative interaction study between the novel plastidial chaperone receptor OEP61 and isoforms of the chaperone types Hsp70 and Hsp90 using the optical method of total internal reflection ellipsometry (TIRE). The rec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7948a8ee1e4225ef14edd15e3e94d326
https://doi.org/10.1016/j.bpj.2011.06.011

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Chaperone receptors: guiding proteins to intracellular compartments

Autor: Ottillie von Loffelholz, Verena Kriechbaumer, Benjamin Abell

Publikováno v: Protoplasma. 249:21-30

Despite mitochondria and chloroplasts having their own genome, 99% of mitochondrial proteins (Rehling et al., Nat Rev Mol Cell Biol 5:519-530, 2004) and more than 95% of chloroplast proteins (Soll, Curr Opin Plant Biol 5:529-535, 2002) are encoded by

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fcc78e7b3a3bdfa9ca571f74b82a56f
https://doi.org/10.1007/s00709-011-0270-9

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Subcellular Distribution of Tail-Anchored Proteins in Arabidopsis

Autor: Verena Kriechbaumer, Rowena Shaw, Benjamin Abell, Anne-Marie Harrison, Caroline G. Bowsher, Joy Mukherjee

Publikováno v: Traffic. 10:1753-1764

Tail-anchored (TA) proteins function in key cellular processes in eukaryotic cells, such as vesicle trafficking, protein translocation and regulation of transcription. They anchor to internal cell membranes by a C-terminal transmembrane domain, which

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::075ab3c63e999004cd6cd421706346fa
https://doi.org/10.1111/j.1600-0854.2009.00991.x

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Post-translational integration of tail-anchored proteins is facilitated by defined molecular chaperones

Autor: Jason C. Young, Catherine Rabu, Benjamin Abell, Pawel Leznicki, Stephen High

Publikováno v: Journal of Cell Science. 120:1743-1751

Tail-anchored (TA) proteins provide an ideal model for studying post-translational integration at the endoplasmic reticulum (ER) of eukaryotes. There are multiple pathways for delivering TA proteins from the cytosol to the ER membrane yet, whereas an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f19ceeda297caf6127c616910f21f26f
https://doi.org/10.1242/jcs.002410

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Reciprocity and resilience: teaching and learning sustainable social enterprise through gaming

Autor: Rory Ridley-Duff, Arun Sukumar, Stephen Dobson, Chris Roast, Benjamin Abell

Against a backdrop of increased global environmental and economic uncertainty, the resilience and sustainability of urban communities is a paramount concern for decision makers. The work presented here aims to explore how teaching and learning around

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce2b5534a7f0bfad5aa3efdedf41ff25
https://shura.shu.ac.uk/9693/1/Dobson_-_reciprocity_and_resilience_-_JOTSC_submission-accepted_version.pdf

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Tail-anchored protein biosynthesis at the endoplasmic reticulum: the same but different

Autor: Benjamin Abell, Stephen High

Publikováno v: Biochemical Society Transactions. 32:659-662

The post-translational integration of tail-anchored proteins at the endoplasmic reticulum represents a novel and distinct pathway for membrane protein synthesis. Studies of various precursors, exemplified by the synaptobrevins and cytochrome b5, indi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f53c5734286f18738c35812afc36c7d4
https://doi.org/10.1042/bst0320659

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