Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Benjamin A. Shoemaker"'
Autor:
Anna R. Panchenko, Stanley Lipkowitz, Andrew L. Cangelosi, Juan Crespo-Barreto, Benjamin A. Shoemaker, Ke Ma, Stephen C. Kales, Minghui Li
Fig. S1. The distribution of unfolding and binding free energy changes for Single, Recurrent and Random class mutations for all states in CBL activation cycle. Fig.S2. The distribution of local RMSD of mutant structures for Single, Recurrent and Rand
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb546c494c2f73006222586e7feb390
https://doi.org/10.1158/0008-5472.22409519.v1
https://doi.org/10.1158/0008-5472.22409519.v1
Autor:
Anna R. Panchenko, Stanley Lipkowitz, Andrew L. Cangelosi, Juan Crespo-Barreto, Benjamin A. Shoemaker, Ke Ma, Stephen C. Kales, Minghui Li
Detailed description of methods for computational modeling and analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ca8c934d75e8eafa86e7076d2ad1688
https://doi.org/10.1158/0008-5472.22409516.v1
https://doi.org/10.1158/0008-5472.22409516.v1
Autor:
Anna R. Panchenko, Stanley Lipkowitz, Andrew L. Cangelosi, Juan Crespo-Barreto, Benjamin A. Shoemaker, Ke Ma, Stephen C. Kales, Minghui Li
Oncogenic mutations in the monomeric Casitas B-lineage lymphoma (Cbl) gene have been found in many tumors, but their significance remains largely unknown. Several human c-Cbl (CBL) structures have recently been solved, depicting the protein at differ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34514988a1daef25bcffcf099d6e7902
https://doi.org/10.1158/0008-5472.c.6507806
https://doi.org/10.1158/0008-5472.c.6507806
Autor:
Sunghwan Kim, Jie Chen, Tiejun Cheng, Asta Gindulyte, Jia He, Siqian He, Qingliang Li, Benjamin A Shoemaker, Paul A Thiessen, Bo Yu, Leonid Zaslavsky, Jian Zhang, Evan E Bolton
Publikováno v:
Nucleic Acids Res
PubChem (https://pubchem.ncbi.nlm.nih.gov) is a popular chemical information resource that serves a wide range of use cases. In the past two years, a number of changes were made to PubChem. Data from more than 120 data sources was added to PubChem. S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4be0bc8b5bdc9909279d5f856d6dec80
https://europepmc.org/articles/PMC9825602/
https://europepmc.org/articles/PMC9825602/
Autor:
Pierrick, Wainschtein, Deepti, Jain, Zhili, Zheng, L Adrienne, Cupples, Aladdin H, Shadyab, Barbara, McKnight, Benjamin M, Shoemaker, Braxton D, Mitchell, Bruce M, Psaty, Charles, Kooperberg, Ching-Ti, Liu, Christine M, Albert, Dan, Roden, Daniel I, Chasman, Dawood, Darbar, Donald M, Lloyd-Jones, Donna K, Arnett, Elizabeth A, Regan, Eric, Boerwinkle, Jerome I, Rotter, Jeffrey R, O'Connell, Lisa R, Yanek, Mariza, de Andrade, Matthew A, Allison, Merry-Lynn N, McDonald, Mina K, Chung, Myriam, Fornage, Nathalie, Chami, Nicholas L, Smith, Patrick T, Ellinor, Ramachandran S, Vasan, Rasika A, Mathias, Ruth J F, Loos, Stephen S, Rich, Steven A, Lubitz, Susan R, Heckbert, Susan, Redline, Xiuqing, Guo, Y -D Ida, Chen, Cecelia A, Laurie, Ryan D, Hernandez, Stephen T, McGarvey, Michael E, Goddard, Cathy C, Laurie, Kari E, North, Leslie A, Lange, Bruce S, Weir, Loic, Yengo, Jian, Yang, Michael, Zody
Publikováno v:
Nature genetics. 54(3)
Analyses of data from genome-wide association studies on unrelated individuals have shown that, for human traits and diseases, approximately one-third to two-thirds of heritability is captured by common SNPs. However, it is not known whether the rema
Autor:
Paul A. Thiessen, Sunghwan Kim, Jia He, Leonid Zaslavsky, Qingliang Li, Bo Yu, Tiejun Cheng, Evan E Bolton, Benjamin A. Shoemaker, Asta Gindulyte, Jian Zhang, Siqian He, Jie Chen
Publikováno v:
Nucleic Acids Research
PubChem (https://pubchem.ncbi.nlm.nih.gov) is a key chemical information resource for the biomedical research community. Substantial improvements were made in the past few years. New data content was added, including spectral information, scientific
Autor:
Hafumi Nishi, Manoj Tyagi, Shaolei Teng, Benjamin A Shoemaker, Kosuke Hashimoto, Emil Alexov, Stefan Wuchty, Anna R Panchenko
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e66273 (2013)
Many studies have shown that missense mutations might play an important role in carcinogenesis. However, the extent to which cancer mutations might affect biomolecular interactions remains unclear. Here, we map glioblastoma missense mutations on the
Externí odkaz:
https://doaj.org/article/cc59b712e66c4835861880e5ec4022ae
Autor:
Jessica H Fong, Benjamin A Shoemaker, Sergiy O Garbuzynskiy, Michail Y Lobanov, Oxana V Galzitskaya, Anna R Panchenko
Publikováno v:
PLoS Computational Biology, Vol 5, Iss 3, p e1000316 (2009)
We perform a large-scale study of intrinsically disordered regions in proteins and protein complexes using a non-redundant set of hundreds of different protein complexes. In accordance with the conventional view that folding and binding are coupled,
Externí odkaz:
https://doaj.org/article/fae7624c2cf143aab5955ba489bf4a81
Autor:
Benjamin A Shoemaker, Anna R Panchenko
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 4, p e43 (2007)
Recent advances in high-throughput experimental methods for the identification of protein interactions have resulted in a large amount of diverse data that are somewhat incomplete and contradictory. As valuable as they are, such experimental approach
Externí odkaz:
https://doaj.org/article/8932c54860e5426a914a57f6abdb4507
Autor:
Benjamin A Shoemaker, Anna R Panchenko
Publikováno v:
PLoS Computational Biology, Vol 3, Iss 3, p e42 (2007)
Externí odkaz:
https://doaj.org/article/b1cb670082f84726939ce03010b3de56