Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Benjamin A. Levinson"'
Publikováno v:
Melanoma research. 32(5)
Checkpoint immunotherapies (CPIs) have improved outcomes for metastatic melanoma patients, with objective response rates to combination ipilimumab and nivolumab of ~58%. Preclinical data suggest that histone deacetylase (HDAC) inhibition enhances ant
Autor:
A Samer Al-Homsi, Frank Cirrone, Stephanie Wo, Kelli Cole, J Andres Suarez-Londono, Sharon L Gardner, Jingmei Hsu, Kelsey Stocker, Benedetto Bruno, Judith D. Goldberg, Benjamin A Levinson, Maher Abdul-Hay
Publikováno v:
Blood Advances.
Reducing the incidence of graft-versus host disease (GvHD) following haploidentical hematopoietic stem cell transplantation (HSCT) is warranted. Post-transplant cyclophosphamide (PTCy) is the main agent used for GvHD prevention in this setting. It re
Autor:
Benjamin T Levinson, Kristen H. Taylor, Almamun, Olha Kholod, J. Wade Davis, Gerald L Arthur, Alexei J. Stuckel, Nathan T. Johnson
Publikováno v:
Leukemia & Lymphoma. 58:2156-2164
A complete understanding of the mechanisms involved in the development of pre-B ALL is lacking. In this study, we integrated DNA methylation data and gene expression data to elucidate the impact of aberrant intergenic DNA methylation on gene expressi
Autor:
Gerald L Arthur, Benjamin T Levinson, Almamun, Stephanie D. McKay, Kristen H. Taylor, Nathan T. Johnson, J. Wade Davis, Annette C van Swaay
Publikováno v:
Epigenetics
Acute lymphoblastic leukemia (ALL) is the most common cancer diagnosed in children under the age of 15. In addition to genetic aberrations, epigenetic modifications such as DNA methylation are altered in cancer and impact gene expression. To identify
Autor:
Benjamin T Levinson, Kristen H. Taylor, Robert D. Schnabel, Susan T. Gater, Almamun, Gerald L Arthur, J. Wade Davis
Publikováno v:
Epigenetics
DNA methylation is responsible for regulating gene expression and cellular differentiation and for maintaining genomic stability during normal human development. Furthermore, it plays a significant role in the regulation of hematopoiesis. In order to
Autor:
Lihua Wang, Kaare Christensen, Shiow J. Lin, Qunyuan Zhang, E. Warwick Daw, Joseph H. Lee, Benjamin T. Levinson, Michael A. Province, Anne B. Newman, Richard Mayeux, Bharat Thyagarajan, Enrique Ramos, Haley J. Abel, Sara E. Chasnoff, Todd E. Druley
Publikováno v:
Druley, T E, Wang, L, Lin, S J, Lee, J H, Zhang, Q, Daw, E W, Abel, H J, Chasnoff, S E, Ramos, E I, Levinson, B T, Thyagarajan, B, Newman, A B, Christensen, K, Mayeux, R & Province, M A 2016, ' Candidate gene resequencing to identify rare, pedigree-specific variants influencing healthy aging phenotypes in the long life family study ', BMC Geriatrics, vol. 16, no. 1, 80, pp. 1-12 . https://doi.org/10.1186/s12877-016-0253-y
BMC Geriatrics
BMC Geriatrics
BACKGROUND: The Long Life Family Study (LLFS) is an international study to identify the genetic components of various healthy aging phenotypes. We hypothesized that pedigree-specific rare variants at longevity-associated genes could have a similar fu
Autor:
Iulia Giuroiu, Geoffrey Yuyat Ku, Lawrence P. Leichman, Kevin Lee Du, Philmo Oh, Benjamin A. Levinson, Syma Iqbal, Charles R. Thomas, Jennifer J. Wu
Publikováno v:
Journal of Clinical Oncology. 36:TPS199-TPS199
TPS199 Background: ESCC comprises 80% of esophageal cancers worldwide. Preoperative chemoRT is a standard-of-care based on the CROSS trial ( N Engl J Med 2012;366:2074-2084), which reported encouraging pathologic complete response (pCR) and overall s
We detected flavins in the growth medium of the methanotrophic bacterium Methylocystis species strain M. Flavin secretion correlates with growth stage and increases under iron starvation conditions. Two other methanotrophs, Methylosinus trichosporium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b84b75623a5454e906e9007997ebc4ec
https://europepmc.org/articles/PMC2976244/
https://europepmc.org/articles/PMC2976244/
Autor:
Katherine C. Thornton, Margaret W. Leigh, Emily H. Turner, Benjamin T. Levinson, Deborah A. Nickerson, Maimoona A. Zariwala, Laura G. Van Arendonk, Amjad Horani, Philip V. Bayly, Kate S. Wilson, Susan K. Dutcher, Joseph C. Giacalone, Alison J. Albee, Todd E. Druley, Steven L. Brody, Thomas Ferkol, Michael R. Knowles, Anand C. Patel, Jay Shendure
Publikováno v:
The American Journal of Human Genetics. (4):685-693
Motile cilia are essential components of the mucociliary escalator and are central to respiratory-tract host defenses. Abnormalities in these evolutionarily conserved organelles cause primary ciliary dyskinesia (PCD). Despite recent strides character
Autor:
Michael A. Province, Allie Y. Li, Andrew L. Young, Katherine C. Thornton, Benjamin T. Levinson, Todd E. Druley, Andrew E. O. Hughes, Enrique Ramos, Francesco Vallania, Sara E. Chasnoff
Publikováno v:
Europe PubMed Central
BMC Genomics, Vol 13, Iss 1, p 683 (2012)
BMC Genomics
BMC Genomics, Vol 13, Iss 1, p 683 (2012)
BMC Genomics
Background Rare genetic variation in the human population is a major source of pathophysiological variability and has been implicated in a host of complex phenotypes and diseases. Finding disease-related genes harboring disparate functional rare vari