Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Benjamin A Juliar"'
Autor:
Louisa Helms, Silvia Marchiano, Ian B. Stanaway, Tien-Ying Hsiang, Benjamin A. Juliar, Shally Saini, Yan Ting Zhao, Akshita Khanna, Rajasree Menon, Fadhl Alakwaa, Carmen Mikacenic, Eric D. Morrell, Mark M. Wurfel, Matthias Kretzler, Jennifer L. Harder, Charles E. Murry, Jonathan Himmelfarb, Hannele Ruohola-Baker, Pavan K. Bhatraju, Michael Gale Jr., Benjamin S. Freedman
Publikováno v:
JCI Insight, Vol 6, Iss 24 (2021)
Kidneys are critical target organs of COVID-19, but susceptibility and responses to infection remain poorly understood. Here, we combine SARS-CoV-2 variants with genome-edited kidney organoids and clinical data to investigate tropism, mechanism, and
Externí odkaz:
https://doaj.org/article/f1245ff7051b4c249e2410817e4f3c9e
Autor:
Eric D. Morrell, Pavan K. Bhatraju, Matthias Kretzler, Fadhl M. Al-Akwaa, Shally Saini, Hannele Ruohola-Baker, Louisa Helms, Benjamin S. Freedman, Rajasree Menon, Mark M. Wurfel, Silvia Marchianò, Michael Gale, Yan Ting Zhao, Benjamin A Juliar, Jonathan Himmelfarb, Carmen Mikacenic, Akshita Khanna, Tien-Ying Hsiang, Ian B. Stanaway, Charles E. Murry, Jennifer L. Harder
Publikováno v:
JCI Insight
Kidneys are critical target organs of COVID-19, but susceptibility and responses to infection remain poorly understood. Here, we combine SARS-CoV-2 variants with genome edited kidney organoids and clinical data to investigate tropism, mechanism, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c566f08c9e57bc163caff2d5dfd7bb5a
https://doi.org/10.1172/jci.insight.154882
https://doi.org/10.1172/jci.insight.154882
Autor:
Jeffrey A. Beamish, Andrew J. Putnam, David S. Cleveland, Likitha Nimmagadda, Benjamin A. Juliar, Megan E. Busch
Publikováno v:
J Biomed Mater Res B Appl Biomater
Extracellular matrix (ECM) remodeling is essential for the process of capillary morphogenesis. Here we employed synthetic poly(ethylene glycol) (PEG) hydrogels engineered with proteolytic specificity to either matrix metalloproteinases (MMPs), plasmi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c9dd935b5c628c78fe65e29fa8cda2c
https://doi.org/10.1002/jbm.b.34341
https://doi.org/10.1002/jbm.b.34341
Publikováno v:
Biotechnology and Bioengineering. 116:415-426
Forming functional blood vessel networks is a major clinical challenge in the fields of tissue engineering and therapeutic angiogenesis. Cell-based strategies to promote neovascularization have been widely explored, but cell sourcing remains a signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::861f24b6e20b8197acdc632d603825de
https://doi.org/10.1002/bit.26860
https://doi.org/10.1002/bit.26860
Autor:
Andrew J. Putnam, Carey N. Lumeng, Clarissa Strieder-Barboza, Monita Karmakar, Nicki A. Baker, Oliver A. Varban, Robert W. O'Rourke, Benjamin A. Juliar, Carmen G. Flesher
Publikováno v:
Biorheology
Background Obesity-induced chronic inflammation and fibrosis in adipose tissue contributes to the progression of type 2 diabetes mellitus (DM). While fibrosis is known to induce mechanical stiffening of numerous tissue types, it is unknown whether DM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac1d1b2bb92d924144f1404aab8cf58e
https://europepmc.org/articles/PMC7876417/
https://europepmc.org/articles/PMC7876417/
Autor:
Andrew J. Putnam, Kailee Kingston, Benjamin A. Juliar, Xiaoxiao Dong, Mario L. Fabiilli, Emily Brewer, Renny T. Franceschi, Xiaofang Lu, J. Brian Fowlkes, Oliver D. Kripfgans, Zheng Liu
Publikováno v:
Acta Biomater
The challenge of translating pro-angiogenic growth factors for therapeutic purposes has stimulated a myriad of biomaterials-based, delivery approaches. Many techniques rely on incorporating a growth factor into a hydrogel. The kinetics of release can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::91a44f8752b3519e9a5cfe0f381802c0
https://pubmed.ncbi.nlm.nih.gov/31404713
https://pubmed.ncbi.nlm.nih.gov/31404713
Autor:
Andrew J. Putnam, Jan P. Stegemann, Cheri X. Deng, Weiping Li, Benjamin A. Juliar, Eric C. Hobson
Publikováno v:
Biomaterials
Resonant Acoustic Rheometry (RAR) is a new, non-contact technique to characterize the mechanical properties of soft and viscoelastic biomaterials, such as hydrogels, that are used to mimic the extracellular matrix in tissue engineering. RAR uses a fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab295fc0bf7b30000861929d393aa03e
https://doi.org/10.1016/j.biomaterials.2021.120676
https://doi.org/10.1016/j.biomaterials.2021.120676
Autor:
Megan E. Busch, Likitha Nimmagadda, Andrew J. Putnam, David S. Cleveland, Jeffrey A. Beamish, Benjamin A. Juliar
Publikováno v:
Biomaterials
There is a critical need for biomaterials that support robust neovascularization for a wide-range of clinical applications. Here we report how cells alter tissue-level mechanical properties during capillary morphogenesis using a model of endothelial-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecac09cf9342ba328a8d7430bf395a8f
https://doi.org/10.1016/j.biomaterials.2019.119634
https://doi.org/10.1016/j.biomaterials.2019.119634
Non-adhesive alginate hydrogels support growth of pluripotent stem cell-derived intestinal organoids
Autor:
Meghan M. Capeling, Andrew J. Putnam, Benjamin A. Juliar, Angeline Wu, Yang Song, Yu-Hwai Tsai, Shuichi Takayama, Melinda S. Nagy, Michael A. Helmrath, Nambirajan Sundaram, Jason R. Spence, Michael Czerwinski, Eben Alsberg, Sha Huang
SummaryHuman intestinal organoids (HIOs) represent a powerful system to study human development and are promising candidates for clinical translation as drug-screening tools or engineered tissue. Experimental control and clinical use of HIOs is limit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::515c0b3257cb28190ac3d7ce48594c4b
https://doi.org/10.1101/364885
https://doi.org/10.1101/364885
Autor:
Shuichi Takayama, Andrés J. García, Andrew J. Putnam, Melinda S. Nagy, Meghan M. Capeling, Eben Alsberg, Michael Czerwinski, Yu-Hwai Tsai, Michael A. Helmrath, Yang Song, Angeline Wu, Benjamin A. Juliar, Nambirajan Sundaram, Jason R. Spence, Woojin M. Han, Sha Huang
Publikováno v:
Stem Cell Reports
Stem Cell Reports, Vol 12, Iss 2, Pp 381-394 (2019)
Stem Cell Reports, Vol 12, Iss 2, Pp 381-394 (2019)
Summary Human intestinal organoids (HIOs) represent a powerful system to study human development and are promising candidates for clinical translation as drug-screening tools or engineered tissue. Experimental control and clinical use of HIOs is limi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b76fa6cf2999257da35c719cf31ffa08
https://pubmed.ncbi.nlm.nih.gov/30612954
https://pubmed.ncbi.nlm.nih.gov/30612954