Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Benjamin, Tang"'
Autor:
Chin Wee Tan, Jinjin Chen, Ning Liu, Dharmesh D. Bhuva, Tony Blick, James Monkman, Caroline Cooper, Malvika Kharbanda, Kristen Feher, Belinda Phipson, Emily E. Killingbeck, Liuliu Pan, Youngmi Kim, Yan Liang, Andy Nam, Michael Leon, Paulo Souza-Fonseca-Guimaraes, Seigo Nagashima, Ana Paula Camargo Martins, Cleber Machado-Souza, Lucia de Noronha, Benjamin Tang, Kirsty Short, John Fraser, Gabrielle T. Belz, Fernando Souza-Fonseca-Guimaraes, Arutha Kulasinghe, Melissa J. Davis
Publikováno v:
EBioMedicine, Vol 101, Iss , Pp 105016- (2024)
Summary: The utilization of single-cell resolved spatial transcriptomics to delineate immune responses during SARS-CoV-2 infection was able to identify M1 macrophages to have elevated expression of IFI27 in areas of infection.
Externí odkaz:
https://doaj.org/article/4f2fdb2f06f84144987d21c5de056820
Autor:
Ljubomir Buturovic, Hong Zheng, Benjamin Tang, Kevin Lai, Win Sen Kuan, Mark Gillett, Rahul Santram, Maryam Shojaei, Raquel Almansa, Jose Ángel Nieto, Sonsoles Muñoz, Carmen Herrero, Nikolaos Antonakos, Panayiotis Koufargyris, Marina Kontogiorgi, Georgia Damoraki, Oliver Liesenfeld, James Wacker, Uros Midic, Roland Luethy, David Rawling, Melissa Remmel, Sabrina Coyle, Yiran E. Liu, Aditya M. Rao, Denis Dermadi, Jiaying Toh, Lara Murphy Jones, Michele Donato, Purvesh Khatri, Evangelos J. Giamarellos-Bourboulis, Timothy E. Sweeney
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Predicting the severity of COVID-19 remains an unmet medical need. Our objective was to develop a blood-based host-gene-expression classifier for the severity of viral infections and validate it in independent data, including COVID-19. We de
Externí odkaz:
https://doaj.org/article/ee4e353ebc1a4a9cbf2de80046f1b3f4
Autor:
Ya Wang, Klaus Schughart, Tiana Maria Pelaia, Tracy Chew, Karan Kim, Thomas Karvunidis, Ben Knippenberg, Sally Teoh, Amy L. Phu, Kirsty R. Short, Jonathan Iredell, Irani Thevarajan, Jennifer Audsley, Stephen Macdonald, Jonathon Burcham, Anthony McLean, PREDICT-19 consortium, Benjamin Tang, Maryam Shojaei, Alberto Ballestrero, Allan Cripps, Amanda Cox, Amy L Phu, Andrea De Maria, Arutha Kulasinghe, Ben Marais, Carl Feng, Damien Chaussabel, Darawan Rinchai, Davide Bedognetti, Gabriele Zoppoli, Gunawan Gunawan, John-Sebastian Eden, Kirsty Renfree Short, Mandira Chakraborty, Marcela Kralovcova, Marek Nalos, Marko Radic, Martin Matejovic, Meagan Carney, Michele Bedognetti, Miroslav Prucha, Mohammed Toufiq, Nandan Deshpande, Narasaraju Teluguakula, Nicholas West, Paolo Cremonesi, Philip Britton, Ricardo Garcia Branco, Rodolphe Thiebaut, Rostyslav Bilyy, Stephen MacDonald, Tania Sorrell, Tim Kwan, Tri Giang Phan, Velma Herwanto, Win Sen Kuan, Yoann Zerbib
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
BackgroundCoronavirus disease 2019 (COVID-19) is an infectious disease caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Infected individuals display a wide spectrum of disease severity, as defined by the World Health Organizati
Externí odkaz:
https://doaj.org/article/c8638ac3ce2242629135c4263dfa545d
Autor:
Maryam Shojaei, Amir Shamshirian, James Monkman, Laura Grice, Minh Tran, Chin Wee Tan, Siok Min Teo, Gustavo Rodrigues Rossi, Timothy R. McCulloch, Marek Nalos, Maedeh Raei, Alireza Razavi, Roya Ghasemian, Mobina Gheibi, Fatemeh Roozbeh, Peter D. Sly, Kirsten M. Spann, Keng Yih Chew, Yanshan Zhu, Yao Xia, Timothy J. Wells, Alexandra Cristina Senegaglia, Carmen Lúcia Kuniyoshi, Claudio Luciano Franck, Anna Flavia Ribeiro dos Santos, Lucia de Noronha, Sepideh Motamen, Reza Valadan, Omolbanin Amjadi, Rajan Gogna, Esha Madan, Reza Alizadeh-Navaei, Liliana Lamperti, Felipe Zuñiga, Estefania Nova-Lamperti, Gonzalo Labarca, Ben Knippenberg, Velma Herwanto, Ya Wang, Amy Phu, Tracy Chew, Timothy Kwan, Karan Kim, Sally Teoh, Tiana M. Pelaia, Win Sen Kuan, Yvette Jee, Jon Iredell, Ken O’Byrne, John F. Fraser, Melissa J. Davis, Gabrielle T. Belz, Majid E. Warkiani, Carlos Salomon Gallo, Fernando Souza-Fonseca-Guimaraes, Quan Nguyen, Anthony Mclean, Arutha Kulasinghe, Kirsty R. Short, Benjamin Tang
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
PurposeRobust biomarkers that predict disease outcomes amongst COVID-19 patients are necessary for both patient triage and resource prioritisation. Numerous candidate biomarkers have been proposed for COVID-19. However, at present, there is no consen
Externí odkaz:
https://doaj.org/article/90cb309064c14456837451531198b0a2
Autor:
Michail Yekelchyk, Esha Madan, Jochen Wilhelm, Kirsty R Short, António M Palma, Linbu Liao, Denise Camacho, Everlyne Nkadori, Michael T Winters, Emily S Rice, Inês Rolim, Raquel Cruz‐Duarte, Christopher J Pelham, Masaki Nagane, Kartik Gupta, Sahil Chaudhary, Thomas Braun, Raghavendra Pillappa, Mark S Parker, Thomas Menter, Matthias Matter, Jasmin Dionne Haslbauer, Markus Tolnay, Kornelia D Galior, Kristina A Matkwoskyj, Stephanie M McGregor, Laura K Muller, Emad A Rakha, Antonio Lopez‐Beltran, Ronny Drapkin, Maximilian Ackermann, Paul B Fisher, Steven R Grossman, Andrew K Godwin, Arutha Kulasinghe, Ivan Martinez, Clay B Marsh, Benjamin Tang, Max S Wicha, Kyoung Jae Won, Alexandar Tzankov, Eduardo Moreno, Rajan Gogna
Publikováno v:
EMBO Molecular Medicine, Vol 13, Iss 11, Pp 1-17 (2021)
Abstract Risk stratification of COVID‐19 patients is essential for pandemic management. Changes in the cell fitness marker, hFwe‐Lose, can precede the host immune response to infection, potentially making such a biomarker an earlier triage tool.
Externí odkaz:
https://doaj.org/article/f8eb078fb27a469bb4350f69d131fd6a
Publikováno v:
Applied Sciences, Vol 13, Iss 13, p 7639 (2023)
The Medical Device Regulation (MDR) in Europe aims to improve patient safety by increasing requirements, particularly for the clinical evaluation of medical devices. Before the clinical evaluation is initiated, a first literature review of existing c
Externí odkaz:
https://doaj.org/article/99e90607ae00436383ee7903918d1846
Autor:
Darawan Rinchai, Basirudeen Syed Ahamed Kabeer, Mohammed Toufiq, Zohreh Tatari-Calderone, Sara Deola, Tobias Brummaier, Mathieu Garand, Ricardo Branco, Nicole Baldwin, Mohamed Alfaki, Matthew C. Altman, Alberto Ballestrero, Matteo Bassetti, Gabriele Zoppoli, Andrea De Maria, Benjamin Tang, Davide Bedognetti, Damien Chaussabel
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-23 (2020)
Abstract Background Covid-19 morbidity and mortality are associated with a dysregulated immune response. Tools are needed to enhance existing immune profiling capabilities in affected patients. Here we aimed to develop an approach to support the desi
Externí odkaz:
https://doaj.org/article/bb6ef7231df441fe8e35b6bd0d8cbb13
Autor:
Velma Herwanto, Benjamin Tang, Ya Wang, Maryam Shojaei, Marek Nalos, Amith Shetty, Kevin Lai, Anthony S. McLean, Klaus Schughart
Publikováno v:
BMC Research Notes, Vol 14, Iss 1, Pp 1-3 (2021)
Abstract Objectives Hospitalized patients who presented within the last 24 h with a bacterial infection were recruited. Participants were assigned into sepsis and uncomplicated infection groups. In addition, healthy volunteers were recruited as contr
Externí odkaz:
https://doaj.org/article/ab4e02d987534c1d8a0878aecb77a789
Autor:
Gha-Hyun J Kim, Han Mo, Harrison Liu, Zhihao Wu, Steven Chen, Jiashun Zheng, Xiang Zhao, Daryl Nucum, James Shortland, Longping Peng, Mannuel Elepano, Benjamin Tang, Steven Olson, Nick Paras, Hao Li, Adam R Renslo, Michelle R Arkin, Bo Huang, Bingwei Lu, Marina Sirota, Su Guo
Publikováno v:
eLife, Vol 10 (2021)
Parkinson’s disease (PD) is a common neurodegenerative disorder without effective disease-modifying therapeutics. Here, we establish a chemogenetic dopamine (DA) neuron ablation model in larval zebrafish with mitochondrial dysfunction and robustnes
Externí odkaz:
https://doaj.org/article/1a2b18fbbd014e52b754a5691eee90b7
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-12 (2019)
Abstract Background The effect of premorbid β-blocker exposure on clinical outcomes in patients with sepsis is not well characterized. We aimed to examine the association between premorbid β-blocker exposure and mortality in sepsis. Methods EMBase,
Externí odkaz:
https://doaj.org/article/a8467005c51242089f2f565fddf94649