Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Benjamin, Ory"'
Autor:
Maryne Dupuy, François Lamoureux, Mathilde Mullard, Anaïs Postec, Laura Regnier, Marc Baud’huin, Steven Georges, Bénédicte Brounais-Le Royer, Benjamin Ory, Françoise Rédini, Franck Verrecchia
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
In Europe, with an incidence of 7.5 cases per million, Ewing sarcoma (ES) is the second most common primary malignant bone tumor in children, adolescents and young adults, after osteosarcoma. Since the 1980s, conventional treatment has been based on
Externí odkaz:
https://doaj.org/article/96f03fca6f38466183cb1831951cf9a6
Autor:
Joséphine Briand, Aurélien A. Sérandour, Arulraj Nadaradjane, Gwenola Bougras-Cartron, Dominique Heymann, Benjamin Ory, François M. Vallette, Pierre-François Cartron
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 22, Iss , Pp 72-83 (2020)
MicroRNAs (miRNAs or miRs) play crucial roles in biological and pathological processes. Some miRNAs also appear as promising biomarkers and therapeutic tools. However, the epitranscriptomic regulation of miRNAs is not yet fully elucidated in all of t
Externí odkaz:
https://doaj.org/article/1923c4a8e922482c889c4a8688391f88
Autor:
Thomas GP Grünewald, Marta Alonso, Sofia Avnet, Ana Banito, Stefan Burdach, Florencia Cidre‐Aranaz, Gemma Di Pompo, Martin Distel, Heathcliff Dorado‐Garcia, Javier Garcia‐Castro, Laura González‐González, Agamemnon E Grigoriadis, Merve Kasan, Christian Koelsche, Manuela Krumbholz, Fernando Lecanda, Silvia Lemma, Dario L Longo, Claudia Madrigal‐Esquivel, Álvaro Morales‐Molina, Julian Musa, Shunya Ohmura, Benjamin Ory, Miguel Pereira‐Silva, Francesca Perut, Rene Rodriguez, Carolin Seeling, Nada Al Shaaili, Shabnam Shaabani, Kristina Shiavone, Snehadri Sinha, Eleni M Tomazou, Marcel Trautmann, Maria Vela, Yvonne MH Versleijen‐Jonkers, Julia Visgauss, Marta Zalacain, Sebastian J Schober, Andrej Lissat, William R English, Nicola Baldini, Dominique Heymann
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 11, Pp 1-33 (2020)
Abstract Sarcomas are heterogeneous and clinically challenging soft tissue and bone cancers. Although constituting only 1% of all human malignancies, sarcomas represent the second most common type of solid tumors in children and adolescents and compr
Externí odkaz:
https://doaj.org/article/32421af97ff64f339c73c8bfd6f57409
Autor:
Mathilde Cheray, Amandine Etcheverry, Camille Jacques, Romain Pacaud, Gwenola Bougras-Cartron, Marc Aubry, Florent Denoual, Pierre Peterlongo, Arulraj Nadaradjane, Joséphine Briand, Farida Akcha, Dominique Heymann, François M. Vallette, Jean Mosser, Benjamin Ory, Pierre-François Cartron
Publikováno v:
Molecular Cancer, Vol 19, Iss 1, Pp 1-16 (2020)
Abstract Background Literature reports that mature microRNA (miRNA) can be methylated at adenosine, guanosine and cytosine. However, the molecular mechanisms involved in cytosine methylation of miRNAs have not yet been fully elucidated. Here we inves
Externí odkaz:
https://doaj.org/article/559fa47d8d234bfea3bb4d6081c35783
Autor:
Sarah Morice, Geoffroy Danieau, Robel Tesfaye, Mathilde Mullard, Régis Brion, Maryne Dupuy, Benjamin Ory, Bénédicte Brounais-Le Royer, Isabelle Corre, Françoise Redini, Franck Verrecchia
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundThe poor survival rate of patients with osteosarcoma (OS), specifically with metastases at diagnosis, undergoes the urgency to develop new therapeutic strategies. Although we recently demonstrated the key role of YAP/TEAD signaling in the g
Externí odkaz:
https://doaj.org/article/457682109eb140a78fb4f0625062e444
Autor:
Brice Moukengue, Hannah K Brown, Céline Charrier, Séverine Battaglia, Marc Baud'huin, Thibaut Quillard, Therese M Pham, Ioannis S Pateras, Vassilis G Gorgoulis, Thomas Helleday, Dominique Heymann, Ulrika Warpman Berglund, Benjamin Ory, Francois Lamoureux
Publikováno v:
EBioMedicine, Vol 53, Iss , Pp - (2020)
ABSTRACT: Background: Osteosarcoma (OS) is the most common primary malignant bone tumour. Unfortunately, no new treatments are approved and over the last 30 years the survival rate remains only 30% at 5 years for poor responders justifying an urgent
Externí odkaz:
https://doaj.org/article/4adcf80b973340c5acc405a66af0dad8
Autor:
Camille Jacques, Nathalie Renema, Frederic Lezot, Benjamin Ory, Carl R. Walkley, Agamemnon E. Grigoriadis, Dominique Heymann
Publikováno v:
Journal of Bone Oncology, Vol 12, Iss , Pp 7-13 (2018)
Osteosarcoma, Ewing sarcoma and chondrosarcoma are the three main entities of bone sarcoma which collectively encompass more than 50 heterogeneous entities of rare malignancies. In contrast to osteosarcoma and Ewing sarcoma which mainly affect adoles
Externí odkaz:
https://doaj.org/article/03b38a9800d24415a83a470902a27fe5
Autor:
Mélanie Lavaud, Mathilde Mullard, Robel Tesfaye, Jérôme Amiaud, Mélanie Legrand, Geoffroy Danieau, Régis Brion, Sarah Morice, Laura Regnier, Maryne Dupuy, Bénédicte Brounais-Le Royer, François Lamoureux, Benjamin Ory, Françoise Rédini, Franck Verrecchia
Publikováno v:
Cells, Vol 10, Iss 9, p 2268 (2021)
Osteosarcoma (OS) is the most common malignant bone tumor in children and teenagers. In many cases, such as poor response to treatment or the presence of metastases at diagnosis, the survival rate of patients remains very low. Although in the literat
Externí odkaz:
https://doaj.org/article/f4f1de5beefe4f708ca38780054a85d1
Autor:
Morgane Lallier, Louise Marchandet, Brice Moukengue, Celine Charrier, Marc Baud’huin, Franck Verrecchia, Benjamin Ory, François Lamoureux
Publikováno v:
Cells, Vol 10, Iss 4, p 754 (2021)
Osteosarcoma (OS) is the most common form of primary bone tumor affecting mainly children and young adults. Despite therapeutic progress, the 5-year survival rate is 70%, but it drops drastically to 30% for poor responders to therapies or for patient
Externí odkaz:
https://doaj.org/article/386f818b921844b3b72e8a6188a63100
Autor:
Maryne Dupuy, Maxime Gueguinou, Anaïs Postec, Régis Brion, Robel Tesfaye, Mathilde Mullard, Laura Regnier, Jérôme Amiaud, Marie Potier-Cartereau, Aurélie Chantôme, Bénédicte Brounais-Le Royer, Marc Baud’huin, Steven Georges, François Lamoureux, Benjamin Ory, Olivier Delattre, Françoise Rédini, Christophe Vandier, Franck Verrecchia
Ewing sarcoma (ES) is characterized by chimeric fusion proteins, which act as oncogenes. Over the last decade, patient survival has not increased, especially for high risk patients. Knowing that ion channels are studied for their implication in tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf5f6ff0ab756b2938f46bf90990c438
https://doi.org/10.1101/2023.04.24.538050
https://doi.org/10.1101/2023.04.24.538050