Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Benjamin, Muirhead"'
Autor:
Mitchell Ross, Lindsay Sheardown, Benjamin Muirhead, Jonathan Mofford, Jennifer (JingYuan) Tian, Heather Sheardown
Publikováno v:
Journal of Biomedical Materials Research Part A.
Autor:
Mitchell, Ross, Jonathan, Mofford, Jennifer JingYuan, Tian, Benjamin, Muirhead, Emily Anne, Hicks, Lindsay, Sheardown, Heather, Sheardown
Publikováno v:
Biomaterials Advances. 144:213235
Mucoadhesive thermogels were developed by crosslinking poly(n-isopropylacrylamide) based polymers with chitosan and incorporating disulfide bridges, capable of releasing cysteamine upon interaction with mucin, for the treatment of cystinosis. Through
Publikováno v:
Biomacromolecules. 17(4)
Topical drug delivery to the front of the eye is extremely inefficient due to effective natural protection mechanisms such as precorneal tear turnover and the relative impermeability of the cornea and sclera tissues. This causes low ocular drug bioav
Publikováno v:
Journal of biomedical materials research. Part B, Applied biomaterials. 105(1)
The sustained release of ophthalmic therapeutics to the posterior segment of the eye is a challenge. Injectable polymer materials have the potential to reduce injection frequency by providing long term therapeutic delivery. Copolymers with varying N-
Publikováno v:
Acta biomaterialia. 8(7)
Copolymers based on N-isopropylacrylamide (NIPAAm), acrylic acid N-hydroxysuccinimide (NAS) and varying concentrations of acrylic acid (AA) and acryloyloxy dimethyl-γ-butyrolactone (DBA) were synthesized to create thermoresponsive, resorbable copoly