Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Benjamin, Kirchweger"'
Autor:
Andreas Wasilewicz, Julia Zwirchmayr, Benjamin Kirchweger, Denisa Bojkova, Jindrich Cinatl, Holger F. Rabenau, Judith M. Rollinger, Mehdi A. Beniddir, Ulrike Grienke
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
A pigment-depleted extract from the heartwood of Pterocarpus santalinus L. f. (PS-DE) showed promising anti-SARS-CoV-2 activity with an IC50 of 29.9 μg/mL in Caco-2-F03 cells. To determine the potential active constituents within the extract prior t
Externí odkaz:
https://doaj.org/article/c376f21a6ee348b8ae8cc1ebfd1058f4
Autor:
Athanasios S. Arampatzis, Olga Tsave, Benjamin Kirchweger, Julia Zwirchmayr, Vassilios P. Papageorgiou, Judith M. Rollinger, Andreana N. Assimopoulou
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Alkannin, shikonin (A/S) and their derivatives are naturally occurring hydroxynaphthoquinones biosynthesized in some species of the Boraginaceae family. These natural compounds have been extensively investigated for their biological properties over t
Externí odkaz:
https://doaj.org/article/203f385a994449df8b6ea5a68310f563
Autor:
Benjamin Kirchweger, Luiz C. Klein-Junior, Dagmar Pretsch, Ya Chen, Sylvian Cretton, André L. Gasper, Yvan Vander Heyden, Philippe Christen, Johannes Kirchmair, Amélia T. Henriques, Judith M. Rollinger
Publikováno v:
Frontiers in Neuroscience, Vol 16 (2022)
Nemorosine A (1) and fargesine (2), the main azepine-indole alkaloids of Psychotria nemorosa, were explored for their pharmacological profile on neurodegenerative disorders (NDs) applying a combined in silico–in vitro–in vivo approach. By using 1
Externí odkaz:
https://doaj.org/article/6a8f1704be004251a23ef4db743ccbe3
Autor:
Julia Zwirchmayr, Benjamin Kirchweger, Theresa Lehner, Ammar Tahir, Dagmar Pretsch, Judith M. Rollinger
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Abstract In this study a robust, whole organism screening based on Caenorhabditis elegans is presented for the discovery of natural products (NP) with beneficial effects against obesity and age-related diseases. Several parameters of the elaborated w
Externí odkaz:
https://doaj.org/article/07fdb2401ccd4e7abf75d0a961d73f3b
Publikováno v:
Applied Sciences, Vol 11, Iss 23, p 11420 (2021)
The small and transparent nematode Caenorhabditis elegans is increasingly employed for phenotypic in vivo chemical screens. The influence of compounds on worm body fat stores can be assayed with Nile red staining and imaging. Segmentation of C. elega
Externí odkaz:
https://doaj.org/article/81fc309e6aa24859a15b54820a03e906
Autor:
Andreas Wasilewicz, Benjamin Kirchweger, Denisa Bojkova, Marie Jose Abi Saad, Julia Langeder, Matthias Bütikofer, Sigrid Adelsberger, Ulrike Grienke, Jindrich Cinatl Jr., Olivier Petermann, Leonardo Scapozza, Julien Orts, Johannes Kirchmair, Holger F. Rabenau, Judith M. Rollinger
Publikováno v:
Journal of Natural Products, 86 (2)
In this study, an integrated in silico-in vitro approach was employed to discover natural products (NPs) active against SARS-CoV-2. The two SARS-CoV-2 viral proteases, i.e., main protease (Mpro) and papain-like protease (PLpro), were selected as targ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a90f9060f46bb8491cdcda6433aa244a
Autor:
Benjamin Kirchweger, Jadel M. Kratz, Angela Ladurner, Ulrike Grienke, Thierry Langer, Verena M. Dirsch, Judith M. Rollinger
Publikováno v:
Frontiers in Chemistry, Vol 6 (2018)
The G protein-coupled bile acid receptor (GPBAR1) has been recognized as a promising new target for the treatment of diverse diseases, including obesity, type 2 diabetes, fatty liver disease and atherosclerosis. The identification of novel and potent
Externí odkaz:
https://doaj.org/article/c0afcca1828e4f18980f618a8eb4299a
Autor:
Judith M. Rollinger, Theresa Lehner, Ammar Tahir, Benjamin Kirchweger, Dagmar Pretsch, Julia Zwirchmayr
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
In this study a robust, whole organism screening based on Caenorhabditis elegans is presented for the discovery of natural products (NP) with beneficial effects against obesity and age-related diseases. Several parameters of the elaborated workflow w
Autor:
Benjamin, Kirchweger, Luiz C, Klein-Junior, Dagmar, Pretsch, Ya, Chen, Sylvian, Cretton, André L, Gasper, Yvan Vander, Heyden, Philippe, Christen, Johannes, Kirchmair, Amélia T, Henriques, Judith M, Rollinger
Publikováno v:
Frontiers in neuroscience. 16
Nemorosine A (
Autor:
T Lehner, Ammar Tahir, Judith M. Rollinger, Julia Zwirchmayr, Benjamin Kirchweger, Dagmar Pretsch
Publikováno v:
67th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA) in cooperation with the French Society of Pharmacognosy AFERP.