Zobrazeno 1 - 10
of 159
pro vyhledávání: '"Benjamin, Dekel"'
Autor:
Naomi Pode-Shakked, Megan Slack, Nambirajan Sundaram, Ruth Schreiber, Kyle W. McCracken, Benjamin Dekel, Michael Helmrath, Raphael Kopan
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Autosomal Recessive Renal Tubular Dysgenesis (AR-RTD) is a fatal genetic disorder characterized by complete absence or severe depletion of proximal tubules (PT) in patients harboring pathogenic variants in genes involved in the Renin–Angio
Externí odkaz:
https://doaj.org/article/21f90e81a5fe4cb28b323e95f795a5d6
Autor:
Dorit Omer, Osnat Cohen Zontag, Yehudit Gnatek, Orit Harari-Steinberg, Oren Pleniceanu, Michael Namestnikov, Ayelet-Hashahar Cohen, Malka Nissim-Rafinia, Gal Tam, Tomer Kalisky, Eran Meshorer, Benjamin Dekel
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 29, Iss , Pp 329-346 (2023)
Upscaling of kidney epithelial cells is crucial for renal regenerative medicine. Nonetheless, the adult kidney lacks a distinct stem cell hierarchy, limiting the ability to long-term propagate clonal populations of primary cells that retain renal ide
Externí odkaz:
https://doaj.org/article/2816b5ae0eef4665ac0e00b61574ad07
Autor:
Yishay Wineberg, Itamar Kanter, Nissim Ben-Haim, Naomi Pode-Shakked, Efrat Bucris, Tali Hana Bar-Lev, Sarit Oriel, Harel Reinus, Yishai Yehuda, Rotem Gershon, Rachel Shukrun, Dekel Dov Bar-Lev, Achia Urbach, Benjamin Dekel, Tomer Kalisky
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-13 (2022)
Abstract Nephrons are the functional units of the kidney. During kidney development, cells from the cap mesenchyme—a transient kidney-specific progenitor state—undergo a mesenchymal to epithelial transition (MET) and subsequently differentiate in
Externí odkaz:
https://doaj.org/article/e0c40f40f54d4a0192db098dd6e00014
Autor:
Marjan Huizing, Tal Yardeni, Federico Fuentes, May C.V. Malicdan, Petcharat Leoyklang, Alexander Volkov, Benjamin Dekel, Emily Brede, Jodi Blake, Alva Powell, Harish Chatrathi, Yair Anikster, Nuria Carrillo, William A. Gahl, Jeffrey B. Kopp
Publikováno v:
Kidney International Reports, Vol 4, Iss 10, Pp 1454-1462 (2019)
Introduction: Sialic acids are important contributors to the polyanionic component of the glomerular filtration barrier, which regulates permeability selectivity. Pathologic glomerular hyposialylation, associated with podocyte effacement, has been im
Externí odkaz:
https://doaj.org/article/95a3cca4c1844c918ae56167d6ccdca6
Autor:
Benjamin S. Freedman, Benjamin Dekel
Publikováno v:
Current Transplantation Reports. 10:29-39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d075ca14cd935b05edb18642f17edaf
https://doi.org/10.1007/s40472-023-00397-2
https://doi.org/10.1007/s40472-023-00397-2
Autor:
Orit Harari-Steinberg, Dorit Omer, Yehudit Gnatek, Oren Pleniceanu, Sanja Goldberg, Osnat Cohen-Zontag, Sara Pri-Chen, Itamar Kanter, Nissim Ben Haim, Eli Becker, Roi Ankawa, Yaron Fuchs, Tomer Kalisky, Zohar Dotan, Benjamin Dekel
Publikováno v:
Cell Reports, Vol 30, Iss 3, Pp 852-869.e4 (2020)
Summary: End-stage renal disease is a worldwide epidemic requiring renal replacement therapy. Harvesting tissue from failing kidneys and autotransplantation of tissue progenitors could theoretically delay the need for dialysis. Here we use healthy an
Externí odkaz:
https://doaj.org/article/9d98aec17bda4af89b45646d801e3a42
Autor:
Hana Golan, Rachel Shukrun, Revital Caspi, Einav Vax, Naomi Pode-Shakked, Sanja Goldberg, Oren Pleniceanu, Dekel D. Bar-Lev, Michal Mark-Danieli, Sara Pri-Chen, Jasmine Jacob-Hirsch, Itamar Kanter, Ariel Trink, Ginette Schiby, Ron Bilik, Tomer Kalisky, Orit Harari-Steinberg, Amos Toren, Benjamin Dekel
Publikováno v:
Stem Cell Reports, Vol 11, Iss 3, Pp 795-810 (2018)
Summary: Cancer stem cell (CSC) identification relies on transplantation assays of cell subpopulations sorted from fresh tumor samples. Here, we attempt to bypass limitations of abundant tumor source and predetermined immune selection by in vivo prop
Externí odkaz:
https://doaj.org/article/c8975f3987c644cb807934810287d3c9
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 20, Iss 8, Pp 871-881 (2018)
Wilms' tumor is a pediatric malignancy that is thought to originate from faulty kidney development during the embryonic stage. However, there is a large variation between tumors from different patients in both histology and gene expression that is no
Externí odkaz:
https://doaj.org/article/a3026384a0d84ac69cfdb2c45e8ec968
Publikováno v:
Kidney International Reports, Vol 3, Iss 1, Pp 155-159 (2018)
Renal angiomyolipoma (AML) is the most common benign renal tumor. Despite a generally benign histology, AML can result in significant morbidity, from intra-abdominal hemorrhage and reduction in kidney function. While classically associated with the a
Externí odkaz:
https://doaj.org/article/b72d2bbf51cb4b6ba37c2077b1db75d7
Autor:
Naomi Pode-Shakked, Rotem Gershon, Gal Tam, Dorit Omer, Yehudit Gnatek, Itamar Kanter, Sarit Oriel, Guy Katz, Orit Harari-Steinberg, Tomer Kalisky, Benjamin Dekel
Publikováno v:
Stem Cell Reports, Vol 9, Iss 1, Pp 279-291 (2017)
During nephrogenesis, stem/progenitor cells differentiate and give rise to early nephron structures that segment to proximal and distal nephron cell types. Previously, we prospectively isolated progenitors from human fetal kidney (hFK) utilizing a co
Externí odkaz:
https://doaj.org/article/d8cb8a41442a4e62802a6d3cc08bb555