Výsledky vyhledávání - "Beni Lestari"

Akademický článek

Preparation and Cytotoxic Evaluation of PGV-1 Derivative, CCA-1.1, as a New Curcumin Analog with Improved-Physicochemical and Pharmacological Properties

Autor: Rohmad Yudi Utomo, Febri Wulandari, Dhania Novitasari, Beni Lestari, Ratna Asmah Susidarti, Riris Istighfari Jenie, Jun-ya Kato, Sardjiman Sardjiman, Edy Meiyanto

Publikováno v: Advanced Pharmaceutical Bulletin, Vol 12, Iss 3, Pp 603-612 (2022)

Purpose: This study aimed to challenge the anticancer potency of pentagamavunone-1 (PGV-1) and obtain a new compound (Chemoprevention-Curcumin Analog 1.1, CCA-1.1) withimproved chemical and pharmacological properties.Methods: CCA-1.1 was prepared by

Externí odkaz: https://doaj.org/article/bf29d6a4b10c454caa5205af1050d78e

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Akademický článek

CEP55 Inhibitor: Extensive Computational Approach Defining a New Target of Cell Cycle Machinery Agent

Autor: Beni Lestari, Rohmad Yudi Utomo

Publikováno v: Advanced Pharmaceutical Bulletin, Vol 12, Iss 1, Pp 191-199 (2022)

Purpose: Centrosomal protein 55 (CEP55) is a pivotal protein for cytokinesis during cell division. This study aimed to provide a comprehensive information about the CEP55 gene, including its expression pattern in several cancer types, conduct functio

Externí odkaz: https://doaj.org/article/e795d9a7643b41bdbf1a3eaf3c9ec9aa

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Akademický článek

The Target Differences of Anti-Tumorigenesis Potential of Curcumin and its Analogues Against HER-2 Positive and Triple-Negative Breast Cancer Cells

Autor: Edy Meiyanto, Ulfatul Husnaa, Ria Fajarwati Kastian, Herwandhani Putri, Yonika Arum Larasati, Annisa Khumaira, Dyaningtyas Dewi Putri Pamungkas, Riris Istighfari Jenie, Masashi Kawaichi, Beni Lestari, Takashi Yokoyama, Jun-ya Kato

Publikováno v: Advanced Pharmaceutical Bulletin, Vol 11, Iss 1, Pp 188-196 (2021)

Purpose: The current study aims to evaluate the in vitro cytotoxic and cell migration effects of synthetic curcumin and its analogues on HER2 and nuclear factor kappa B (NFκB) pathways, as well as the in vivo inhibitory effect on cancer growth of me

Externí odkaz: https://doaj.org/article/a5c473521a65455ba9a443a4d99aea6f

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Akademický článek

Anti-proliferative and Anti-metastatic Potential of Curcumin Analogue, Pentagamavunon-1 (PGV-1), Toward Highly Metastatic Breast Cancer Cells in Correlation with ROS Generation

Autor: Edy Meiyanto, Herwandhani Putri, Yonika Arum Larasati, Rohmad Yudi Utomo, Riris Istighfari Jenie, Muthi Ikawati, Beni Lestari, Noriko Yoneda-Kato, Ikuko Nakamae, Masashi Kawaichi, Jun-Ya Kato

Publikováno v: Advanced Pharmaceutical Bulletin, Vol 9, Iss 3, Pp 445-452 (2019)

Purpose: Pentagamavunon-1 (PGV-1) is a curcumin analogue that shows cytotoxic activity in various cancer cells. In this study, we evaluated the effect of PGV-1 on a highly metastatic breast cancer cell line, the 4T1 cells, as an anti-metastatic and a

Externí odkaz: https://doaj.org/article/b2b1d53cbef44081ae050af06c0e71fb

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Akademický článek

A Review: The Emerging Nutraceutical Potential of Pumpkin Seeds

Autor: Beni Lestari, Edy Meiyanto

Publikováno v: ISCC (Indonesian Journal of Cancer Chemoprevention), Vol 9, Iss 2, Pp 92-101 (2018)

The pumpkin belongs to the family of Cucurbitaceae, is a well-known edible plant that has been frequently used as functional food or herbal medicine. Pumpkins contain rich unsaturated fatty acids, phytoestrogens and vitamins E in their seeds that hav

Externí odkaz: https://doaj.org/article/a3a8cc42b4664047a309f19f83d064c7

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Akademický článek

Reveal Cytotoxicity and Antigenotoxicity of Piper nigrum L. Ethanolic Extract and its Combination with Doxorubicin on CHO-K1 Cells

Autor: Nur Fitra Sari, Beni Lestari, Dian Saputri, Anisa Fauzia Ahsani, Ragil Anang Santoso, Ediati Sasmito, Edy Meiyanto

Publikováno v: ISCC (Indonesian Journal of Cancer Chemoprevention), Vol 8, Iss 3, Pp 110-119 (2018)

Black pepper (Piper nigrum L.), one of the most popular Indonesian spices has been reported to possess various therapeutic effects. The aim of this study is to evaluate the cytotoxicity and antigenotoxicity of black pepper ethanolic extract (BPE) and

Externí odkaz: https://doaj.org/article/661274c1609b45af8e4fb787958e75ab

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Akademický článek

Evaluation of The Genotoxicity of Three Food Additives using CHO-K1 Cells under in vitro Micronucleus Flow Cytometry Assay

Autor: Beni Lestari, Dhania Novitasari, Herwandhani Putri, Sari Haryanti, Ediati Sasmito, Edy Meiyanto

Publikováno v: ISCC (Indonesian Journal of Cancer Chemoprevention), Vol 8, Iss 2, Pp 74-80 (2017)

Exposure of genotoxic substances come from various sources such as food additives. The aim of this study is to evaluate the genotoxicity of food additives in CHO-K1 cells by micronucleus test flow cytometry. The food additives: sodium saccharine (SS)

Externí odkaz: https://doaj.org/article/2ee26d1723444556ab5d7578db314bef

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Akademický článek

A Comparison of Antimetastatic Activity between Nerium indicum and Cinnamomum burmannii on 4T1 Cells

Autor: Beni Lestari, Laeli Muntafiah, Ziana Walidah, Riris Istighfari Jenie

Publikováno v: ISCC (Indonesian Journal of Cancer Chemoprevention), Vol 8, Iss 2, Pp 85-93 (2017)

Metastatic process becomes a major problem in advanced cancer cases. Natural compounds found in several plants in Indonesia have a potency to be developed as chemoterapeutic agent which are targeted to metastatic process. Jure leaves (Nerium indicum)

Externí odkaz: https://doaj.org/article/c0b9a2075573494bb2b941955c392377

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