The use of multiplex platforms for absolute and relative protein quantification of clinical material

Autor: Lisa Christiansson, Satu Mustjoki, Bengt Simonsson, Ulla Olsson-Strömberg, Angelica S.I. Loskog, Sara M. Mangsbo

Publikováno v: EuPA Open Proteomics, Vol 3, Iss C, Pp 37-47 (2014)

When introducing multiplex platforms to measure protein content in precious clinical material there is an increased risk of cross reactivity, loss of sensitivity as well as accuracy. In this paper, four multiplex platforms and one singleplex platform

Externí odkaz: https://doaj.org/article/c6349e31a24c453f9d90cf061cf9ffb4

The European LeukemiaNet: achievements and perspectives

Autor: Rüdiger Hehlmann, David Grimwade, Bengt Simonsson, Jane Apperley, Michele Baccarani, Tiziano Barbui, Giovanni Barosi, Renato Bassan, Marie C. Béné, Ute Berger, Thomas Büchner, Alan Burnett, Nicolas C.P. Cross, Theo J.M. de Witte, Hartmut Döhner, Hervé Dombret, Hermann Einsele, Georg Engelich, Robin Foà, Christa Fonatsch, Nicola Gökbuget, Elaine Gluckman, Alois Gratwohl, Francois Guilhot, Claudia Haferlach, Thorsten Haferlach, Michael Hallek, Jörg Hasford, Andreas Hochhaus, Dieter Hoelzer, Jean-Jaques Kiladjian, Boris Labar, Per Ljungman, Ulrich Mansmann, Dietger Niederwieser, Gert Ossenkoppele, José M. Ribera, Harald Rieder, Hubert Serve, Petra Schrotz-King, Miguel A. Sanz, Susanne Saußele

Publikováno v: Haematologica, Vol 96, Iss 1 (2011)

The only way to cure leukemia is by cooperative research. To optimize research, the European LeukemiaNet integrates 105 national leukemia trial groups and networks, 105 interdisciplinary partner groups and about 1,000 leukemia specialists from 175 in

Externí odkaz: https://doaj.org/article/8876d1f1a9dc493dacbb68ef3f24a52e

Tyrosine kinase inhibitor interruptions, discontinuations and switching in patients with chronic-phase chronic myeloid leukemia in routine clinical practice: SIMPLICITY

Autor: Srikanth Gajavelli, Loretta A. Williams, Mauricette Michallet, Ron Paquette, Irene DeGutis, Ruediger Hehlmann, Jorge E. Cortes, Teresa Zyczynski, Michael J. Mauro, Ginny P Sen, Carlo Gambacorti-Passerini, Bengt Simonsson, Stuart L. Goldberg

Publikováno v: American Journal of Hematology

SIMPLICITY (NCT01244750) is an observational study exploring tyrosine kinase inhibitor (TKI) use and management patterns in patients with chronic phase‐chronic myeloid leukemia in the US and Europe in routine clinical practice. Herein we describe i

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf757800bc84051386bb54526e10caf5
https://doi.org/10.1002/ajh.25306

First-line treatment selection and early monitoring patterns in chronic phase-chronic myeloid leukemia in routine clinical practice : SIMPLICITY

Autor: Pascale Cony-Makhoul, Carlo Gambacorti-Passerini, Elza Lomaia, Ruediger Hehlmann, Bengt Simonsson, Michael J. Mauro, Aart Beeker, Mauricette Michallet, Eduardo Olavarria, Stuart L. Goldberg, Richard M. Hansen, Elisabetta Abruzzese, David Andorsky, Aimee Foreman, Jorge E. Cortes, Teresa Zyczynski, H. Jean Khoury, Ron Paquette

Publikováno v: American Journal of Hematology

Achieving successful outcomes in chronic phase‐chronic myeloid leukemia (CP‐CML) requires careful monitoring of cytogenetic/molecular responses (CyR/MR). SIMPLICITY (NCT01244750) is an observational study exploring tyrosine kinase inhibitor use a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22ad2e6a3c4d932c21654f5abea0ec46
http://urn.kb.se/resolve?urn=urn:nbn:se:uu:diva-339738

Treatment and outcome of 2 904 CML patients from the EUTOS population based registry

Autor: Gert J. Ossenkoppele, Dubravka Sertić, Perttu Koskenvesa, L.F. Casado, Doris Lindoerfer, F. Di Raimondo, Andrzej Hellmann, Andrija Bogdanovic, Verena S. Hoffmann, Irena Preloznik Zupan, Daniela Zackova, Laimonas Griskevicius, Fausto Castagnetti, Karel Indrak, Sonja Burgstaller, Martin Höglund, Michele Baccarani, Andrey Zaritskey, Ruediger Hehlmann, Joelle Guilhot, Paul Costeas, Anna G. Turkina, Sandra Lejniece, Tomasz Sacha, Richard E. Clark, Joerg Hasford, Andreas Hochhaus, Susanne Saussele, Zuzana Sninská, Gabriele Schubert-Fritschle, Hele Everaus, Gianantonio Rosti, Bengt Simonsson

Publikováno v: Leukemia, 31(3), 593-601. Nature Publishing Group
Hoffmann, V S, Baccarani, M, Hasford, J, Castagnetti, F, Di Raimondo, F, Casado, L F, Turkina, A, Zackova, D, Ossenkoppele, G, Zaritskey, A, Höglund, M, Simonsson, B, Indrak, K, Sninska, Z, Sacha, T, Clark, R, Bogdanovic, A, Hellmann, A, Griskevicius, L, Schubert-Fritschle, G, Sertic, D, Guilhot, J, Lejniece, S, Zupan, I, Burgstaller, S, Koskenvesa, P, Everaus, H, Costeas, P, Lindoerfer, D, Rosti, G, Saussele, S, Hochhaus, A & Hehlmann, R 2017, ' Treatment and outcome of 2904 CML patients from the EUTOS population-based registry ', Leukemia, vol. 31, no. 3, pp. 593-601 . https://doi.org/10.1038/leu.2016.246

The European Treatment and Outcome Study (EUTOS) population-based registry includes data of all adult patients newly diagnosed with Philadelphia chromosome-positive and/or BCR-ABL1+ chronic myeloid leukemia (CML) in 20 predefined countries and region

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::187685d518aa1801d232adea9a7163ab
http://hdl.handle.net/20.500.11769/45823